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$671 Cheap Flights from Panama City (PTY) to Lisbon (LIS)

View $671 flight on Wed, Apr 7, 2027Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Humberto Delgado Airport (LIS)

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Cheap Flights from Panama City to Lisbon (PTY-LIS)

Prices were available within the past 7 days and start at $671 for one-way flights and $882 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Europa
Wed, Apr 7 - Wed, Apr 21
PTY
Panama City
LIS
Lisbon
$882 Roundtrip, found 2 days ago
$882
Roundtrip
found 2 days ago
Select Air Europa flight, departing Wed, Apr 7 from Panama City to Lisbon, returning Wed, Apr 21, priced at $882 found 2 days ago
Iberia
Wed, Apr 7 - Wed, Apr 21
PTY
Panama City
LIS
Lisbon
$884 Roundtrip, found 2 days ago
$884
Roundtrip
found 2 days ago
Select Iberia flight, departing Wed, Apr 7 from Panama City to Lisbon, returning Wed, Apr 21, priced at $884 found 2 days ago
Air Europa
Wed, Apr 7 - Wed, Apr 21
PTY
Panama City
LIS
Lisbon
$891 Roundtrip, found 2 days ago
$891
Roundtrip
found 2 days ago
Select Air Europa flight, departing Wed, Apr 7 from Panama City to Lisbon, returning Wed, Apr 21, priced at $891 found 2 days ago
Iberia
Wed, Apr 7 - Wed, Apr 21
PTY
Panama City
LIS
Lisbon
$893 Roundtrip, found 2 days ago
$893
Roundtrip
found 2 days ago
Select Iberia flight, departing Wed, Apr 7 from Panama City to Lisbon, returning Wed, Apr 21, priced at $893 found 2 days ago
Air Europa
Wed, Apr 7 - Wed, Apr 21
PTY
Panama City
LIS
Lisbon
$893 Roundtrip, found 2 days ago
$893
Roundtrip
found 2 days ago
Select Air Europa flight, departing Wed, Apr 7 from Panama City to Lisbon, returning Wed, Apr 21, priced at $893 found 2 days ago
Air Europa
Wed, Apr 7 - Wed, Apr 21
PTY
Panama City
LIS
Lisbon
$902 Roundtrip, found 2 days ago
$902
Roundtrip
found 2 days ago
Select Air Europa flight, departing Wed, Apr 7 from Panama City to Lisbon, returning Wed, Apr 21, priced at $902 found 2 days ago
Iberia
Wed, Nov 11 - Tue, Nov 17
PTY
Panama City
LIS
Lisbon
$905 Roundtrip, found 6 days ago
$905
Roundtrip
found 6 days ago
Select Iberia flight, departing Wed, Nov 11 from Panama City to Lisbon, returning Tue, Nov 17, priced at $905 found 6 days ago
avianca
Sun, Jan 24 - Sat, Jan 30
PTY
Panama City
LIS
Lisbon
$922 Roundtrip, found 5 days ago
$922
Roundtrip
found 5 days ago
Select avianca flight, departing Sun, Jan 24 from Panama City to Lisbon, returning Sat, Jan 30, priced at $922 found 5 days ago
Turkish Airlines
Mon, Sep 14 - Thu, Oct 22
PTY
Panama City
LIS
Lisbon
$962 Roundtrip, found 5 days ago
$962
Roundtrip
found 5 days ago
Select Turkish Airlines flight, departing Mon, Sep 14 from Panama City to Lisbon, returning Thu, Oct 22, priced at $962 found 5 days ago
Air France
Fri, Nov 6 - Sun, Nov 15
PTY
Panama City
LIS
Lisbon
$986 Roundtrip, found 4 days ago
$986
Roundtrip
found 4 days ago
Select Air France flight, departing Fri, Nov 6 from Panama City to Lisbon, returning Sun, Nov 15, priced at $986 found 4 days ago

Alternative airports near Lisbon

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Humberto Delgado LIS. Cheapest option available. Flights from $1,310
LIS
Humberto Delgado
Cheapest
Flights from $1,310

Find the cheapest month to fly from Panama City (PTY) to Lisbon (LIS)

October is typically the cheapest month to fly

From $689 - $864 per traveler.

What you need to know for your flight from Tocumen Intl. to Humberto Delgado

Panama City (PTY) to Lisbon (LIS) at a glance

Embark on an exciting journey from Panama City (PTY) to Lisbon (LIS) with a selection of airlines catering to this international long-haul route. Evaluate various options from full-service carriers to discover the itinerary that perfectly aligns with your budget, schedule, and travel aspirations as you delve into Lisbon's iconic attractions and neighborhoods. Get the essential details for flights departing from Tocumen International Airport (PTY) to Humberto Delgado Airport (LIS).

