$253 Cheap Flights from Santo Domingo (SDQ) to Panama City (PTY)

View $253 flight on Tue, Dec 2, 2025Opens in a new window

Popular airlines from Las Americas Intl. Airport (SDQ) to Tocumen Intl. Airport (PTY)

Cheap Flights from Santo Domingo to Panama City (SDQ-PTY)

Prices were available within the past 7 days and start at $253 for one-way flights and $525 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Tue, Dec 2 - Tue, Dec 9
SDQ
Santo Domingo
PTY
Panama City
$525 Roundtrip, just found
$525
Roundtrip
just found
Select Copa flight, departing Tue, Dec 2 from Santo Domingo to Panama City, returning Tue, Dec 9, priced at $525 just found
American Airlines
Wed, Nov 5 - Thu, Nov 6
SDQ
Santo Domingo
PTY
Panama City
$536 Roundtrip, found 5 hours ago
$536
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Wed, Nov 5 from Santo Domingo to Panama City, returning Thu, Nov 6, priced at $536 found 5 hours ago
Copa
Tue, Dec 2 - Tue, Dec 9
SDQ
Santo Domingo
PTY
Panama City
$536 Roundtrip, just found
$536
Roundtrip
just found
Select Copa flight, departing Tue, Dec 2 from Santo Domingo to Panama City, returning Tue, Dec 9, priced at $536 just found
American Airlines
Fri, Nov 7 - Sat, Nov 15
SDQ
Santo Domingo
PTY
Panama City
$542 Roundtrip, found 7 hours ago
$542
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Fri, Nov 7 from Santo Domingo to Panama City, returning Sat, Nov 15, priced at $542 found 7 hours ago
Copa
Wed, Nov 19 - Sun, Nov 23
SDQ
Santo Domingo
PTY
Panama City
$543 Roundtrip, found 4 hours ago
$543
Roundtrip
found 4 hours ago
Select Copa flight, departing Wed, Nov 19 from Santo Domingo to Panama City, returning Sun, Nov 23, priced at $543 found 4 hours ago
American Airlines
Sun, Nov 9 - Wed, Nov 12
SDQ
Santo Domingo
PTY
Panama City
$548 Roundtrip, found 1 hour ago
$548
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Sun, Nov 9 from Santo Domingo to Panama City, returning Wed, Nov 12, priced at $548 found 1 hour ago
avianca
Tue, Dec 2 - Tue, Dec 9
SDQ
Santo Domingo
PTY
Panama City
$548 Roundtrip, just found
$548
Roundtrip
just found
Select avianca flight, departing Tue, Dec 2 from Santo Domingo to Panama City, returning Tue, Dec 9, priced at $548 just found
American Airlines
Tue, Dec 2 - Tue, Dec 9
SDQ
Santo Domingo
PTY
Panama City
$551 Roundtrip, just found
$551
Roundtrip
just found
Select American Airlines flight, departing Tue, Dec 2 from Santo Domingo to Panama City, returning Tue, Dec 9, priced at $551 just found
Copa
Wed, Nov 19 - Sun, Nov 23
SDQ
Santo Domingo
PTY
Panama City
$555 Roundtrip, found 4 hours ago
$555
Roundtrip
found 4 hours ago
Select Copa flight, departing Wed, Nov 19 from Santo Domingo to Panama City, returning Sun, Nov 23, priced at $555 found 4 hours ago
Aeromexico
Fri, Nov 28 - Wed, Dec 10
SDQ
Santo Domingo
PTY
Panama City
$659 Roundtrip, found 1 day ago
$659
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Fri, Nov 28 from Santo Domingo to Panama City, returning Wed, Dec 10, priced at $659 found 1 day ago

Find the cheapest month to fly from Santo Domingo (SDQ) to Panama City (PTY)

May is typically the cheapest month to fly

From $361 - $548 per traveler.

