$315 Cheap Flights from Quito (UIO) to Panama City (PTY)

View $315 flight on Thu, Jan 15, 2026Opens in a new window

Popular airlines from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY)

Cheap Flights from Quito to Panama City (UIO-PTY)

Prices were available within the past 7 days and start at $315 for one-way flights and $450 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Tue, Oct 21 - Sat, Oct 25
UIO
Quito
PTY
Panama City
$450 Roundtrip, found 1 hour ago
$450
Roundtrip
found 1 hour ago
Select Copa flight, departing Tue, Oct 21 from Quito to Panama City, returning Sat, Oct 25, priced at $450 found 1 hour ago
Copa
Tue, Oct 21 - Sat, Oct 25
UIO
Quito
PTY
Panama City
$462 Roundtrip, found 1 hour ago
$462
Roundtrip
found 1 hour ago
Select Copa flight, departing Tue, Oct 21 from Quito to Panama City, returning Sat, Oct 25, priced at $462 found 1 hour ago
Copa
Tue, Oct 21 - Sat, Oct 25
UIO
Quito
PTY
Panama City
$474 Roundtrip, found 1 hour ago
$474
Roundtrip
found 1 hour ago
Select Copa flight, departing Tue, Oct 21 from Quito to Panama City, returning Sat, Oct 25, priced at $474 found 1 hour ago
Copa
Fri, Oct 10 - Mon, Oct 13
UIO
Quito
PTY
Panama City
$486 Roundtrip, found 1 hour ago
$486
Roundtrip
found 1 hour ago
Select Copa flight, departing Fri, Oct 10 from Quito to Panama City, returning Mon, Oct 13, priced at $486 found 1 hour ago
Copa
Sat, Sep 27 - Tue, Sep 30
UIO
Quito
PTY
Panama City
$487 Roundtrip, found 5 days ago
$487
Roundtrip
found 5 days ago
Select Copa flight, departing Sat, Sep 27 from Quito to Panama City, returning Tue, Sep 30, priced at $487 found 5 days ago
Copa
Thu, Oct 2 - Sun, Oct 12
UIO
Quito
PTY
Panama City
$495 Roundtrip, found 5 days ago
$495
Roundtrip
found 5 days ago
Select Copa flight, departing Thu, Oct 2 from Quito to Panama City, returning Sun, Oct 12, priced at $495 found 5 days ago
Copa
Fri, Oct 10 - Mon, Oct 13
UIO
Quito
PTY
Panama City
$498 Roundtrip, found 1 hour ago
$498
Roundtrip
found 1 hour ago
Select Copa flight, departing Fri, Oct 10 from Quito to Panama City, returning Mon, Oct 13, priced at $498 found 1 hour ago
Copa
Fri, Sep 26 - Fri, Oct 3
UIO
Quito
PTY
Panama City
$499 Roundtrip, found 17 hours ago
$499
Roundtrip
found 17 hours ago
Select Copa flight, departing Fri, Sep 26 from Quito to Panama City, returning Fri, Oct 3, priced at $499 found 17 hours ago
Copa
Mon, Oct 20 - Thu, Oct 30
UIO
Quito
PTY
Panama City
$507 Roundtrip, just found
$507
Roundtrip
just found
Select Copa flight, departing Mon, Oct 20 from Quito to Panama City, returning Thu, Oct 30, priced at $507 just found
avianca
Sat, Sep 27 - Tue, Sep 30
UIO
Quito
PTY
Panama City
$547 Roundtrip, found 5 days ago
$547
Roundtrip
found 5 days ago
Select avianca flight, departing Sat, Sep 27 from Quito to Panama City, returning Tue, Sep 30, priced at $547 found 5 days ago

Find the cheapest month to fly from Quito (UIO) to Panama City (PTY)

February is typically the cheapest month to fly

From $294 - $653 per traveler.

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $474
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $474
Flights from Quito (UIO) to Panama City (PTY)
Origin airport
Mariscal Sucre Intl.
Destination airport
Tocumen Intl.
Airlines serving
Copa, avianca
Roundtrip price
$449
Distance
638 mi
Average flight time
1 hour 56 mins

Quito to Panama City Flights

The cheapest times to fly from Quito to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Quito to Panama City are during the month of October. You can find some of the cheapest flights from Quito to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Quito to Panama City

Sunday is one of the best days to book for cheap flights from Quito to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Quito to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Quito to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $315 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Quito to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Quito to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY) cost?
Get a cheap one-way flight from $315 or cheap return flight from $450 from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY)?
Planning your trip for October can help you save, as it's the cheapest month for flights between UIO and PTY. You'll usually find the lowest fares during off-peak months.
Which airlines fly direct from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY)?
Fly directly from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY) on a Copa Airlines flight.
What is the cheapest airline that flies from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find the carrier with the cheapest UIO to PTY flight.
How many flights per day from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY)?
When flying out of Mariscal Sucre Intl. Airport (UIO), you can choose from an average of 4 daily direct flights to Tocumen Intl. Airport (PTY).
What are the most popular departure times for flights from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY)?
The 6 AM departures from UIO to PTY are typically the busiest. Greater demand means you'll likely pay more for these departures. If you want to save money, book during off-peak hours.
What day of the week has the most flights from UIO to PTY?
If you travel on a Friday, you'll get the greatest range of options for flights from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY).
What is the earliest flight from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY)?
The earliest flight leaving Mariscal Sucre Intl. Airport (UIO) is at around 3:08AM UTC-5. Board this flight and you'll land at Tocumen Intl. Airport (PTY) at approximately 5:05AM UTC-5. The overall travel time is 1h 57m.
How long does it take to fly from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY)?
It takes approximately 1 hour and 57 minutes to cover the 640 mi from UIO to PTY.
What airline has the least delays from UIO to PTY?
Copa Airlines has the best performance for on-time direct flights from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY), with an on-time score of 96%. Use the Expedia App to check your journey status before you go and get immediate updates about any trip changes.
What is the best time to fly from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY)?
To avoid potential delays on the Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY) route, aim to fly before 3 PM. Later departures have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Panama City from Mariscal Sucre Intl. Airport (UIO)?
If you're boarding a direct flight from Mariscal Sucre Intl. Airport (UIO) to Panama City, Tocumen Intl. Airport (PTY) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY) last-minute?
Last-minute fares from UIO to PTY are usually more expensive. To secure the lowest rates, start looking for flights well in advance. That being said, if you're flexible with your travel plans, you may find a cheap ticket right before your trip.
Is it cheaper to book an UIO to PTY flight and hotel package?
Compared with arranging hotels and flights separately, booking an UIO to PTY flight and hotel package with Expedia could lead to significant savings. What's more, having it all in one place will take the hassle out of planning your trip. Just pick your flights and select from our wide range of hotels, then tailor your trip with extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY)?
Generally, it's possible to reschedule or cancel your UIO to PTY flight. However, for bookings made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find further details on our Customer Service portal.

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*Available to One Key members.