$313 Cheap Flights from Quito (UIO) to Panama City (PTY)

View $313 flight on Sat, Oct 18, 2025Opens in a new window

Popular airlines from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY)

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Cheap Flights from Quito to Panama City (UIO-PTY)

Prices were available within the past 7 days and start at $313 for one-way flights and $490 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Tue, Sep 9 - Sat, Sep 20
UIO
Quito
PTY
Panama City
$490 Roundtrip, just found
$490
Roundtrip
just found
Select Copa flight, departing Tue, Sep 9 from Quito to Panama City, returning Sat, Sep 20, priced at $490 just found
Copa
Tue, Sep 9 - Sat, Sep 20
UIO
Quito
PTY
Panama City
$494 Roundtrip, just found
$494
Roundtrip
just found
Select Copa flight, departing Tue, Sep 9 from Quito to Panama City, returning Sat, Sep 20, priced at $494 just found
Copa
Mon, Aug 18 - Fri, Aug 22
UIO
Quito
PTY
Panama City
$498 Roundtrip, just found
$498
Roundtrip
just found
Select Copa flight, departing Mon, Aug 18 from Quito to Panama City, returning Fri, Aug 22, priced at $498 just found
Copa
Tue, Sep 9 - Sat, Sep 20
UIO
Quito
PTY
Panama City
$502 Roundtrip, just found
$502
Roundtrip
just found
Select Copa flight, departing Tue, Sep 9 from Quito to Panama City, returning Sat, Sep 20, priced at $502 just found
Copa
Tue, Sep 9 - Sat, Sep 20
UIO
Quito
PTY
Panama City
$506 Roundtrip, just found
$506
Roundtrip
just found
Select Copa flight, departing Tue, Sep 9 from Quito to Panama City, returning Sat, Sep 20, priced at $506 just found
Copa
Mon, Aug 18 - Fri, Aug 22
UIO
Quito
PTY
Panama City
$510 Roundtrip, just found
$510
Roundtrip
just found
Select Copa flight, departing Mon, Aug 18 from Quito to Panama City, returning Fri, Aug 22, priced at $510 just found
Copa
Tue, Sep 9 - Sat, Sep 20
UIO
Quito
PTY
Panama City
$514 Roundtrip, just found
$514
Roundtrip
just found
Select Copa flight, departing Tue, Sep 9 from Quito to Panama City, returning Sat, Sep 20, priced at $514 just found
Copa
Tue, Sep 9 - Sat, Sep 20
UIO
Quito
PTY
Panama City
$518 Roundtrip, just found
$518
Roundtrip
just found
Select Copa flight, departing Tue, Sep 9 from Quito to Panama City, returning Sat, Sep 20, priced at $518 just found
Copa
Thu, Aug 28 - Sun, Aug 31
UIO
Quito
PTY
Panama City
$519 Roundtrip, found 13 hours ago
$519
Roundtrip
found 13 hours ago
Select Copa flight, departing Thu, Aug 28 from Quito to Panama City, returning Sun, Aug 31, priced at $519 found 13 hours ago
avianca
Sun, Aug 10 - Sat, Aug 23
UIO
Quito
PTY
Panama City
$622 Roundtrip, found 14 hours ago
$622
Roundtrip
found 14 hours ago
Select avianca flight, departing Sun, Aug 10 from Quito to Panama City, returning Sat, Aug 23, priced at $622 found 14 hours ago

Find the cheapest month to fly from Quito (UIO) to Panama City (PTY)

March is typically the cheapest month to fly

From $294 - $652 per traveler.

Graph displaying average flight prices per month

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Panama Pacifico Intl. BLB. Average driving time to city center is 16 minutes. Flights from $569
BLB
Panama Pacifico Intl.
Average driving time to city center16 min
Flights from $569
Flights from Quito (UIO) to Panama City (PTY)
Origin airport
Mariscal Sucre Intl.
Destination airport
Tocumen Intl.
Airlines serving
Copa, avianca
Roundtrip price
$490
Distance
638 mi
Average flight time
1 hour 57 mins

Quito to Panama City Flights

The cheapest times to fly from Quito to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Quito to Panama City are during the month of September. You can find some of the cheapest flights from Quito to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Quito to Panama City

Sunday is one of the best days to book for cheap flights from Quito to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Quito to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Quito to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $313 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Quito to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Quito to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY) cost?
Book cheap return tickets starting from $498 from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY). This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Copa flight leaving UIO on August 19 2025 and touching down at PTY. The price was last updated on July 23 2025 and has not changed since.
What is the cheapest month to fly from UIO to PTY?
The cheapest flights from UIO to PTY are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY)?
Fly directly from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY) on a Copa Airlines flight.
What is the cheapest airline that flies from UIO to PTY?
Fly from UIO to PTY with Copa. This carrier currently has the cheapest one-way ticket on this route, starting at $596. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from UIO on August 7 2025. Prices were last updated on July 23 2025 and have not changed since.
How many flights per day from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY)?
When flying out of Mariscal Sucre Intl. Airport (UIO), you can choose from an average of 4 daily direct flights to Tocumen Intl. Airport (PTY).
What are the most popular departure times for flights from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY)?
The 6 AM departures from UIO to PTY are typically the busiest. Greater demand means you'll likely pay more for these departures. If you want to save money, book during off-peak hours.
What day of the week has the most flights from UIO to PTY?
If you travel on a Friday, you'll get the greatest range of options for flights from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY).
What is the earliest flight from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY)?
The earliest flight leaving Mariscal Sucre Intl. Airport (UIO) is at around 3:08AM UTC-5. Board this flight and you'll land at Tocumen Intl. Airport (PTY) at approximately 5:05AM UTC-5. The overall travel time is 1h 57m.
How long does it take to fly from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY)?
It takes approximately 1 hour and 57 minutes to cover the 640 mi from UIO to PTY.
What airline has the least delays from UIO to PTY?
Copa Airlines has the best performance for on-time direct flights from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY), with an on-time score of 96%. Use the Expedia App to check your journey status before you go and get immediate updates about any trip changes.
What is the best time to fly from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY)?
To avoid potential delays on the Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY) route, aim to fly before 3 PM. Later departures have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Panama City from Mariscal Sucre Intl. Airport (UIO)?
If you're boarding a direct flight from Mariscal Sucre Intl. Airport (UIO) to Panama City, Tocumen Intl. Airport (PTY) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY) last-minute?
Last-minute fares from UIO to PTY are usually more expensive. To secure the lowest rates, start looking for flights well in advance. That being said, if you're flexible with your travel plans, you may find a cheap ticket right before your trip.
Is it cheaper to book an UIO to PTY flight and hotel package?
Compared with arranging hotels and flights separately, booking an UIO to PTY flight and hotel package with Expedia could lead to significant savings. What's more, having it all in one place will take the hassle out of planning your trip. Just pick your flights and select from our wide range of hotels, then tailor your trip with extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from Mariscal Sucre Intl. Airport (UIO) to Tocumen Intl. Airport (PTY)?
Generally, it's possible to reschedule or cancel your UIO to PTY flight. However, for bookings made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find further details on our Customer Service portal.

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Panama City nearby Airports

Balboa

Quito to Panama Pacifico Intl.
$568.07
*Available to One Key members.