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $525
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $525
Flights from Santo Domingo (SDQ) to Panama City (PTY)
Origin airport
Las Americas Intl.
Destination airport
Tocumen Intl.
Airlines serving
Aeromexico, American Airlines, Copa, United, avianca
Roundtrip price
$524
Distance
917 mi
Average flight time
1 hour 33 mins

Santo Domingo to Panama City Flights

The cheapest times to fly from Santo Domingo to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santo Domingo to Panama City are during the month of December. You can find some of the cheapest flights from Santo Domingo to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santo Domingo to Panama City

Sunday is one of the best days to book for cheap flights from Santo Domingo to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santo Domingo to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santo Domingo to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $253 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santo Domingo to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santo Domingo to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Las Americas Intl. Airport (SDQ) to Tocumen Intl. Airport (PTY) cost?
Grab a cheap one-way flight from $253 or cheap return flight from $525 from Las Americas Intl. Airport (SDQ) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Las Americas Intl. Airport (SDQ) to Tocumen Intl. Airport (PTY)?
The cheapest month to fly from SDQ to PTY is December, when there's less demand. Off-peak season is generally when airlines offer lower prices between these airports.
Which airlines fly direct from Las Americas Intl. Airport (SDQ) to Tocumen Intl. Airport (PTY)?
Take a direct flight with Copa Airlines and journey straight from Las Americas Intl. Airport (SDQ) to Tocumen Intl. Airport (PTY).
What is the cheapest airline that flies from Las Americas Intl. Airport (SDQ) to Tocumen Intl. Airport (PTY)?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from SDQ to PTY. Then, sort your results by "Price (lowest to highest)" to snag the best deal available.
How many flights per day from Las Americas Intl. Airport (SDQ) to Tocumen Intl. Airport (PTY)?
Every day, an average of 4 nonstop flights take off from Las Americas Intl. Airport (SDQ) to Tocumen Intl. Airport (PTY). Choose the departure time that best suits your travel plans.
What are the most popular departure times for flights from Las Americas Intl. Airport (SDQ) to Tocumen Intl. Airport (PTY)?
More passengers fly between SDQ and PTY at 8 AM than at any other time of day. Looking to skip the crowds? Try choosing a quieter departure window and you could save on your fare as well.
What day of the week has the most flights from SDQ to PTY?
If you depart on a Sunday, you'll get the greatest range of options for flights from Las Americas Intl. Airport (SDQ) to Tocumen Intl. Airport (PTY).
What is the earliest flight from Las Americas Intl. Airport (SDQ) to Tocumen Intl. Airport (PTY)?
The first flight of the day jetting off from Las Americas Intl. Airport (SDQ) is at around 6:18AM UTC-4. Catch this flight and you'll reach Tocumen Intl. Airport (PTY) at approximately 8:00AM UTC-5. The entire trip takes 2h 42m.
How long does it take to fly from Las Americas Intl. Airport (SDQ) to Tocumen Intl. Airport (PTY)?
It takes roughly 2 hours and 39 minutes to cover the 920 mi from SDQ to PTY.
What airline has the least delays from SDQ to PTY?
Copa Airlines has the best performance for on-time direct flights from Las Americas Intl. Airport (SDQ) to Tocumen Intl. Airport (PTY), with an on-time rating of 95%. Use the Expedia App to view your flight status before you go and get real-time updates about any trip changes.
What is the best time to fly from Las Americas Intl. Airport (SDQ) to Tocumen Intl. Airport (PTY)?
To touch down at Tocumen Intl. Airport (PTY) on time, book a flight that leaves Las Americas Intl. Airport (SDQ) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Panama City from Las Americas Intl. Airport (SDQ)?
Browse your flight options from Las Americas Intl. Airport (SDQ) to Tocumen Intl. Airport (PTY). This is the only airport in Panama City you can arrive at if you're taking a direct flight.
Is it cheaper to buy a plane ticket from Las Americas Intl. Airport (SDQ) to Tocumen Intl. Airport (PTY) last-minute?
Holding off until just before your trip to book a ticket from SDQ to PTY often results in higher prices. While you may come across some last-minute discounts, there's no guarantee. Allow some flexibility in your schedule for the best chance of landing a bargain.
Is it cheaper to book a SDQ to PTY flight and hotel package?
Compared with arranging hotels and flights separately, booking a SDQ to PTY flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one convenient place will take the stress out of travel planning. Simply secure your flights and choose from our extensive range of hotels, then personalize your trip with other add-ons like car rentals and activities.
Can I cancel or change the date of my flight from Las Americas Intl. Airport (SDQ) to Tocumen Intl. Airport (PTY)?
In most instances, you're able to cancel or reschedule your SDQ to PTY flight. However, additional fees may apply, especially if your booking was made more than 24 hours ago. Double-check your itinerary for the airline's rules and fees on flight changes, or if you need more information, visit our Customer Service portal.

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*Available to One Key members.