$100 Cheap Flights from Buffalo (BUF) to Myrtle Beach (MYR)

View $100 flight on Sun, Aug 31, 2025Opens in a new window

Popular airlines from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR)

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Cheap Flights from Buffalo to Myrtle Beach (BUF-MYR)

Prices were available within the past 7 days and start at $100 for one-way flights and $203 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Tue, Oct 28 - Fri, Oct 31
BUF
Buffalo
MYR
Myrtle Beach
$203 Roundtrip, found 3 days ago
$203
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Tue, Oct 28 from Buffalo to Myrtle Beach, returning Fri, Oct 31, priced at $203 found 3 days ago
Southwest Airlines
Tue, Oct 28 - Fri, Oct 31
BUF
Buffalo
MYR
Myrtle Beach
$208 Roundtrip, found 3 days ago
$208
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Tue, Oct 28 from Buffalo to Myrtle Beach, returning Fri, Oct 31, priced at $208 found 3 days ago
American Airlines
Sun, Aug 31 - Wed, Sep 3
BUF
Buffalo
MYR
Myrtle Beach
$208 Roundtrip, found 2 days ago
$208
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Aug 31 from Buffalo to Myrtle Beach, returning Wed, Sep 3, priced at $208 found 2 days ago
American Airlines
Sun, Aug 31 - Wed, Sep 3
BUF
Buffalo
MYR
Myrtle Beach
$209 Roundtrip, found 2 days ago
$209
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Aug 31 from Buffalo to Myrtle Beach, returning Wed, Sep 3, priced at $209 found 2 days ago
Delta
Mon, Jun 30 - Fri, Jul 4
BUF
Buffalo
MYR
Myrtle Beach
$211 Roundtrip, found 1 day ago
$211
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Jun 30 from Buffalo to Myrtle Beach, returning Fri, Jul 4, priced at $211 found 1 day ago
Southwest Airlines
Fri, Oct 31 - Mon, Nov 3
BUF
Buffalo
MYR
Myrtle Beach
$213 Roundtrip, found 3 days ago
$213
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Fri, Oct 31 from Buffalo to Myrtle Beach, returning Mon, Nov 3, priced at $213 found 3 days ago
Southwest Airlines
Thu, Oct 2 - Mon, Oct 6
BUF
Buffalo
MYR
Myrtle Beach
$217 Roundtrip, just found
$217
Roundtrip
just found
Select Southwest Airlines flight, departing Thu, Oct 2 from Buffalo to Myrtle Beach, returning Mon, Oct 6, priced at $217 just found
Delta
Wed, Sep 24 - Tue, Sep 30
BUF
Buffalo
MYR
Myrtle Beach
$217 Roundtrip, just found
$217
Roundtrip
just found
Select Delta flight, departing Wed, Sep 24 from Buffalo to Myrtle Beach, returning Tue, Sep 30, priced at $217 just found
Southwest Airlines
Tue, Aug 5 - Tue, Aug 12
BUF
Buffalo
MYR
Myrtle Beach
$218 Roundtrip, found 19 hours ago
$218
Roundtrip
found 19 hours ago
Select Southwest Airlines flight, departing Tue, Aug 5 from Buffalo to Myrtle Beach, returning Tue, Aug 12, priced at $218 found 19 hours ago
United
Sun, Aug 31 - Wed, Sep 3
BUF
Buffalo
MYR
Myrtle Beach
$230 Roundtrip, found 2 days ago
$230
Roundtrip
found 2 days ago
Select United flight, departing Sun, Aug 31 from Buffalo to Myrtle Beach, returning Wed, Sep 3, priced at $230 found 2 days ago

Find the cheapest month to fly from Buffalo (BUF) to Myrtle Beach (MYR)

September is typically the cheapest month to fly

From $191 - $355 per traveler.

Graph displaying average flight prices per month

Alternative airports near Myrtle Beach

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Myrtle Beach Intl. Airport MYR. Cheapest and Closest option available. Average driving time to city center is 6 minutes. Flights from $257
MYR
Myrtle Beach Intl. Airport
CheapestClosest
Average driving time to city center6 min
Flights from $257
Flights from Buffalo (BUF) to Myrtle Beach (MYR)
Origin airport
Buffalo Niagara Intl.
Destination airport
Myrtle Beach Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$203
Distance
639 mi

Buffalo to Myrtle Beach Flights

The cheapest times to fly from Buffalo to Myrtle Beach

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buffalo to Myrtle Beach are during the month of October. You can find some of the cheapest flights from Buffalo to Myrtle Beach with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Buffalo to Myrtle Beach

Sunday is one of the best days to book for cheap flights from Buffalo to Myrtle Beach: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Buffalo to Myrtle Beach

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buffalo to Myrtle Beach in 2025. You can also book with separate airlines for your outbound and return journeys, from $100 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buffalo to Myrtle Beach flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Buffalo to Myrtle Beach airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR) cost?
Discover the latest flight deals from BUF to MYR by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from BUF to MYR?
The cheapest flights from BUF to MYR are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from BUF to MYR?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from BUF to MYR. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR)?
Nonstop flights from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR) aren't available daily, so you'll have to take a flight with a layover. Explore your options with our filter tool. Enter your travel dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from BUF to MYR?
Generally you'll find the widest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* But this can vary depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR)?
Choose a flight from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR) that takes off before 3 PM to reduce the likelihood of delays and cancellations. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR) last-minute?
Waiting until just before your trip to book a ticket from BUF to MYR generally means paying more. While it's possible to find some last-minute deals, they're not always guaranteed. Allow some flexibility in your schedule for the best chance of landing a bargain.
Is it cheaper to book a BUF to MYR flight and hotel package?
You'll generally save money by securing a BUF to MYR flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one convenient place. After selecting your preferred accommodations and flights, consider other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR)?
If you booked your BUF to MYR flight within the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

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*Available to One Key members.