$232 Cheap Flights from Indianapolis (IND) to Panama City (PTY)

View $232 flight on Mon, Mar 16, 2026Opens in a new window

Popular airlines from Indianapolis Intl. Airport (IND) to Tocumen Intl. Airport (PTY)

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Cheap Flights from Indianapolis to Panama City (IND-PTY)

Prices were available within the past 7 days and start at $232 for one-way flights and $490 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Thu, Apr 23 - Tue, Apr 28
IND
Indianapolis
PTY
Panama City
$490 Roundtrip, found 2 days ago
$490
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Apr 23 from Indianapolis to Panama City, returning Tue, Apr 28, priced at $490 found 2 days ago
Delta
Thu, Mar 12 - Wed, Mar 18
IND
Indianapolis
PTY
Panama City
$490 Roundtrip, found 18 hours ago
$490
Roundtrip
found 18 hours ago
Select Delta flight, departing Thu, Mar 12 from Indianapolis to Panama City, returning Wed, Mar 18, priced at $490 found 18 hours ago
United
Mon, Mar 16 - Tue, Mar 24
IND
Indianapolis
PTY
Panama City
$490 Roundtrip, found 5 hours ago
$490
Roundtrip
found 5 hours ago
Select United flight, departing Mon, Mar 16 from Indianapolis to Panama City, returning Tue, Mar 24, priced at $490 found 5 hours ago
American Airlines
Thu, Mar 19 - Wed, Mar 25
IND
Indianapolis
PTY
Panama City
$494 Roundtrip, found 15 hours ago
$494
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Thu, Mar 19 from Indianapolis to Panama City, returning Wed, Mar 25, priced at $494 found 15 hours ago
Delta
Sun, Mar 22 - Wed, Mar 25
IND
Indianapolis
PTY
Panama City
$498 Roundtrip, found 15 hours ago
$498
Roundtrip
found 15 hours ago
Select Delta flight, departing Sun, Mar 22 from Indianapolis to Panama City, returning Wed, Mar 25, priced at $498 found 15 hours ago
United
Mon, Mar 16 - Tue, Mar 24
IND
Indianapolis
PTY
Panama City
$499 Roundtrip, found 5 hours ago
$499
Roundtrip
found 5 hours ago
Select United flight, departing Mon, Mar 16 from Indianapolis to Panama City, returning Tue, Mar 24, priced at $499 found 5 hours ago
United
Thu, Mar 19 - Wed, Mar 25
IND
Indianapolis
PTY
Panama City
$501 Roundtrip, found 15 hours ago
$501
Roundtrip
found 15 hours ago
Select United flight, departing Thu, Mar 19 from Indianapolis to Panama City, returning Wed, Mar 25, priced at $501 found 15 hours ago
American Airlines
Thu, Jan 15 - Fri, Jan 30
IND
Indianapolis
PTY
Panama City
$501 Roundtrip, found 21 hours ago
$501
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Thu, Jan 15 from Indianapolis to Panama City, returning Fri, Jan 30, priced at $501 found 21 hours ago
Copa
Sat, Mar 21 - Sat, Mar 28
IND
Indianapolis
PTY
Panama City
$694 Roundtrip, found 20 hours ago
$694
Roundtrip
found 20 hours ago
Select Copa flight, departing Sat, Mar 21 from Indianapolis to Panama City, returning Sat, Mar 28, priced at $694 found 20 hours ago
avianca
Thu, Nov 13 - Mon, Nov 17
IND
Indianapolis
PTY
Panama City
$1,111 Roundtrip, found 12 hours ago
$1,111
Roundtrip
found 12 hours ago
Select avianca flight, departing Thu, Nov 13 from Indianapolis to Panama City, returning Mon, Nov 17, priced at $1,111 found 12 hours ago

Find the cheapest month to fly from Indianapolis (IND) to Panama City (PTY)

October is typically the cheapest month to fly

From $403 - $1,501 per traveler.

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $554
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $554

Frequently asked questions

How much does a flight from Indianapolis Intl. Airport (IND) to Tocumen Intl. Airport (PTY) cost?
Get a cheap one-way flight from $232 or cheap return flight from $490 from Indianapolis Intl. Airport (IND) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Indianapolis Intl. Airport (IND) to Tocumen Intl. Airport (PTY)?
The cheapest month to fly from IND to PTY is April, when demand is low. Off-peak months are generally when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Indianapolis Intl. Airport (IND) to Tocumen Intl. Airport (PTY)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find the carrier with the cheapest IND to PTY flight.
How many flights per day from Indianapolis Intl. Airport (IND) to Tocumen Intl. Airport (PTY)?
There aren't any daily direct flights departing from Indianapolis Intl. Airport (IND) to Tocumen Intl. Airport (PTY). But you can book flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be soaring above the clouds in no time.
What day of the week has the most flights from IND to PTY?
You'll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Indianapolis Intl. Airport (IND) to Tocumen Intl. Airport (PTY)?
Choose a flight from Indianapolis Intl. Airport (IND) to Tocumen Intl. Airport (PTY) that leaves before 3 PM to reduce the risk of cancellations and delays. Departures after this hour have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Indianapolis Intl. Airport (IND) to Tocumen Intl. Airport (PTY) last-minute?
Holding off until just before your trip to book a ticket from IND to PTY often results in higher prices. While you may find some last-minute deals, they aren't always guaranteed. Keep your travel schedule open for a better chance of getting a bargain.
Is it cheaper to book an IND to PTY flight and hotel package?
Securing an IND to PTY flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Choose from our impressive range of accommodations and then add car rentals, activities and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Indianapolis Intl. Airport (IND) to Tocumen Intl. Airport (PTY)?
In most instances, you're able to cancel or reschedule your IND to PTY flight. However, there may be additional charges, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you want more information, visit our Customer Service portal.

Travel information

Origin airport
Indianapolis Intl.
Destination airport
Tocumen Intl.
Airlines serving
American Airlines, Copa, Delta, United, avianca
Roundtrip price
$489
Distance
2159 mi

Book with confidence

Indianapolis to Panama City Flights

The cheapest times to fly from Indianapolis to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Indianapolis to Panama City are during the month of April. You can find some of the cheapest flights from Indianapolis to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Indianapolis to Panama City

Sunday is one of the best days to book for cheap flights from Indianapolis to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Indianapolis to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Indianapolis to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $232 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Indianapolis to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Indianapolis to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Indianapolis to Panama City Flights

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*Available to One Key members.