$79 Cheap Flights from Muscle Shoals (MSL) to Charlotte (CLT)

View $79 flight on Mon, Jan 19, 2026Opens in a new window

Popular airlines from Muscle Shoals, AL (MSL-Northwest Alabama Regional) to Charlotte-Douglas Intl. Airport (CLT)

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Cheap Flights from Muscle Shoals to Charlotte (MSL-CLT)

Prices were available within the past 7 days and start at $79 for one-way flights and $158 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Contour Airlines
Fri, Mar 20 - Mon, Mar 23
MSL
Muscle Shoals
CLT
Charlotte
$158 Roundtrip, found 2 hours ago
$158
Roundtrip
found 2 hours ago
Select Contour Airlines flight, departing Fri, Mar 20 from Muscle Shoals to Charlotte, returning Mon, Mar 23, priced at $158 found 2 hours ago
Contour Airlines
Sun, Nov 23 - Mon, Dec 1
MSL
Muscle Shoals
CLT
Charlotte
$168 Roundtrip, found 7 hours ago
$168
Roundtrip
found 7 hours ago
Select Contour Airlines flight, departing Sun, Nov 23 from Muscle Shoals to Charlotte, returning Mon, Dec 1, priced at $168 found 7 hours ago
Contour Airlines
Wed, Nov 19 - Sun, Nov 23
MSL
Muscle Shoals
CLT
Charlotte
$178 Roundtrip, found 5 hours ago
$178
Roundtrip
found 5 hours ago
Select Contour Airlines flight, departing Wed, Nov 19 from Muscle Shoals to Charlotte, returning Sun, Nov 23, priced at $178 found 5 hours ago
Contour Airlines
Sat, Nov 29 - Sun, Dec 14
MSL
Muscle Shoals
CLT
Charlotte
$188 Roundtrip, found 7 hours ago
$188
Roundtrip
found 7 hours ago
Select Contour Airlines flight, departing Sat, Nov 29 from Muscle Shoals to Charlotte, returning Sun, Dec 14, priced at $188 found 7 hours ago
Contour Airlines
Sun, Nov 16 - Thu, Nov 20
MSL
Muscle Shoals
CLT
Charlotte
$198 Roundtrip, found 5 hours ago
$198
Roundtrip
found 5 hours ago
Select Contour Airlines flight, departing Sun, Nov 16 from Muscle Shoals to Charlotte, returning Thu, Nov 20, priced at $198 found 5 hours ago
Contour Airlines
Wed, Nov 26 - Sat, Nov 29
MSL
Muscle Shoals
CLT
Charlotte
$208 Roundtrip, found 7 hours ago
$208
Roundtrip
found 7 hours ago
Select Contour Airlines flight, departing Wed, Nov 26 from Muscle Shoals to Charlotte, returning Sat, Nov 29, priced at $208 found 7 hours ago
Contour Airlines
Wed, Nov 19 - Tue, Nov 25
MSL
Muscle Shoals
CLT
Charlotte
$218 Roundtrip, found 5 hours ago
$218
Roundtrip
found 5 hours ago
Select Contour Airlines flight, departing Wed, Nov 19 from Muscle Shoals to Charlotte, returning Tue, Nov 25, priced at $218 found 5 hours ago
Contour Airlines
Sun, Nov 30 - Sun, Dec 14
MSL
Muscle Shoals
CLT
Charlotte
$228 Roundtrip, found 7 hours ago
$228
Roundtrip
found 7 hours ago
Select Contour Airlines flight, departing Sun, Nov 30 from Muscle Shoals to Charlotte, returning Sun, Dec 14, priced at $228 found 7 hours ago
Contour Airlines
Sun, Nov 16 - Tue, Nov 25
MSL
Muscle Shoals
CLT
Charlotte
$238 Roundtrip, found 5 hours ago
$238
Roundtrip
found 5 hours ago
Select Contour Airlines flight, departing Sun, Nov 16 from Muscle Shoals to Charlotte, returning Tue, Nov 25, priced at $238 found 5 hours ago
Contour Airlines
Fri, Nov 28 - Sun, Dec 14
MSL
Muscle Shoals
CLT
Charlotte
$248 Roundtrip, found 7 hours ago
$248
Roundtrip
found 7 hours ago
Select Contour Airlines flight, departing Fri, Nov 28 from Muscle Shoals to Charlotte, returning Sun, Dec 14, priced at $248 found 7 hours ago
Contour Airlines
Sun, Nov 23 - Sun, Nov 30
MSL
Muscle Shoals
CLT
Charlotte
$258 Roundtrip, found 7 hours ago
$258
Roundtrip
found 7 hours ago
Select Contour Airlines flight, departing Sun, Nov 23 from Muscle Shoals to Charlotte, returning Sun, Nov 30, priced at $258 found 7 hours ago

Find the cheapest month to fly from Muscle Shoals (MSL) to Charlotte (CLT)

December is typically the cheapest month to fly

From $118 - $188 per traveler.

