$392 Cheap Flights from Los Angeles (LAX) to La Serena (LSC)

View $392 flight on Tue, Nov 18, 2025Opens in a new window

Popular airlines from Los Angeles Intl. (LAX) to La Serena (LSC-La Florida)

Cheap Flights from Los Angeles to La Serena (LAX-LSC)

Prices were available within the past 7 days and start at $392 for one-way flights and $834 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Sun, Nov 9 - Tue, Nov 11
LAX
Los Angeles
LSC
La Serena
$834 Roundtrip, found 6 days ago
$834
Roundtrip
found 6 days ago
Select Delta flight, departing Sun, Nov 9 from Los Angeles to La Serena, returning Tue, Nov 11, priced at $834 found 6 days ago
LATAM Airlines Group
Sun, Nov 9 - Wed, Nov 12
LAX
Los Angeles
LSC
La Serena
$844 Roundtrip, found 6 days ago
$844
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Sun, Nov 9 from Los Angeles to La Serena, returning Wed, Nov 12, priced at $844 found 6 days ago
LATAM Airlines Group
Sun, Nov 9 - Fri, Nov 14
LAX
Los Angeles
LSC
La Serena
$849 Roundtrip, found 6 days ago
$849
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Sun, Nov 9 from Los Angeles to La Serena, returning Fri, Nov 14, priced at $849 found 6 days ago
LATAM Airlines Group
Mon, Nov 3 - Wed, Nov 12
LAX
Los Angeles
LSC
La Serena
$917 Roundtrip, found 2 days ago
$917
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, Nov 3 from Los Angeles to La Serena, returning Wed, Nov 12, priced at $917 found 2 days ago
Delta
Thu, Nov 6 - Tue, Nov 11
LAX
Los Angeles
LSC
La Serena
$921 Roundtrip, found 6 days ago
$921
Roundtrip
found 6 days ago
Select Delta flight, departing Thu, Nov 6 from Los Angeles to La Serena, returning Tue, Nov 11, priced at $921 found 6 days ago
LATAM Airlines Group
Mon, Nov 3 - Fri, Nov 14
LAX
Los Angeles
LSC
La Serena
$922 Roundtrip, found 2 days ago
$922
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, Nov 3 from Los Angeles to La Serena, returning Fri, Nov 14, priced at $922 found 2 days ago
LATAM Airlines Group
Mon, Nov 3 - Wed, Nov 19
LAX
Los Angeles
LSC
La Serena
$931 Roundtrip, found 2 days ago
$931
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, Nov 3 from Los Angeles to La Serena, returning Wed, Nov 19, priced at $931 found 2 days ago
LATAM Airlines Group
Fri, Nov 7 - Fri, Nov 14
LAX
Los Angeles
LSC
La Serena
$931 Roundtrip, found 6 days ago
$931
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Fri, Nov 7 from Los Angeles to La Serena, returning Fri, Nov 14, priced at $931 found 6 days ago
LATAM Airlines Group
Mon, Nov 3 - Sat, Nov 15
LAX
Los Angeles
LSC
La Serena
$932 Roundtrip, found 2 days ago
$932
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, Nov 3 from Los Angeles to La Serena, returning Sat, Nov 15, priced at $932 found 2 days ago
LATAM Airlines Group
Sat, Nov 8 - Fri, Nov 14
LAX
Los Angeles
LSC
La Serena
$936 Roundtrip, found 6 days ago
$936
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Sat, Nov 8 from Los Angeles to La Serena, returning Fri, Nov 14, priced at $936 found 6 days ago
Flights from Los Angeles (LAX) to La Serena (LSC)
Origin airport
Los Angeles Intl.
Destination airport
La Florida
Airlines serving
LATAM Airlines Group
Roundtrip price
$834
Distance
5380 mi

Los Angeles to La Serena Flights

The cheapest times to fly from Los Angeles to La Serena

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Los Angeles to La Serena are during the month of November. You can find some of the cheapest flights from Los Angeles to La Serena with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Los Angeles to La Serena

Sunday is one of the best days to book for cheap flights from Los Angeles to La Serena: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Los Angeles to La Serena

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Los Angeles to La Serena in 2025. You can also book with separate airlines for your outbound and return journeys, from $392 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Los Angeles to La Serena flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Los Angeles to La Serena airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Los Angeles Intl. Airport (LAX) to La Florida Airport (LSC) cost?
Get a cheap one-way flight from $392 or cheap return flight from $834 from Los Angeles Intl. Airport (LAX) to La Florida Airport (LSC) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Los Angeles Intl. Airport (LAX) to La Florida Airport (LSC)?
Planning your getaway for November can help you save, as it's the cheapest month for flights between LAX and LSC. You'll usually find the lowest prices during the off-season.
What is the cheapest airline that flies from Los Angeles Intl. Airport (LAX) to La Florida Airport (LSC)?
To find the cheapest airline flying from LAX to LSC, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Los Angeles Intl. Airport (LAX) to La Florida Airport (LSC)?
There are no daily direct flights available from Los Angeles Intl. Airport (LAX) to La Florida Airport (LSC). But you can book flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be soaring above the clouds before you know it.
What day of the week has the most flights from LAX to LSC?
Typically you'll find the most flight options available on a Friday. Tuesdays tend to be the quietest.* However, this can vary depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Los Angeles Intl. Airport (LAX) to La Florida Airport (LSC)?
To avoid potential delays on the Los Angeles Intl. Airport (LAX) to La Florida Airport (LSC) route, aim to fly before 3 PM. Later departures have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Los Angeles Intl. Airport (LAX) to La Florida Airport (LSC) last-minute?
Holding off until just before your trip to book a flight from LAX to LSC often results in higher prices. While you may find some last-minute offers, they're not always guaranteed. Allow some flexibility in your schedule to boost your chances of snagging a bargain.
Is it cheaper to book a LAX to LSC flight and hotel package?
Booking a LAX to LSC flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Select from our wide range of accommodations and then add flights, car rentals and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Los Angeles Intl. Airport (LAX) to La Florida Airport (LSC)?
Typically, you're able to reschedule or cancel your LAX to LSC flight. However, there may be additional fees, especially if you booked over 24 hours ago. Double-check your itinerary for the airline's fees and guidelines on flight changes, or if you want further details, go to our Customer Service portal.

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*Available to One Key members.