Cheap Flights from Minneapolis (MSP) to Florence (FLO)

Popular airlines from Minneapolis - St. Paul Intl. Airport (MSP) to Florence, SC (FLO-Florence Regional)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • one key icon

    Earn twice

    Earn your airline miles on top of our OneKeyCash

Cheap Flights from Minneapolis to Florence (MSP-FLO)

Prices were available within the past 7 days and start at for one-way flights and $441 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines

Frequently asked questions

How much does a flight from Minneapolis - St. Paul Intl. Airport (MSP) to Florence Regional Airport (FLO) cost?
Lock in a cheap one-way flight or cheap return flight from $441 from Minneapolis - St. Paul Intl. Airport (MSP) to Florence Regional Airport (FLO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Minneapolis - St. Paul Intl. Airport (MSP) to Florence Regional Airport (FLO)?
The cheapest month to fly from MSP to FLO is October, when there's less demand. Off-peak season is typically when you'll find lower airfares between these airports.
What is the cheapest airline that flies from Minneapolis - St. Paul Intl. Airport (MSP) to Florence Regional Airport (FLO)?
To find the cheapest airline that'll fly you from MSP to FLO, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Minneapolis - St. Paul Intl. Airport (MSP) to Florence Regional Airport (FLO)?
There are no daily direct flights departing from Minneapolis - St. Paul Intl. Airport (MSP) to Florence Regional Airport (FLO). But you can choose flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be on your way in no time.
What day of the week has the most flights from MSP to FLO?
You'll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Minneapolis - St. Paul Intl. Airport (MSP) to Florence Regional Airport (FLO)?
To avoid possible delays on the Minneapolis - St. Paul Intl. Airport (MSP) to Florence Regional Airport (FLO) route, aim to travel before 3 PM. Departures after this hour are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Minneapolis - St. Paul Intl. Airport (MSP) to Florence Regional Airport (FLO) last-minute?
Waiting until just before your departure to book a ticket from MSP to FLO often results in higher prices. While it's possible to find some last-minute deals, they're not always guaranteed. Keep your travel schedule open for a better chance of landing a bargain.
Is it cheaper to book a MSP to FLO flight and hotel package?
Compared with arranging flights and hotels separately, booking a MSP to FLO flight and hotel package with Expedia could lead to significant savings. What's more, having it all in one place will take the hassle out of planning your trip. Simply secure your flights and select from our wide range of stays, then personalize your trip with other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Minneapolis - St. Paul Intl. Airport (MSP) to Florence Regional Airport (FLO)?
Typically, you can modify or cancel your MSP to FLO flight. However, there may be additional charges, especially if you booked over 24 hours ago. Check your itinerary for the airline's fees and guidelines on flight changes, or if you'd like more details, visit our Customer Service portal.

Travel information

Travel information

Origin airport
Minneapolis - St. Paul Intl.
Destination airport
Florence Regional
Airlines serving
American Airlines
Roundtrip price
$440
Distance
1027 mi

Book with confidence

Book with confidence

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.