$275 Cheap Flights from Raleigh (RDU) to Panama City (PTY)

View $275 flight on Sat, Aug 23, 2025Opens in a new window

Popular airlines from Raleigh-Durham International Airport (RDU) to Tocumen Intl. Airport (PTY)

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Cheap Flights from Raleigh to Panama City (RDU-PTY)

Prices were available within the past 7 days and start at $275 for one-way flights and $353 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Wed, Sep 3 - Sun, Sep 14
RDU
Raleigh
PTY
Panama City
$353 Roundtrip, found 9 hours ago
$353
Roundtrip
found 9 hours ago
Select Copa flight, departing Wed, Sep 3 from Raleigh to Panama City, returning Sun, Sep 14, priced at $353 found 9 hours ago
American Airlines
Sun, Sep 28 - Sun, Oct 12
RDU
Raleigh
PTY
Panama City
$372 Roundtrip, found 9 hours ago
$372
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Sun, Sep 28 from Raleigh to Panama City, returning Sun, Oct 12, priced at $372 found 9 hours ago
American Airlines
Wed, Sep 3 - Sun, Sep 14
RDU
Raleigh
PTY
Panama City
$377 Roundtrip, found 9 hours ago
$377
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Wed, Sep 3 from Raleigh to Panama City, returning Sun, Sep 14, priced at $377 found 9 hours ago
American Airlines
Wed, Sep 24 - Sun, Sep 28
RDU
Raleigh
PTY
Panama City
$383 Roundtrip, found 3 days ago
$383
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Sep 24 from Raleigh to Panama City, returning Sun, Sep 28, priced at $383 found 3 days ago
American Airlines
Wed, Sep 3 - Sun, Sep 14
RDU
Raleigh
PTY
Panama City
$385 Roundtrip, found 9 hours ago
$385
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Wed, Sep 3 from Raleigh to Panama City, returning Sun, Sep 14, priced at $385 found 9 hours ago
American Airlines
Wed, Sep 3 - Sun, Sep 14
RDU
Raleigh
PTY
Panama City
$389 Roundtrip, found 9 hours ago
$389
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Wed, Sep 3 from Raleigh to Panama City, returning Sun, Sep 14, priced at $389 found 9 hours ago
American Airlines
Wed, Oct 1 - Sun, Oct 5
RDU
Raleigh
PTY
Panama City
$391 Roundtrip, found 3 days ago
$391
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Oct 1 from Raleigh to Panama City, returning Sun, Oct 5, priced at $391 found 3 days ago
American Airlines
Wed, Sep 24 - Sun, Sep 28
RDU
Raleigh
PTY
Panama City
$391 Roundtrip, found 3 days ago
$391
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Sep 24 from Raleigh to Panama City, returning Sun, Sep 28, priced at $391 found 3 days ago
Delta
Mon, Sep 29 - Mon, Nov 17
RDU
Raleigh
PTY
Panama City
$515 Roundtrip, just found
$515
Roundtrip
just found
Select Delta flight, departing Mon, Sep 29 from Raleigh to Panama City, returning Mon, Nov 17, priced at $515 just found
United
Mon, Sep 29 - Mon, Nov 17
RDU
Raleigh
PTY
Panama City
$515 Roundtrip, just found
$515
Roundtrip
just found
Select United flight, departing Mon, Sep 29 from Raleigh to Panama City, returning Mon, Nov 17, priced at $515 just found

Find the cheapest month to fly from Raleigh (RDU) to Panama City (PTY)

May is typically the cheapest month to fly

From $249 - $761 per traveler.

