$512 Cheap Flights from Phoenix (PHX) to La Serena (LSC)

View $512 flight on Wed, Apr 1, 2026Opens in a new window

Popular airlines from Phoenix Sky Harbor Intl. Airport (PHX) to La Serena (LSC-La Florida)

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 30% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Phoenix to La Serena (PHX-LSC)

Prices were available within the past 7 days and start at $512 for one-way flights and $1,471 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Tue, Mar 17 - Tue, Mar 31
PHX
Phoenix
LSC
La Serena
$1,471 Roundtrip, found 2 days ago
$1,471
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, Mar 17 from Phoenix to La Serena, returning Tue, Mar 31, priced at $1,471 found 2 days ago
LATAM Airlines Group
Tue, Mar 17 - Tue, Mar 31
PHX
Phoenix
LSC
La Serena
$1,756 Roundtrip, found 2 days ago
$1,756
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, Mar 17 from Phoenix to La Serena, returning Tue, Mar 31, priced at $1,756 found 2 days ago
LATAM Airlines Group
Tue, Mar 17 - Tue, Mar 31
PHX
Phoenix
LSC
La Serena
$1,897 Roundtrip, found 2 days ago
$1,897
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, Mar 17 from Phoenix to La Serena, returning Tue, Mar 31, priced at $1,897 found 2 days ago
LATAM Airlines Group
Tue, Mar 17 - Tue, Mar 31
PHX
Phoenix
LSC
La Serena
$1,999 Roundtrip, found 2 days ago
$1,999
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, Mar 17 from Phoenix to La Serena, returning Tue, Mar 31, priced at $1,999 found 2 days ago
LATAM Airlines Group
Tue, Mar 17 - Tue, Mar 31
PHX
Phoenix
LSC
La Serena
$2,182 Roundtrip, found 2 days ago
$2,182
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, Mar 17 from Phoenix to La Serena, returning Tue, Mar 31, priced at $2,182 found 2 days ago
LATAM Airlines Group
Tue, Mar 17 - Tue, Mar 31
PHX
Phoenix
LSC
La Serena
$2,202 Roundtrip, found 2 days ago
$2,202
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, Mar 17 from Phoenix to La Serena, returning Tue, Mar 31, priced at $2,202 found 2 days ago
LATAM Airlines Group
Tue, Mar 17 - Tue, Mar 31
PHX
Phoenix
LSC
La Serena
$2,277 Roundtrip, found 2 days ago
$2,277
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, Mar 17 from Phoenix to La Serena, returning Tue, Mar 31, priced at $2,277 found 2 days ago
LATAM Airlines Group
Tue, Mar 17 - Tue, Mar 31
PHX
Phoenix
LSC
La Serena
$2,425 Roundtrip, found 2 days ago
$2,425
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, Mar 17 from Phoenix to La Serena, returning Tue, Mar 31, priced at $2,425 found 2 days ago
LATAM Airlines Group
Tue, Mar 17 - Tue, Mar 31
PHX
Phoenix
LSC
La Serena
$2,445 Roundtrip, found 2 days ago
$2,445
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, Mar 17 from Phoenix to La Serena, returning Tue, Mar 31, priced at $2,445 found 2 days ago
JetBlue Airways
Tue, Mar 17 - Tue, Mar 31
PHX
Phoenix
LSC
La Serena
$2,478 Roundtrip, found 2 days ago
$2,478
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Tue, Mar 17 from Phoenix to La Serena, returning Tue, Mar 31, priced at $2,478 found 2 days ago

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.
Book now

Frequently asked questions

How much does a flight from Sky Harbor Intl. Airport (PHX) to La Florida Airport (LSC) cost?
Lock in a cheap one-way flight from $512 or cheap return flight from $1,471 from Sky Harbor Intl. Airport (PHX) to La Florida Airport (LSC) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Sky Harbor Intl. Airport (PHX) to La Florida Airport (LSC)?
Planning your trip for March is a great way to save, as it's the cheapest month for flights between PHX and LSC. You'll usually find the lowest prices during off-peak months.
What is the cheapest airline that flies from Sky Harbor Intl. Airport (PHX) to La Florida Airport (LSC)?
Use the filters on Expedia to compare different airlines and find the cheapest carrier that'll take you from PHX to LSC. Then, sort your results by "Price (lowest to highest)" to pick up the best deal available.
How many flights per day from Sky Harbor Intl. Airport (PHX) to La Florida Airport (LSC)?
Direct flights from Sky Harbor Intl. Airport (PHX) to La Florida Airport (LSC) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filters. Enter your dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from PHX to LSC?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Keep in mind that flight schedules can change depending on various factors, such as the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Sky Harbor Intl. Airport (PHX) to La Florida Airport (LSC)?
To avoid potential delays on the Sky Harbor Intl. Airport (PHX) to La Florida Airport (LSC) route, fly before 3 PM. Departures after this hour are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Sky Harbor Intl. Airport (PHX) to La Florida Airport (LSC) last-minute?
Booking your plane ticket from PHX to LSC shortly before your getaway is typically more expensive. However, if you're flexible with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a PHX to LSC flight and hotel package?
Compared with arranging flights and hotels separately, booking a PHX to LSC flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one easy place will take the hassle out of planning your trip. Just secure your flights and select from our wide range of hotels, then tailor your trip with other add-ons like activities, tours and car rentals.
Can I cancel or change the date of my flight from Sky Harbor Intl. Airport (PHX) to La Florida Airport (LSC)?
In most cases, you can modify or cancel your PHX to LSC flight. However, additional fees may apply, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline's rules and fees on flight changes, or if you want further information, head to our Customer Service portal.

Travel information

Origin airport
Sky Harbor Intl.
Destination airport
La Florida
Roundtrip price
$1,471
Distance
5124 mi

Book with confidence

Phoenix to La Serena Flights

The cheapest times to fly from Phoenix to La Serena

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Phoenix to La Serena are during the month of March. You can find some of the cheapest flights from Phoenix to La Serena with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Phoenix to La Serena

Sunday is one of the best days to book for cheap flights from Phoenix to La Serena: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Phoenix to La Serena

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Phoenix to La Serena in 2026. You can also book with separate airlines for your outbound and return journeys, from $512 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Phoenix to La Serena flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Phoenix to La Serena airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Phoenix to La Serena Flights

*Flight schedules are subject to change.

Explore a world of travel with Expedia

*Available to One Key members.