$143 Cheap Flights from Indianapolis (IND) to San Francisco (SFO)

View $143 flight on Fri, Sep 5, 2025Opens in a new window

Popular airlines from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO)

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Cheap Flights from Indianapolis to San Francisco (IND-SFO)

Prices were available within the past 7 days and start at $143 for one-way flights and $180 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Tue, Oct 7 - Tue, Oct 28
IND
Indianapolis
SFO
San Francisco
$180 Roundtrip, found 2 days ago
$180
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Tue, Oct 7 from Indianapolis to San Francisco, returning Tue, Oct 28, priced at $180 found 2 days ago
Southwest Airlines
Thu, Nov 13 - Mon, Nov 17
IND
Indianapolis
SFO
San Francisco
$191 Roundtrip, found 1 day ago
$191
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Thu, Nov 13 from Indianapolis to San Francisco, returning Mon, Nov 17, priced at $191 found 1 day ago
Southwest Airlines
Tue, Oct 7 - Tue, Oct 28
IND
Indianapolis
SFO
San Francisco
$200 Roundtrip, found 2 days ago
$200
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Tue, Oct 7 from Indianapolis to San Francisco, returning Tue, Oct 28, priced at $200 found 2 days ago
Hawaiian Airlines
Wed, Aug 20 - Wed, Sep 3
IND
Indianapolis
SFO
San Francisco
$203 Roundtrip, found 2 days ago
$203
Roundtrip
found 2 days ago
Select Hawaiian Airlines flight, departing Wed, Aug 20 from Indianapolis to San Francisco, returning Wed, Sep 3, priced at $203 found 2 days ago
Southwest Airlines
Thu, Nov 20 - Mon, Nov 24
IND
Indianapolis
SFO
San Francisco
$208 Roundtrip, found 2 days ago
$208
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Thu, Nov 20 from Indianapolis to San Francisco, returning Mon, Nov 24, priced at $208 found 2 days ago
American Airlines
Thu, Nov 13 - Sun, Nov 16
IND
Indianapolis
SFO
San Francisco
$216 Roundtrip, found 1 day ago
$216
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Nov 13 from Indianapolis to San Francisco, returning Sun, Nov 16, priced at $216 found 1 day ago
United
Fri, Sep 5 - Mon, Sep 8
IND
Indianapolis
SFO
San Francisco
$269 Roundtrip, just found
$269
Roundtrip
just found
Select United flight, departing Fri, Sep 5 from Indianapolis to San Francisco, returning Mon, Sep 8, priced at $269 just found
Frontier Airlines
Fri, Sep 19 - Wed, Sep 24
IND
Indianapolis
SFO
San Francisco
$271 Roundtrip, just found
$271
Roundtrip
just found
Select Frontier Airlines flight, departing Fri, Sep 19 from Indianapolis to San Francisco, returning Wed, Sep 24, priced at $271 just found
Frontier Airlines
Fri, Aug 29 - Wed, Sep 3
IND
Indianapolis
SFO
San Francisco
$272 Roundtrip, just found
$272
Roundtrip
just found
Select Frontier Airlines flight, departing Fri, Aug 29 from Indianapolis to San Francisco, returning Wed, Sep 3, priced at $272 just found
Alaska Airlines
Thu, Sep 4 - Tue, Sep 9
IND
Indianapolis
SFO
San Francisco
$274 Roundtrip, just found
$274
Roundtrip
just found
Select Alaska Airlines flight, departing Thu, Sep 4 from Indianapolis to San Francisco, returning Tue, Sep 9, priced at $274 just found

Find the cheapest month to fly from Indianapolis (IND) to San Francisco (SFO)

September is typically the cheapest month to fly

From $158 - $243 per traveler.

Graph displaying average flight prices per month

Flights from Indianapolis (IND) to San Francisco (SFO)
Origin airport
Indianapolis Intl.
Destination airport
San Francisco Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Frontier Airlines, Hawaiian Airlines, Southwest Airlines, Sun Country Airlines, United
Roundtrip price
$180
Distance
1939 mi
Average flight time
2 hours 51 mins

Indianapolis to San Francisco Flights

The cheapest times to fly from Indianapolis to San Francisco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Indianapolis to San Francisco are during the month of October. You can find some of the cheapest flights from Indianapolis to San Francisco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Indianapolis to San Francisco

Sunday is one of the best days to book for cheap flights from Indianapolis to San Francisco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Indianapolis to San Francisco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Indianapolis to San Francisco in 2025. You can also book with separate airlines for your outbound and return journeys, from $143 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Indianapolis to San Francisco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Indianapolis to San Francisco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO) cost?
You can land affordable return tickets from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO) starting from $269. Reserve your seat and get ready to go. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a United flight leaving IND on August 7 2025 and touching down at SFO. The price was last updated on July 11 2025 and has not changed since.
What is the cheapest month to fly from IND to SFO?
The cheapest flights from IND to SFO are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO)?
Board a nonstop flight with United Airlines and go straight from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO).
What is the cheapest airline that flies from IND to SFO?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from IND to SFO. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO)?
On average, there's only 1 nonstop flight operating from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO) every day. If this doesn't fit your travel plans, consider flights with layovers. Simply filter your search on Expedia to include one stop or more to discover a better alternative.
What are the most popular departure times for flights from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO)?
Flights between IND and SFO are busiest at 7 AM. If you're after a more relaxed experience and potentially cheaper fares, choose a departure outside the usual busy windows.
What day of the week has the most flights from IND to SFO?
Jet off on a Friday if you're searching for the best choice of flights from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO).
What is the earliest flight from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO)?
The first flight of the day departing from Indianapolis Intl. Airport (IND) is at around 7:33AM UTC-5. Board this plane and you'll land at San Francisco Intl. Airport (SFO) at approximately 9:38AM UTC-8. The overall travel time is 5h 5m.
How long does it take to fly from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO)?
The average flight duration from IND to SFO is 5 hours and 5 minutes, covering a distance of 1,950 mi.
What airline has the least delays from IND to SFO?
United Airlines has the best performance for on-time direct flights from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO), with an on-time rating of 82%. Use the Expedia App to view your flight status before you go and get real-time updates about any trip changes.
What is the best time to fly from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO)?
To reach San Francisco Intl. Airport (SFO) on time, opt for a flight that leaves from Indianapolis Intl. Airport (IND) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for San Francisco from Indianapolis Intl. Airport (IND)?
San Francisco Intl. Airport (SFO) is the only airport in San Francisco with direct flights from Indianapolis Intl. Airport (IND). Browse the available options and find affordable fares on Expedia.
Is it cheaper to buy a plane ticket from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO) last-minute?
Booking your ticket from IND to SFO shortly before your journey is typically more expensive. However, if there's some wiggle room with your travel dates and times, you could score a cheap last-minute fare.
Is it cheaper to book an IND to SFO flight and hotel package?
You'll generally save money by securing an IND to SFO flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. Once you've selected your preferred flights and accommodations, consider adding extras like car rentals, activities and tours.
Can I cancel or change the date of my flight from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO)?
Generally, it's possible to cancel or reschedule your IND to SFO flight. However, if it's been more than 24 hours since booking, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.