Graph displaying average flight prices per month

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $610
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $610
Flights from Raleigh (RDU) to Panama City (PTY)
Origin airport
Raleigh - Durham Intl.
Destination airport
Tocumen Intl.
Airlines serving
American Airlines, Copa, Delta, United
Roundtrip price
$352
Distance
1852 mi

Raleigh to Panama City Flights

The cheapest times to fly from Raleigh to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Raleigh to Panama City are during the month of September. You can find some of the cheapest flights from Raleigh to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Raleigh to Panama City

Sunday is one of the best days to book for cheap flights from Raleigh to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Raleigh to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Raleigh to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $275 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Raleigh to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Raleigh to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Raleigh - Durham Intl. Airport (RDU) to Tocumen Intl. Airport (PTY) cost?
You'll find cheap return flights from Raleigh - Durham Intl. Airport (RDU) to Tocumen Intl. Airport (PTY) starting at $353. Book a seat and start your adventure. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Copa flight leaving RDU on August 18 2025 and touching down at PTY. The price was last updated on July 23 2025 and has not changed since.
What is the cheapest month to fly from RDU to PTY?
The cheapest flights from RDU to PTY are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Raleigh - Durham Intl. Airport (RDU) to Tocumen Intl. Airport (PTY)?
Fly directly from Raleigh - Durham Intl. Airport (RDU) to Tocumen Intl. Airport (PTY) on a Copa Airlines flight.
What is the cheapest airline that flies from RDU to PTY?
Right now, the cheapest airline offering one-way flights from RDU to PTY is Copa. You can jet off on this route from $700. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from RDU on October 8 2025. Prices were last updated on July 23 2025 and have not changed since.
How many flights per day from Raleigh - Durham Intl. Airport (RDU) to Tocumen Intl. Airport (PTY)?
On average, Raleigh - Durham Intl. Airport (RDU) has 4 nonstop flights to Tocumen Intl. Airport (PTY) weekly. For more choice, use Expedia's filters to find flights with layovers. Squeeze in a visit to another location or simply break up your travels.
What are the most popular departure times for flights from Raleigh - Durham Intl. Airport (RDU) to Tocumen Intl. Airport (PTY)?
The 3 PM departures from RDU to PTY are the top choice for many travelers. They can also be more expensive. If you want to save money, book during off-peak hours.
What day of the week has the most flights from RDU to PTY?
Wednesday has the most flights from Raleigh - Durham Intl. Airport (RDU) to Tocumen Intl. Airport (PTY). Consider leaving on this day and you'll have a greater chance of finding a departure that fits your schedule.
What is the earliest flight from Raleigh - Durham Intl. Airport (RDU) to Tocumen Intl. Airport (PTY)?
Catch the earliest flight at around 3:11PM UTC-5, departing from Raleigh - Durham Intl. Airport (RDU). You'll be in the air for around 4h 35m, touching down at Tocumen Intl. Airport (PTY) at approximately 7:46PM UTC-5.
How long does it take to fly from Raleigh - Durham Intl. Airport (RDU) to Tocumen Intl. Airport (PTY)?
Flights from RDU to PTY have an average travel time of 4 hours and 35 minutes. The distance between the two is 1,850 mi.
What is the best time to fly from Raleigh - Durham Intl. Airport (RDU) to Tocumen Intl. Airport (PTY)?
To land at Tocumen Intl. Airport (PTY) on time, choose a flight that takes off from Raleigh - Durham Intl. Airport (RDU) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Panama City from Raleigh - Durham Intl. Airport (RDU)?
If you're flying on a direct flight from Raleigh - Durham Intl. Airport (RDU) to Panama City, Tocumen Intl. Airport (PTY) is the only airport you can touch down at.
Is it cheaper to buy a plane ticket from Raleigh - Durham Intl. Airport (RDU) to Tocumen Intl. Airport (PTY) last-minute?
Holding off until right before your break to book a ticket from RDU to PTY often results in higher prices. While you may find some last-minute offers, there's no guarantee. Keep your travel plans flexible for a better chance of getting a bargain.
Is it cheaper to book a RDU to PTY flight and hotel package?
Securing a RDU to PTY flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip in one place. Pick from our wide range of accommodations and then add activities, car rentals and flights to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Raleigh - Durham Intl. Airport (RDU) to Tocumen Intl. Airport (PTY)?
In most instances, you can cancel or reschedule your RDU to PTY flight. However, there may be additional charges, especially if you booked over 24 hours ago. Check your itinerary for the airline's guidelines and fees on flight changes, or if you'd like further details, go to our Customer Service portal.

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