  • Fastest flight duration: around 11h 15m in-flight, plus roughly 1h 45m layover with one stop
  • Route distance: roughly 4,800 miles (7,720 km)
  • Flights per week: around 7 departures on average
  • Typical fares (one-way): economy tickets often range from $385–$1185, depending on seasonality and how far ahead you book

Flights from Tocumen International Airport (PTY) to Humberto Delgado Airport (LIS)

Based on the latest traveler bookings, here are the top airlines favored for flights from Panama City to Lisbon, often selected for their one-stop services. Common layover points include Adolfo Suárez Madrid-Barajas Airport (MAD) with a layover of approximately 1 hour and 45 minutes, Schiphol Airport (AMS) at about 1 hour and 30 minutes, and Roissy-Charles de Gaulle Airport (CDG) with a longer layover of around 3 hours. These options allow you to balance price, total travel time, and cabin class to create your ideal itinerary.

  • Air Europa: This full-service airline provides one-stop flights, dominating the route with around 75% of departures. One-way ticket prices generally fall between $385 and $1810. Expect an in-flight duration of 11 hours and 15 minutes, with a total travel time, including layover, of approximately 12 hours and 45 minutes.
  • KLM: Representing about 11% of departures, this full-service carrier also offers one-stop services, with one-way fares usually ranging from $750 to $2375. Travelers can anticipate an in-flight time of 11 hours and 15 minutes, culminating in a total journey time of nearly 12 hours and 45 minutes when accounting for layovers.
  • Air France: Another full-service option, Air France accounts for about 4% of departures, providing one-stop services with one-way fares typically priced at $425. The in-flight experience lasts approximately 11 hours and 15 minutes, leading to a total travel time of around 12 hours and 45 minutes, including layover.

How to find the best prices for flights from Panama City (PTY) to Lisbon (LIS)

Getting some of the best deals on flights from Panama City to Lisbon is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking at least two months in advance, although most travelers tend to book between two to eight weeks ahead. Evening departures from 6 PM to 12 AM often offer lower prices and are also the most popular times to fly. Additionally, flying on Sunday generally yields cheaper rates, despite Saturday being the busiest travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Lisbon hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Humberto Delgado Airport from Tocumen International Airport

Lisbon welcomes travelers from Panama City with a range of transport options based on price, convenience, and proximity. For departures, Tocumen International Airport is roughly a 20-minute drive (covering about 15 miles) from central Panama City. Here's how to reach Lisbon efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Lisbon, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Humberto Delgado Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Humberto Delgado Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Humberto Delgado Airport, travelers will find Lisbon Airport Station, a metro station, just a short 0.1-mile walk away, while Oriente Bus Station, a bus station, is located about 1.8 miles from the airport by car. Additionally, Roma-Areeiro Station, a train station, is also approximately 1.8 miles away by car.

Frequently asked questions

How much does a flight from Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado) cost?
You can find cheap one-way flights from $671 and cheap return flights from $882 Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado) with Expedia. One-way flights generally range between $696 and $4030, and roundtrip flights usually range from $1041 to $4549. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado)?
The cheapest month to fly from PTY to LIS is April when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado)?
Enter PTY to LIS and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado)?
To find a cheap flight from Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado)?
The earliest flight from Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado) typically departs at around 2:55 AM, operated by Avianca and TAP Portugal. This is a seasonal service active in December, making it a great option if you're planning a winter getaway. An early departure like this allows you to maximize your time in Lisbon upon arrival. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado)?
The most popular departure times for flights from Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado) are in the late morning, from 9am to noon. About 34% of passengers prefer this time window. Many major carriers, including United Airlines, Copa Airlines and Avianca, offer flights during this window. This timing is favored because it allows you to enjoy a leisurely morning before heading to the airport.
How long does it take to fly from Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado)?
Flights from PTY to LIS with one stop typically take around 17 hours 20 minutes, covering approximately 4,766 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado)?
Business class is available on flights from PTY to LIS. Airlines that offer business class service on this route include:

  • Copa
  • Air Europa
  • Iberia
  • Avianca
  • Turkish Airlines
  • KLM
  • United Airlines
  • Delta Air Lines
  • American Airlines

First class is available with Iberia.
How do I earn miles on a Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado) flight with Expedia?
It's easy to earn miles on a Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Lisbon from Tocumen Intl. (PTY)?
From Tocumen Intl. (PTY), you can fly into Humberto Delgado (LIS) to reach Lisbon. Some flights may connect through major hubs like El Dorado Intl. (BOG), Liberty Intl. (EWR), Orlando Intl. (MCO) before reaching Lisbon. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado) at the last minute?
Typically, booking a last minute flight from Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado) flight and hotel package?
Securing a Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado) Lisbon Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado)?
If you booked your Panama City (PTY-Tocumen Intl.) to Lisbon (LIS-Humberto Delgado) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Tocumen Intl.
Destination airport
Humberto Delgado
Airlines serving
Air Europa, Air France, American Airlines, Delta, Iberia, KLM, Lufthansa, Turkish Airlines, United
Roundtrip price
$882
Distance
4765 mi

Book with confidence

Panama City to Lisbon Flights

The cheapest times to fly from Panama City to Lisbon

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Lisbon are during the month of April. You can find some of the cheapest flights from Panama City to Lisbon with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Lisbon

Sunday is one of the best days to book for cheap flights from Panama City to Lisbon: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Lisbon

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Lisbon in 2026. You can also book with separate airlines for your outbound and return journeys, from $671 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Lisbon flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Lisbon airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Panama City to Lisbon Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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