$291 Cheap Flights from Lexington (LEX) to Florence (FLO)

View $291 flight on Mon, Jul 13, 2026Opens in a new window

Popular airlines from Blue Grass Airport (LEX) to Florence, SC (FLO-Florence Regional)

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Cheap Flights from Lexington to Florence (LEX-FLO)

Prices were available within the past 7 days and start at $291 for one-way flights and $541 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Apr 7 - Tue, Apr 14
LEX
Lexington
FLO
Florence
$541 Roundtrip, found 3 hours ago
$541
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Tue, Apr 7 from Lexington to Florence, returning Tue, Apr 14, priced at $541 found 3 hours ago
American Airlines
Tue, Apr 7 - Tue, Apr 14
LEX
Lexington
FLO
Florence
$570 Roundtrip, found 1 day ago
$570
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Apr 7 from Lexington to Florence, returning Tue, Apr 14, priced at $570 found 1 day ago
American Airlines
Tue, Apr 7 - Tue, Apr 14
LEX
Lexington
FLO
Florence
$590 Roundtrip, found 3 hours ago
$590
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Tue, Apr 7 from Lexington to Florence, returning Tue, Apr 14, priced at $590 found 3 hours ago
American Airlines
Tue, Apr 7 - Tue, Apr 14
LEX
Lexington
FLO
Florence
$641 Roundtrip, found 3 hours ago
$641
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Tue, Apr 7 from Lexington to Florence, returning Tue, Apr 14, priced at $641 found 3 hours ago
American Airlines
Tue, Apr 7 - Tue, Apr 14
LEX
Lexington
FLO
Florence
$663 Roundtrip, found 3 hours ago
$663
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Tue, Apr 7 from Lexington to Florence, returning Tue, Apr 14, priced at $663 found 3 hours ago
American Airlines
Tue, Apr 7 - Tue, Apr 14
LEX
Lexington
FLO
Florence
$670 Roundtrip, found 1 day ago
$670
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Apr 7 from Lexington to Florence, returning Tue, Apr 14, priced at $670 found 1 day ago
American Airlines
Tue, Apr 7 - Tue, Apr 14
LEX
Lexington
FLO
Florence
$681 Roundtrip, found 3 hours ago
$681
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Tue, Apr 7 from Lexington to Florence, returning Tue, Apr 14, priced at $681 found 3 hours ago
American Airlines
Tue, Apr 7 - Tue, Apr 14
LEX
Lexington
FLO
Florence
$690 Roundtrip, found 3 hours ago
$690
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Tue, Apr 7 from Lexington to Florence, returning Tue, Apr 14, priced at $690 found 3 hours ago
American Airlines
Tue, Apr 7 - Tue, Apr 14
LEX
Lexington
FLO
Florence
$692 Roundtrip, found 1 day ago
$692
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Apr 7 from Lexington to Florence, returning Tue, Apr 14, priced at $692 found 1 day ago
American Airlines
Tue, Apr 7 - Tue, Apr 14
LEX
Lexington
FLO
Florence
$712 Roundtrip, found 3 hours ago
$712
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Tue, Apr 7 from Lexington to Florence, returning Tue, Apr 14, priced at $712 found 3 hours ago
American Airlines
Tue, Apr 7 - Tue, Apr 14
LEX
Lexington
FLO
Florence
$739 Roundtrip, found 1 day ago
$739
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Apr 7 from Lexington to Florence, returning Tue, Apr 14, priced at $739 found 1 day ago
American Airlines
Tue, Apr 7 - Tue, Apr 14
LEX
Lexington
FLO
Florence
$779 Roundtrip, found 3 hours ago
$779
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Tue, Apr 7 from Lexington to Florence, returning Tue, Apr 14, priced at $779 found 3 hours ago
American Airlines
Tue, Apr 7 - Tue, Apr 14
LEX
Lexington
FLO
Florence
$917 Roundtrip, found 3 hours ago
$917
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Tue, Apr 7 from Lexington to Florence, returning Tue, Apr 14, priced at $917 found 3 hours ago

Frequently asked questions

How much does a flight from Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional) cost?
You can find cheap one-way flights from $291 and cheap return flights from $541 Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional) with Expedia. One-way flights generally range between $393 and $498. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional)?
The cheapest month to fly from LEX to FLO is April when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional)?
Enter LEX to FLO and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional)?
American Airlines is just one of the carriers that fly from Lexington, KY (LEX) to Florence, SC (FLO). Use Expedia's flight search tool to compare airlines on this route and find our cheapest option for your trip. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional)?
To find a cheap flight from Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional)?
Sort flights by "Departure (earliest)" on Expedia to find the earliest flight from LEX to FLO. To compare more early flights, use the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional)?
The busiest day for flights from Blue Grass (LEX) to Florence Regional (FLO) is a Tuesday, with around 3 flights. This gives you plenty of options for your travel plans. A major airline on this route is American Airlines.
What are the most popular departure times for flights from Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional)?
The most popular departure times for flights from Blue Grass (LEX) to Florence Regional (FLO) are in the late morning, from 9am to noon. About 48% of passengers prefer this time window. American Airlines offers flights during this window. This timing is convenient for travelers looking to arrive in Florence with ample time to explore.
How long does it take to fly from Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional)?
Flying from LEX to FLO with a connection usually takes about 4 hours, traveling roughly 380 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional)?
Select the "Business class" and "First class" filters when looking for LEX to FLO flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional) flight with Expedia?
It's easy to earn miles on a Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Florence from Blue Grass (LEX)?
When traveling from Blue Grass (LEX) to Florence, you can fly into Florence Regional (FLO) and Peretola (FLR). Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional) at the last minute?
Typically, booking a last minute flight from Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional) flight and hotel package?
Securing a Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional)?
If you booked your Lexington, KY (LEX-Blue Grass) to Florence, SC (FLO-Florence Regional) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Blue Grass
Destination airport
Florence Regional
Airlines serving
American Airlines
Roundtrip price
$540
Distance
379 mi

Book with confidence

Lexington to Florence Flights

The cheapest times to fly from Lexington to Florence

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Lexington to Florence are during the month of April. You can find some of the cheapest flights from Lexington to Florence with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Lexington to Florence

Sunday is one of the best days to book for cheap flights from Lexington to Florence: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Lexington to Florence

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Lexington to Florence in 2026. You can also book with separate airlines for your outbound and return journeys, from $291 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Lexington to Florence flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Lexington to Florence airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Lexington to Florence Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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