
Popular airlines from Orlando Intl. Airport (MCO) to Santiago Intl. Airport (SCL)
- LATAM Airlines Group
LATAM Airlines Group
- Avianca
Avianca
- Copa
Copa
- Delta
Delta
- Air Canada
Air Canada
- American Airlines
American Airlines
- United
United
- Plan, book, fly with confidence
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Cheap Flights from Orlando to Santiago (MCO-SCL)
Prices were available within the past 7 days and start at $242 for one-way flights and $479 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.










Find the cheapest month to fly from Orlando (MCO) to Santiago (SCL)
May is typically the cheapest month to fly
Graph displaying average flight prices per month
Alternative airports near Santiago
Prices were available within the past 7 days. Prices and availability are subject to change.
Origin airport | Orlando Intl. |
Destination airport | Arturo Merino Benitez |
Airlines serving | Aeromexico, Air Canada, American Airlines, Copa, Delta, LATAM Airlines Group, United, avianca |
Roundtrip price | $479 |
Distance | 4326 mi |
Average flight time | 6 hours 30 mins |
Orlando to Santiago Flights
The cheapest times to fly from Orlando to Santiago
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Orlando to Santiago are during the month of August. You can find some of the cheapest flights from Orlando to Santiago with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Orlando to Santiago
Sunday is one of the best days to book for cheap flights from Orlando to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Orlando to Santiago
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Orlando to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $242 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Orlando to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Orlando to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
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Top Routes from Orlando
- Orlando to Chicago (MCO - ORD)
- Orlando to Newark Liberty Intl. Airport (MCO - EWR)
- Orlando to Santo Domingo (MCO - SDQ)
- Orlando to Los Angeles (MCO - LAX)
- Orlando to Newburgh (MCO - SWF)
- Orlando to Punta Cana (MCO - PUJ)
- Orlando to New York (MCO - LGA)
- Orlando to Boston (MCO - BOS)
- Orlando to Denver (MCO - DEN)
- Orlando to New York (MCO - JFK)
- Orlando to Trenton (MCO - TTN)
- Orlando to Houston (MCO - IAH)
Top Routes to Santiago
- Chicago to Santiago (ORD - SCL)
- Newark Liberty Intl. Airport to Santiago (EWR - SCL)
- Los Angeles to Santiago (LAX - SCL)
- Washington to Santiago (DCA - SCL)
- Miami to Santiago (MIA - SCL)
- New York to Santiago (LGA - SCL)
- Boston to Santiago (BOS - SCL)
- Fort Lauderdale to Santiago (FLL - SCL)
- São Paulo to Santiago (GRU - SCL)
- Buenos Aires to Santiago (AEP - SCL)
- Washington to Santiago (IAD - SCL)
- New York to Santiago (JFK - SCL)
Top Routes from Orlando
- Spirit Airlines Orlando to Chicago
- JetBlue Airways Orlando to Newark Liberty Intl. Airport
- JetBlue Airways Orlando to Santo Domingo
- Spirit Airlines Orlando to Los Angeles
- JetBlue Airways Orlando to Punta Cana
- JetBlue Airways Orlando to New York
- JetBlue Airways Orlando to Boston
- Frontier Airlines Orlando to Denver
- JetBlue Airways Orlando to New York
- Frontier Airlines Orlando to Trenton
Top Flight Destinations
- Flights to Santiago
- Flights to San Pedro de Atacama
- Flights to Torres del Paine
- Flights to Vina del Mar
- Flights to Puerto Varas
- Flights to Valle Nevado
- Flights to Hanga Roa
- Flights to Calama
- Flights to Natales
- Flights to Punta Arenas
- Flights to Pucón
- Flights to Antofagasta
- Flights to Valparaiso
- Flights to Concepción
- Flights to Puerto Montt
- Flights to Iquique
- Flights to Farellones
- Flights to La Serena
- Flights to Temuco
- Flights to San José de Maipo
Nearby Airports
- Kissimmee Gateway Airport (ISM)
- Orlando Sanford Intl. Airport (SFB)
- Leesburg Intl. Airport (LEE)
- Orlando Melbourne Intl. Airport (MLB)
- Lakeland Intl. Airport Airport (LAL)
- Daytona Beach Intl. Airport (DAB)
- Avon Park Executive Airport (AVO)
- Sebring Regional Airport (SEF)
- Vero Beach Municipal Airport (VRB)
- Peter O. Knight Airport (TPF)
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