Alternative airports near Charlotte

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Charlotte-Douglas Intl. CLT. Cheapest and Closest option available. Average driving time to city center is 11 minutes. Flights from $158
CLT
Charlotte-Douglas Intl.
CheapestClosest
Average driving time to city center11 min
Flights from $158

Frequently asked questions

How much does a flight from Northwest Alabama Regional Airport (MSL) to Charlotte-Douglas Intl. Airport (CLT) cost?
Grab a cheap one-way flight from $79 or cheap return flight from $158 from Northwest Alabama Regional Airport (MSL) to Charlotte-Douglas Intl. Airport (CLT) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Northwest Alabama Regional Airport (MSL) to Charlotte-Douglas Intl. Airport (CLT)?
March is the least expensive month to fly from MSL to CLT. Traveling during an off-peak travel window is often the key to scoring lower fares.
Which airlines fly direct from Northwest Alabama Regional Airport (MSL) to Charlotte-Douglas Intl. Airport (CLT)?
When departing from Northwest Alabama Regional Airport (MSL), you can jump on a direct flight to Charlotte-Douglas Intl. Airport (CLT) with Contour Aviation.
What is the cheapest airline that flies from Northwest Alabama Regional Airport (MSL) to Charlotte-Douglas Intl. Airport (CLT)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest MSL to CLT flight.
How many flights per day from Northwest Alabama Regional Airport (MSL) to Charlotte-Douglas Intl. Airport (CLT)?
On average, Northwest Alabama Regional Airport (MSL) only offers 1 direct flight to Charlotte-Douglas Intl. Airport (CLT) daily. For additional options, try our easy-to-use filters. Simply enter your details, then click on "1 Stop" or "2+ Stops" to discover flights offering layovers.
What are the most popular departure times for flights from Northwest Alabama Regional Airport (MSL) to Charlotte-Douglas Intl. Airport (CLT)?
The 7 AM departures from MSL to CLT are typically the busiest. Prices can be higher for these popular slots. If you want to save on your fare, pick a less crowded time to fly.
What day of the week has the most flights from MSL to CLT?
Fly on a Friday if you're searching for the biggest selection of flights from Northwest Alabama Regional Airport (MSL) to Charlotte-Douglas Intl. Airport (CLT).
What is the earliest flight from Northwest Alabama Regional Airport (MSL) to Charlotte-Douglas Intl. Airport (CLT)?
The earliest flight leaving from Northwest Alabama Regional Airport (MSL) is at around 7:25AM UTC-6. Hop on this flight and you'll land at Charlotte-Douglas Intl. Airport (CLT) at approximately 10:00AM UTC-5. The total travel time is 1h 35m.
How long does it take to fly from Northwest Alabama Regional Airport (MSL) to Charlotte-Douglas Intl. Airport (CLT)?
Typically, it takes 1 hour and 35 minutes to travel the 380 mi from MSL to CLT.
What is the best time to fly from Northwest Alabama Regional Airport (MSL) to Charlotte-Douglas Intl. Airport (CLT)?
To touch down at Charlotte-Douglas Intl. Airport (CLT) without delays, opt for a flight that takes off from Northwest Alabama Regional Airport (MSL) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Charlotte from Northwest Alabama Regional Airport (MSL)?
If you've booked a direct flight from Northwest Alabama Regional Airport (MSL) to Charlotte, Charlotte-Douglas Intl. Airport (CLT) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Northwest Alabama Regional Airport (MSL) to Charlotte-Douglas Intl. Airport (CLT) last-minute?
Waiting until just before your departure to book your flight from MSL to CLT often results in higher prices. While you may find some last-minute deals, they aren't always guaranteed. Keep your travel plans flexible to boost your chances of snagging a bargain.
Is it cheaper to book a MSL to CLT flight and hotel package?
You'll generally save money by booking a MSL to CLT flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. Once you've chosen your ideal accommodations and flights, consider adding extras including tours, activities and car rentals.
Can I cancel or change the date of my flight from Northwest Alabama Regional Airport (MSL) to Charlotte-Douglas Intl. Airport (CLT)?
In most cases, you can modify or cancel your MSL to CLT flight. However, additional charges may apply, especially if you booked over 24 hours ago. Double-check your itinerary for the airline's fees and guidelines on flight changes, or if you'd like more information, head to our Customer Service portal.

Travel information

Origin airport
Northwest Alabama Regional
Destination airport
Charlotte-Douglas Intl.
Airlines serving
Contour Airlines
Roundtrip price
$152
Distance
379 mi
Average flight time
2 hours 35 mins

Book with confidence

Muscle Shoals to Charlotte Flights

The cheapest times to fly from Muscle Shoals to Charlotte

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Muscle Shoals to Charlotte are during the month of March. You can find some of the cheapest flights from Muscle Shoals to Charlotte with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Muscle Shoals to Charlotte

Sunday is one of the best days to book for cheap flights from Muscle Shoals to Charlotte: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Muscle Shoals to Charlotte

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Muscle Shoals to Charlotte in 2025. You can also book with separate airlines for your outbound and return journeys, from $79 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Muscle Shoals to Charlotte flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Muscle Shoals to Charlotte airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Muscle Shoals to Charlotte Flights

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*Available to One Key members.