$151 Cheap Flights from McAllen (MFE) to Buffalo (BUF)

View $151 flight on Wed, Apr 15, 2026Opens in a new window

Popular airlines from Miller Intl. Airport (MFE) to Buffalo Niagara Intl. Airport (BUF)

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Cheap Flights from McAllen to Buffalo (MFE-BUF)

Prices were available within the past 7 days and start at $151 for one-way flights and $350 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Fri, Apr 24 - Mon, Apr 27
MFE
McAllen
BUF
Buffalo
$350 Roundtrip, found 3 days ago
$350
Roundtrip
found 3 days ago
Select Delta flight, departing Fri, Apr 24 from McAllen to Buffalo, returning Mon, Apr 27, priced at $350 found 3 days ago
American Airlines
Thu, Apr 23 - Mon, Apr 27
MFE
McAllen
BUF
Buffalo
$354 Roundtrip, found 4 days ago
$354
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Apr 23 from McAllen to Buffalo, returning Mon, Apr 27, priced at $354 found 4 days ago
American Airlines
Tue, Aug 18 - Tue, Aug 25
MFE
McAllen
BUF
Buffalo
$368 Roundtrip, found 5 days ago
$368
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Aug 18 from McAllen to Buffalo, returning Tue, Aug 25, priced at $368 found 5 days ago
American Airlines
Sat, Oct 17 - Sat, Oct 24
MFE
McAllen
BUF
Buffalo
$369 Roundtrip, found 5 hours ago
$369
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sat, Oct 17 from McAllen to Buffalo, returning Sat, Oct 24, priced at $369 found 5 hours ago
American Airlines
Fri, Apr 24 - Sat, Apr 25
MFE
McAllen
BUF
Buffalo
$374 Roundtrip, found 3 days ago
$374
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Apr 24 from McAllen to Buffalo, returning Sat, Apr 25, priced at $374 found 3 days ago
Delta
Sat, Oct 17 - Sat, Oct 24
MFE
McAllen
BUF
Buffalo
$379 Roundtrip, found 5 hours ago
$379
Roundtrip
found 5 hours ago
Select Delta flight, departing Sat, Oct 17 from McAllen to Buffalo, returning Sat, Oct 24, priced at $379 found 5 hours ago
Delta
Fri, Apr 24 - Mon, Apr 27
MFE
McAllen
BUF
Buffalo
$385 Roundtrip, found 3 days ago
$385
Roundtrip
found 3 days ago
Select Delta flight, departing Fri, Apr 24 from McAllen to Buffalo, returning Mon, Apr 27, priced at $385 found 3 days ago
American Airlines
Fri, Apr 24 - Mon, Apr 27
MFE
McAllen
BUF
Buffalo
$385 Roundtrip, found 3 days ago
$385
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Apr 24 from McAllen to Buffalo, returning Mon, Apr 27, priced at $385 found 3 days ago
American Airlines
Thu, Apr 2 - Wed, Apr 8
MFE
McAllen
BUF
Buffalo
$393 Roundtrip, found 4 days ago
$393
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Apr 2 from McAllen to Buffalo, returning Wed, Apr 8, priced at $393 found 4 days ago
United
Tue, Aug 18 - Tue, Aug 25
MFE
McAllen
BUF
Buffalo
$404 Roundtrip, found 5 days ago
$404
Roundtrip
found 5 days ago
Select United flight, departing Tue, Aug 18 from McAllen to Buffalo, returning Tue, Aug 25, priced at $404 found 5 days ago

Find the cheapest month to fly from McAllen (MFE) to Buffalo (BUF)

October is typically the cheapest month to fly

From $268 - $603 per traveler.

Frequently asked questions

How much does a flight from McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) cost?
You can find cheap one-way flights from $151 and cheap return flights from $350 McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) with Expedia. One-way flights typically cost between $249 and $1237, and return flights often range between $432 and $1403. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The cheapest month to fly from MFE to BUF is April when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Enter MFE to BUF and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
To find a cheap flight from McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The earliest flight from McAllen (MFE) to Buffalo (BUF) usually leaves at around 5:00 AM, operated by American Airlines. This service is seasonal, active in June and July, allowing you to start your travel day early. An early flight can help you maximize your time in Buffalo. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The most popular departure times for flights from McAllen, TX (MFE) to Buffalo, NY (BUF) are in the early morning, from 3am to 6am. About 24% of passengers prefer this time window. Many major carriers, including United Airlines, Delta and American Airlines, offer flights during this window. This timing works well because it allows travelers to arrive in Buffalo with a full day ahead of them.
How long does it take to fly from McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Flights from MFE to BUF with one stop typically take around 5 hours 30 minutes, covering approximately 1,596 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
First class seats are offered on the MFE to BUF route. First class cabins are available on:

  • Delta Air Lines
  • American Airlines
  • United Airlines

How do I earn miles on a McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight with Expedia?
It's easy to earn miles on a McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Buffalo from Miller Intl. (MFE)?
If you're planning to travel to Buffalo from Miller Intl. (MFE), you can fly into Buffalo Niagara Intl. (BUF) Some flights may connect through major hubs like George Bush Intercontinental (IAH), Dallas-Fort Worth Intl. (DFW), Austin-Bergstrom Intl. (AUS) before reaching Buffalo. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) at the last minute?
Typically, booking a last minute flight from McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package?
Securing a McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) Buffalo Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
If you booked your McAllen, TX (MFE-Miller Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Miller Intl.
Destination airport
Buffalo Niagara Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$350
Distance
1595 mi

Book with confidence

McAllen to Buffalo Flights

The cheapest times to fly from McAllen to Buffalo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from McAllen to Buffalo are during the month of April. You can find some of the cheapest flights from McAllen to Buffalo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from McAllen to Buffalo

Sunday is one of the best days to book for cheap flights from McAllen to Buffalo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from McAllen to Buffalo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from McAllen to Buffalo in 2026. You can also book with separate airlines for your outbound and return journeys, from $151 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap McAllen to Buffalo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your McAllen to Buffalo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

McAllen to Buffalo Flights

*Flight schedules are subject to change.

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*Available to One Key members.