$139 Cheap American Airlines flights Detroit (DTW) to Fort Myers (RSW)

Use the "Price (lowest to highest)" filter on Expedia to look for cheap American Airlines round-trip flights from $187 from DTW to RSW. Affordable one-way fares from $139 are available too.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

To find cheap American Airlines fares from Detroit Metropolitan Wayne County Airport (DTW) to Southwest Florida Intl. Airport (RSW), start searching one to three months before your intended departure. Securing domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also affect the price you pay. Sunday tends to be the cheapest, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your journey on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departures from DTW to RSW with American Airlines, filter your results by "Early Morning" and "Morning." Choosing an early flight usually means you'll experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.