$67 Cheap Flights from Brussels (BRU) to Santander (SDR)

View $67 flight on Tue, Sep 30, 2025Opens in a new window

Popular airlines from Brussels Airport (BRU) to Santander (SDR)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • one key icon

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Brussels to Santander (BRU-SDR)

Prices were available within the past 7 days and start at $67 for one-way flights and $123 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Vueling Airlines
Mon, Nov 17 - Tue, Dec 2
BRU
Brussels
SDR
Santander
$123 Roundtrip, found 1 day ago
$123
Roundtrip
found 1 day ago
Select Vueling Airlines flight, departing Mon, Nov 17 from Brussels to Santander, returning Tue, Dec 2, priced at $123 found 1 day ago
Vueling Airlines
Mon, Nov 17 - Tue, Dec 2
BRU
Brussels
SDR
Santander
$130 Roundtrip, found 1 day ago
$130
Roundtrip
found 1 day ago
Select Vueling Airlines flight, departing Mon, Nov 17 from Brussels to Santander, returning Tue, Dec 2, priced at $130 found 1 day ago
Vueling Airlines
Mon, Nov 17 - Tue, Dec 2
BRU
Brussels
SDR
Santander
$140 Roundtrip, found 1 day ago
$140
Roundtrip
found 1 day ago
Select Vueling Airlines flight, departing Mon, Nov 17 from Brussels to Santander, returning Tue, Dec 2, priced at $140 found 1 day ago
Vueling Airlines
Mon, Nov 17 - Tue, Dec 2
BRU
Brussels
SDR
Santander
$147 Roundtrip, found 1 day ago
$147
Roundtrip
found 1 day ago
Select Vueling Airlines flight, departing Mon, Nov 17 from Brussels to Santander, returning Tue, Dec 2, priced at $147 found 1 day ago
Iberia
Wed, Nov 5 - Sat, Nov 15
BRU
Brussels
SDR
Santander
$203 Roundtrip, found 5 days ago
$203
Roundtrip
found 5 days ago
Select Iberia flight, departing Wed, Nov 5 from Brussels to Santander, returning Sat, Nov 15, priced at $203 found 5 days ago
Iberia
Wed, Nov 5 - Sat, Nov 15
BRU
Brussels
SDR
Santander
$211 Roundtrip, found 5 days ago
$211
Roundtrip
found 5 days ago
Select Iberia flight, departing Wed, Nov 5 from Brussels to Santander, returning Sat, Nov 15, priced at $211 found 5 days ago
Iberia
Wed, Nov 5 - Sat, Nov 15
BRU
Brussels
SDR
Santander
$213 Roundtrip, found 5 days ago
$213
Roundtrip
found 5 days ago
Select Iberia flight, departing Wed, Nov 5 from Brussels to Santander, returning Sat, Nov 15, priced at $213 found 5 days ago
Iberia
Wed, Nov 5 - Sat, Nov 15
BRU
Brussels
SDR
Santander
$221 Roundtrip, found 5 days ago
$221
Roundtrip
found 5 days ago
Select Iberia flight, departing Wed, Nov 5 from Brussels to Santander, returning Sat, Nov 15, priced at $221 found 5 days ago
Iberia
Mon, Nov 17 - Tue, Dec 2
BRU
Brussels
SDR
Santander
$229 Roundtrip, found 1 day ago
$229
Roundtrip
found 1 day ago
Select Iberia flight, departing Mon, Nov 17 from Brussels to Santander, returning Tue, Dec 2, priced at $229 found 1 day ago
Iberia
Mon, Nov 17 - Tue, Dec 2
BRU
Brussels
SDR
Santander
$238 Roundtrip, found 1 day ago
$238
Roundtrip
found 1 day ago
Select Iberia flight, departing Mon, Nov 17 from Brussels to Santander, returning Tue, Dec 2, priced at $238 found 1 day ago

Frequently asked questions

How much does a flight from Brussels - National Airport (BRU) to Santander Airport (SDR) cost?
Secure a cheap one-way flight from $67 or cheap return flight from $123 from Brussels - National Airport (BRU) to Santander Airport (SDR) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Brussels - National Airport (BRU) to Santander Airport (SDR)?
The cheapest month to fly from BRU to SDR is November, when there's less demand. Off-peak season is usually when better flight deals are available between these airports.
Which airlines fly direct from Brussels - National Airport (BRU) to Santander Airport (SDR)?
You can't take a direct flight to Santander Airport (SDR) from Brussels (BRU-Brussels - National). However, you can easily journey to Santander without any layovers by taking off from Brussels South Charleroi Airport (CRL).
What is the cheapest airline that flies from Brussels - National Airport (BRU) to Santander Airport (SDR)?
Expedia's filter tool lets you easily compare different airlines, departure times and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest BRU to SDR flight.
How many flights per day from Brussels - National Airport (BRU) to Santander Airport (SDR)?
Direct flights from Brussels - National Airport (BRU) to Santander Airport (SDR) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel details and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from BRU to SDR?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Brussels - National Airport (BRU) to Santander Airport (SDR)?
To avoid possible delays on the Brussels - National Airport (BRU) to Santander Airport (SDR) route, aim to fly before 3 PM. Departures after this hour have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Santander from Brussels - National Airport (BRU)?
Explore your flight options from Brussels - National Airport (BRU) to Bilbao Airport (BIO). This is the only Santander airport you can jet into if you're taking a direct flight.
Is it cheaper to buy a plane ticket from Brussels - National Airport (BRU) to Santander Airport (SDR) last-minute?
Waiting until just before your trip to book your flight from BRU to SDR generally means paying more. While you may come across some last-minute discounts, they're not always guaranteed. Be flexible with your itinerary to maximize your chances of snagging a bargain.
Is it cheaper to book a BRU to SDR flight and hotel package?
You'll generally save money by booking a BRU to SDR flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one convenient place. After choosing your ideal flights and accommodations, consider adding extras such as activities, car rentals and tours.
Can I cancel or change the date of my flight from Brussels - National Airport (BRU) to Santander Airport (SDR)?
In most cases, you can cancel or modify your BRU to SDR flight. However, there may be additional charges, especially if your booking was made more than 24 hours ago. Double-check your itinerary for the airline's fees and policies on flight changes, or if you need more details, head to our Customer Service portal.

Travel information

Travel information

Origin airport
Brussels - National
Destination airport
Santander
Airlines serving
Iberia, Vueling Airlines
Roundtrip price
$123
Distance
646 mi

Book with confidence

Book with confidence

Brussels to Santander Flights

The cheapest times to fly from Brussels to Santander

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Brussels to Santander are during the month of November. You can find some of the cheapest flights from Brussels to Santander with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Brussels to Santander

Sunday is one of the best days to book for cheap flights from Brussels to Santander: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Brussels to Santander

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Brussels to Santander in 2025. You can also book with separate airlines for your outbound and return journeys, from $67 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Brussels to Santander flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Brussels to Santander airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Brussels to Santander Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.