$303 Cheap Flights from Phoenix (PHX) to Florence (FLO)

View $303 flight on Fri, Oct 31, 2025Opens in a new window

Popular airlines from Phoenix Sky Harbor Intl. Airport (PHX) to Florence, SC (FLO-Florence Regional)

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Cheap Flights from Phoenix to Florence (PHX-FLO)

Prices were available within the past 7 days and start at $303 for one-way flights and $441 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Mon, May 11 - Wed, Jun 3
PHX
Phoenix
FLO
Florence
$441 Roundtrip, found 5 days ago
$441
Roundtrip
found 5 days ago
Select American Airlines flight, departing Mon, May 11 from Phoenix to Florence, returning Wed, Jun 3, priced at $441 found 5 days ago
American Airlines
Thu, Jan 1 - Tue, Jan 6
PHX
Phoenix
FLO
Florence
$467 Roundtrip, found 4 days ago
$467
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Jan 1 from Phoenix to Florence, returning Tue, Jan 6, priced at $467 found 4 days ago
American Airlines
Thu, Jan 1 - Tue, Jan 6
PHX
Phoenix
FLO
Florence
$476 Roundtrip, found 4 days ago
$476
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Jan 1 from Phoenix to Florence, returning Tue, Jan 6, priced at $476 found 4 days ago
American Airlines
Fri, Nov 21 - Fri, Nov 28
PHX
Phoenix
FLO
Florence
$479 Roundtrip, found 2 days ago
$479
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Nov 21 from Phoenix to Florence, returning Fri, Nov 28, priced at $479 found 2 days ago
American Airlines
Thu, Jan 1 - Tue, Jan 6
PHX
Phoenix
FLO
Florence
$480 Roundtrip, found 4 days ago
$480
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Jan 1 from Phoenix to Florence, returning Tue, Jan 6, priced at $480 found 4 days ago
American Airlines
Wed, Dec 31 - Sat, Jan 17
PHX
Phoenix
FLO
Florence
$493 Roundtrip, found 2 days ago
$493
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Dec 31 from Phoenix to Florence, returning Sat, Jan 17, priced at $493 found 2 days ago
American Airlines
Thu, Jan 1 - Tue, Jan 6
PHX
Phoenix
FLO
Florence
$496 Roundtrip, found 4 days ago
$496
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Jan 1 from Phoenix to Florence, returning Tue, Jan 6, priced at $496 found 4 days ago
American Airlines
Tue, Dec 30 - Sat, Jan 10
PHX
Phoenix
FLO
Florence
$498 Roundtrip, found 2 days ago
$498
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Dec 30 from Phoenix to Florence, returning Sat, Jan 10, priced at $498 found 2 days ago
American Airlines
Fri, Nov 21 - Fri, Nov 28
PHX
Phoenix
FLO
Florence
$500 Roundtrip, found 2 days ago
$500
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Nov 21 from Phoenix to Florence, returning Fri, Nov 28, priced at $500 found 2 days ago
American Airlines
Thu, Jan 1 - Tue, Jan 6
PHX
Phoenix
FLO
Florence
$502 Roundtrip, found 4 days ago
$502
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Jan 1 from Phoenix to Florence, returning Tue, Jan 6, priced at $502 found 4 days ago

Alternative airports near Florence

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Florence Regional FLO. Cheapest and Closest option available. Average driving time to city center is 5 minutes. Flights from $552
FLO
Florence Regional
CheapestClosest
Average driving time to city center5 min
Flights from $552
Flights from Phoenix (PHX) to Florence (FLO)
Origin airport
Sky Harbor Intl.
Destination airport
Florence Regional
Airlines serving
American Airlines
Roundtrip price
$440
Distance
1846 mi

Phoenix to Florence Flights

The cheapest times to fly from Phoenix to Florence

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Phoenix to Florence are during the month of May. You can find some of the cheapest flights from Phoenix to Florence with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Phoenix to Florence

Sunday is one of the best days to book for cheap flights from Phoenix to Florence: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Phoenix to Florence

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Phoenix to Florence in 2025. You can also book with separate airlines for your outbound and return journeys, from $303 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Phoenix to Florence flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Phoenix to Florence airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Sky Harbor Intl. Airport (PHX) to Florence Regional Airport (FLO) cost?
Grab a cheap one-way flight from $303 or cheap return flight from $441 from Sky Harbor Intl. Airport (PHX) to Florence Regional Airport (FLO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Sky Harbor Intl. Airport (PHX) to Florence Regional Airport (FLO)?
The cheapest month to fly from PHX to FLO is May, when demand is low. Off-peak months are usually when better flight deals are available between these airports.
What is the cheapest airline that flies from Sky Harbor Intl. Airport (PHX) to Florence Regional Airport (FLO)?
Use the filter tool on Expedia to compare different airlines and find the cheapest carrier that'll take you from PHX to FLO. Then, sort your results by "Price (lowest to highest)" to snag a great deal.
How many flights per day from Sky Harbor Intl. Airport (PHX) to Florence Regional Airport (FLO)?
You'll have to take a flight with a layover when traveling from Sky Harbor Intl. Airport (PHX) to Florence Regional Airport (FLO). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from PHX to FLO?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can change based on a range of factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Sky Harbor Intl. Airport (PHX) to Florence Regional Airport (FLO)?
To touch down at Florence Regional Airport (FLO) without delays, select a flight that leaves from Sky Harbor Intl. Airport (PHX) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Sky Harbor Intl. Airport (PHX) to Florence Regional Airport (FLO) last-minute?
Booking your ticket from PHX to FLO just before your getaway is usually more expensive. But if there's some wiggle room with your travel times and dates, you could land a cheap last-minute fare.
Is it cheaper to book a PHX to FLO flight and hotel package?
You can save money by securing a PHX to FLO flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. After selecting your ideal flights and accommodations, consider adding extras including tours, activities and car rentals.
Can I cancel or change the date of my flight from Sky Harbor Intl. Airport (PHX) to Florence Regional Airport (FLO)?
In most cases, you can reschedule or cancel your PHX to FLO flight. However, there may be additional charges, especially if your booking was made over 24 hours ago. Check your itinerary for the airline's fees and rules on flight changes, or if you need further information, head to our Customer Service portal.

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*Available to One Key members.