$510 Cheap Flights from Hermosillo (HMO) to Panama City (PTY)

View $510 flight on Tue, Mar 3, 2026Opens in a new window

Popular airlines from Hermosillo, Sonora (HMO-General Ignacio Pesqueira Garcia Intl.) to Tocumen Intl. Airport (PTY)

Cheap Flights from Hermosillo to Panama City (HMO-PTY)

Prices were available within the past 7 days and start at $510 for one-way flights and $687 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Wed, Dec 31 - Wed, Jan 14
HMO
Hermosillo
PTY
Panama City
$687 Roundtrip, found 5 days ago
$687
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Wed, Dec 31 from Hermosillo to Panama City, returning Wed, Jan 14, priced at $687 found 5 days ago
Aeromexico
Mon, Dec 15 - Tue, Dec 30
HMO
Hermosillo
PTY
Panama City
$693 Roundtrip, found 5 days ago
$693
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Mon, Dec 15 from Hermosillo to Panama City, returning Tue, Dec 30, priced at $693 found 5 days ago
Aeromexico
Tue, Dec 30 - Wed, Jan 14
HMO
Hermosillo
PTY
Panama City
$696 Roundtrip, found 5 days ago
$696
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Tue, Dec 30 from Hermosillo to Panama City, returning Wed, Jan 14, priced at $696 found 5 days ago
Aeromexico
Tue, Dec 16 - Tue, Dec 30
HMO
Hermosillo
PTY
Panama City
$714 Roundtrip, found 5 days ago
$714
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Tue, Dec 16 from Hermosillo to Panama City, returning Tue, Dec 30, priced at $714 found 5 days ago
Aeromexico
Sun, Dec 21 - Wed, Jan 7
HMO
Hermosillo
PTY
Panama City
$727 Roundtrip, found 5 days ago
$727
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Sun, Dec 21 from Hermosillo to Panama City, returning Wed, Jan 7, priced at $727 found 5 days ago
Aeromexico
Mon, Nov 24 - Wed, Dec 10
HMO
Hermosillo
PTY
Panama City
$743 Roundtrip, found 5 days ago
$743
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Mon, Nov 24 from Hermosillo to Panama City, returning Wed, Dec 10, priced at $743 found 5 days ago
Aeromexico
Sat, Nov 29 - Thu, Dec 18
HMO
Hermosillo
PTY
Panama City
$748 Roundtrip, found 5 days ago
$748
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Sat, Nov 29 from Hermosillo to Panama City, returning Thu, Dec 18, priced at $748 found 5 days ago
Aeromexico
Mon, Dec 1 - Thu, Dec 18
HMO
Hermosillo
PTY
Panama City
$753 Roundtrip, found 5 days ago
$753
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Mon, Dec 1 from Hermosillo to Panama City, returning Thu, Dec 18, priced at $753 found 5 days ago
Aeromexico
Sat, Dec 6 - Mon, Dec 22
HMO
Hermosillo
PTY
Panama City
$764 Roundtrip, found 5 days ago
$764
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Sat, Dec 6 from Hermosillo to Panama City, returning Mon, Dec 22, priced at $764 found 5 days ago
American Airlines
Tue, Mar 3 - Mon, Mar 9
HMO
Hermosillo
PTY
Panama City
$1,107 Roundtrip, found 3 days ago
$1,107
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Mar 3 from Hermosillo to Panama City, returning Mon, Mar 9, priced at $1,107 found 3 days ago

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $880
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $880
Flights from Hermosillo (HMO) to Panama City (PTY)
Origin airport
General Ignacio Pesqueira Garcia Intl.
Destination airport
Tocumen Intl.
Airlines serving
Aeromexico
Roundtrip price
$686
Distance
2473 mi

Hermosillo to Panama City Flights

The cheapest times to fly from Hermosillo to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Hermosillo to Panama City are during the month of December. You can find some of the cheapest flights from Hermosillo to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Hermosillo to Panama City

Sunday is one of the best days to book for cheap flights from Hermosillo to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Hermosillo to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Hermosillo to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $510 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Hermosillo to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Hermosillo to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from General Ignacio Pesqueira Garcia Intl. Airport (HMO) to Tocumen Intl. Airport (PTY) cost?
Lock in a cheap one-way flight from $510 or cheap return flight from $687 from General Ignacio Pesqueira Garcia Intl. Airport (HMO) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from General Ignacio Pesqueira Garcia Intl. Airport (HMO) to Tocumen Intl. Airport (PTY)?
December is the cheapest month to fly from HMO to PTY. Avoiding peak travel times is often the key to finding a great deal.
What is the cheapest airline that flies from General Ignacio Pesqueira Garcia Intl. Airport (HMO) to Tocumen Intl. Airport (PTY)?
Use the filters on Expedia to compare different airlines and find the most affordable carrier that'll take you from HMO to PTY. Then, sort your results by "Price (lowest to highest)" to score a great deal.
How many flights per day from General Ignacio Pesqueira Garcia Intl. Airport (HMO) to Tocumen Intl. Airport (PTY)?
There are no daily nonstop flights departing from General Ignacio Pesqueira Garcia Intl. Airport (HMO) to Tocumen Intl. Airport (PTY). But you can choose flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be on your way in no time at all.
What day of the week has the most flights from HMO to PTY?
You'll typically find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from General Ignacio Pesqueira Garcia Intl. Airport (HMO) to Tocumen Intl. Airport (PTY)?
Choose a flight from General Ignacio Pesqueira Garcia Intl. Airport (HMO) to Tocumen Intl. Airport (PTY) that takes off before 3 PM to reduce the risk of delays and cancellations. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from General Ignacio Pesqueira Garcia Intl. Airport (HMO) to Tocumen Intl. Airport (PTY) last-minute?
Waiting until just before your trip to book a flight from HMO to PTY generally means paying more. While it's possible to find some last-minute deals, they aren't always guaranteed. Be flexible with your travel plans to boost your chances of snagging a bargain.
Is it cheaper to book a HMO to PTY flight and hotel package?
Opting for a HMO to PTY flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Pick from our extensive range of hotels and then add car rentals, activities and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from General Ignacio Pesqueira Garcia Intl. Airport (HMO) to Tocumen Intl. Airport (PTY)?
If you reserved your HMO to PTY flight within the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more details.

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*Available to One Key members.