$147 Cheap American Airlines flights McAllen (MFE) to Minneapolis (MSP)

Finding cheap one-way American Airlines flights from MFE to MSP from $147 on Expedia couldn’t be simpler — just filter by “Price (lowest to highest).” Alternatively, check out our budget-friendly round-trip fares from $246 for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

American Airlines flights to Minneapolis - St. Paul tend to be cheaper in the quieter months of January and February. Whether you’re after a return or one-way ticket, you could find a better deal then.

To find cheap American Airlines fares from Miller Intl. Airport (MFE) to Minneapolis - St. Paul Intl. Airport (MSP), start searching one to three months before your intended departure. Securing domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also influence the price you pay. Sunday is usually the cheapest, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your flight on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Use the “Nonstop” filter when searching for direct American Airlines flights from MFE to MSP. You can also compare other carriers servicing the same direct route.

Filter your results by “Morning” and “Early Morning” to browse the earliest departures from MFE to MSP. Heading off early means you’re 20% less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Minneapolis - St. Paul Intl. Airport (MSP) is the main Minneapolis - St. Paul hub for American Airlines flights from Miller Intl. Airport (MFE).

Depending on the ticket type you purchased, a fee may apply if you cancel or reschedule your booking more than 24 hours after it has been confirmed. To find plane tickets with more flexibility, select our “Changes included” and “No cancel fee” boxes when you look for flights. For more details on modifying or canceling your reservation, go to “Trips,” select your flight and tick “Manage Booking.”