$399 Cheap Flights from Des Moines (DSM) to Champaign (CMI)

View $399 flight on Mon, Sep 29, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Champaign, IL (CMI-University Of Illinois Urbana-Champaign Williard)

    notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
    deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
    trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Des Moines to Champaign (DSM-CMI)

Prices were available within the past 7 days and start at $399 for one-way flights and $470 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Oct 8 - Thu, Oct 16
DSM
Des Moines
CMI
Champaign
$470 Roundtrip, found 6 days ago
$470
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Oct 8 from Des Moines to Champaign, returning Thu, Oct 16, priced at $470 found 6 days ago
American Airlines
Wed, Sep 24 - Tue, Sep 30
DSM
Des Moines
CMI
Champaign
$472 Roundtrip, found 18 hours ago
$472
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Wed, Sep 24 from Des Moines to Champaign, returning Tue, Sep 30, priced at $472 found 18 hours ago
American Airlines
Wed, Sep 24 - Sun, Sep 28
DSM
Des Moines
CMI
Champaign
$496 Roundtrip, found 18 hours ago
$496
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Wed, Sep 24 from Des Moines to Champaign, returning Sun, Sep 28, priced at $496 found 18 hours ago
American Airlines
Wed, Oct 8 - Sun, Oct 12
DSM
Des Moines
CMI
Champaign
$516 Roundtrip, found 6 days ago
$516
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Oct 8 from Des Moines to Champaign, returning Sun, Oct 12, priced at $516 found 6 days ago
American Airlines
Wed, Sep 24 - Sat, Sep 27
DSM
Des Moines
CMI
Champaign
$518 Roundtrip, found 18 hours ago
$518
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Wed, Sep 24 from Des Moines to Champaign, returning Sat, Sep 27, priced at $518 found 18 hours ago
American Airlines
Fri, Oct 10 - Sun, Oct 12
DSM
Des Moines
CMI
Champaign
$560 Roundtrip, found 6 days ago
$560
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Oct 10 from Des Moines to Champaign, returning Sun, Oct 12, priced at $560 found 6 days ago
American Airlines
Sun, Sep 28 - Sun, Oct 5
DSM
Des Moines
CMI
Champaign
$570 Roundtrip, found 6 days ago
$570
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sun, Sep 28 from Des Moines to Champaign, returning Sun, Oct 5, priced at $570 found 6 days ago
American Airlines
Sun, Sep 28 - Sun, Oct 5
DSM
Des Moines
CMI
Champaign
$615 Roundtrip, found 6 days ago
$615
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sun, Sep 28 from Des Moines to Champaign, returning Sun, Oct 5, priced at $615 found 6 days ago
American Airlines
Tue, Sep 23 - Wed, Sep 24
DSM
Des Moines
CMI
Champaign
$704 Roundtrip, found 18 hours ago
$704
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Tue, Sep 23 from Des Moines to Champaign, returning Wed, Sep 24, priced at $704 found 18 hours ago
American Airlines
Tue, Sep 23 - Fri, Sep 26
DSM
Des Moines
CMI
Champaign
$730 Roundtrip, found 18 hours ago
$730
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Tue, Sep 23 from Des Moines to Champaign, returning Fri, Sep 26, priced at $730 found 18 hours ago
American Airlines
Tue, Sep 23 - Thu, Sep 25
DSM
Des Moines
CMI
Champaign
$751 Roundtrip, found 18 hours ago
$751
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Tue, Sep 23 from Des Moines to Champaign, returning Thu, Sep 25, priced at $751 found 18 hours ago

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to University Of Illinois Urbana-Champaign Williard Airport (CMI) cost?
Grab a cheap one-way flight from $399 or cheap return flight from $470 from Des Moines Intl. Airport (DSM) to University Of Illinois Urbana-Champaign Williard Airport (CMI) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to University Of Illinois Urbana-Champaign Williard Airport (CMI)?
The cheapest month to fly from DSM to CMI is October, when demand is low. Off-peak season is usually when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to University Of Illinois Urbana-Champaign Williard Airport (CMI)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest DSM to CMI flight.
How many flights per day from Des Moines Intl. Airport (DSM) to University Of Illinois Urbana-Champaign Williard Airport (CMI)?
There are no daily direct flights available from Des Moines Intl. Airport (DSM) to University Of Illinois Urbana-Champaign Williard Airport (CMI). But you can choose flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be cruising above the clouds in no time.
What day of the week has the most flights from DSM to CMI?
Generally you'll have the most choice when it comes to flights on a Friday. Tuesdays are often the quietest.* But this can change based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to University Of Illinois Urbana-Champaign Williard Airport (CMI)?
Select a flight from Des Moines Intl. Airport (DSM) to University Of Illinois Urbana-Champaign Williard Airport (CMI) that leaves before 3 PM to reduce the likelihood of delays. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to University Of Illinois Urbana-Champaign Williard Airport (CMI) last-minute?
Last-minute fares from DSM to CMI are generally more expensive. To secure the best rates, start searching for flights as early as possible. That said, if you can play around with your travel dates, it's possible to score a cheap fare right before your trip.
Is it cheaper to book a DSM to CMI flight and hotel package?
You'll generally save money by securing a DSM to CMI flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. After choosing your ideal accommodations and flights, consider other add-ons like activities, car rentals and tours.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to University Of Illinois Urbana-Champaign Williard Airport (CMI)?
In most instances, you can cancel or modify your DSM to CMI flight. However, there may be additional fees, especially if you booked more than 24 hours ago. Check your itinerary for the airline's rules and fees on flight changes, or if you want more details, visit our Customer Service portal.

Travel information

Travel information

Origin airport
Des Moines Intl.
Destination airport
University Of Illinois Urbana-Champaign Williard
Airlines serving
American Airlines
Roundtrip price
$470
Distance
299 mi

Book with confidence

Book with confidence

Des Moines to Champaign Flights

The cheapest times to fly from Des Moines to Champaign

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Champaign are during the month of October. You can find some of the cheapest flights from Des Moines to Champaign with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Champaign

Sunday is one of the best days to book for cheap flights from Des Moines to Champaign: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Champaign

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Champaign in 2025. You can also book with separate airlines for your outbound and return journeys, from $399 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Champaign flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Champaign airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to Champaign Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.