$416 Cheap Flights from Pisa (PSA) to Charleston (CHS)

View $416 flight on Tue, Nov 11, 2025Opens in a new window

Popular airlines from Galileo Galilei Airport (PSA) to Charleston Intl. Airport (CHS)

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Cheap Flights from Pisa to Charleston (PSA-CHS)

Prices were available within the past 7 days and start at $416 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frequently asked questions

How much does a flight from Galileo Galilei Airport (PSA) to Charleston Intl. Airport (CHS) cost?
Snag a cheap one-way flight from $416 or cheap return flight from Galileo Galilei Airport (PSA) to Charleston Intl. Airport (CHS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Galileo Galilei Airport (PSA) to Charleston Intl. Airport (CHS)?
Flying in can help you save, as it's the cheapest month for flights between PSA and CHS. You'll usually find the lowest fares during off-peak months.
What is the cheapest airline that flies from Galileo Galilei Airport (PSA) to Charleston Intl. Airport (CHS)?
Use the filter tool on Expedia to compare different airlines and find the most affordable carrier that'll fly you from PSA to CHS. Then, sort your results by "Price (lowest to highest)" to snag the best deal available.
How many flights per day from Galileo Galilei Airport (PSA) to Charleston Intl. Airport (CHS)?
Nonstop flights from Galileo Galilei Airport (PSA) to Charleston Intl. Airport (CHS) aren't available daily, so you'll have to take a flight with a layover. Explore your options with our filter tool. Enter your travel details and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from PSA to CHS?
Generally you'll find the greatest selection of flight options on a Friday. Tuesdays are often the quietest.* However, this can change based on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Galileo Galilei Airport (PSA) to Charleston Intl. Airport (CHS)?
Book a flight from Galileo Galilei Airport (PSA) to Charleston Intl. Airport (CHS) that takes off before 3 PM to reduce the risk of cancellations. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Galileo Galilei Airport (PSA) to Charleston Intl. Airport (CHS) last-minute?
Booking your ticket from PSA to CHS right before your trip is usually more expensive. However, if there's some wiggle room with your departure times and dates, you could bag a cheap last-minute fare.
Is it cheaper to book a PSA to CHS flight and hotel package?
Compared with arranging hotels and flights separately, booking a PSA to CHS flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one convenient place takes the hassle out of planning your trip. Simply secure your flights and choose from our extensive range of hotels, then personalize your trip with extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Galileo Galilei Airport (PSA) to Charleston Intl. Airport (CHS)?
Typically, it's possible to cancel or reschedule your PSA to CHS flight. However, for bookings made more than 24 hours ago, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Travel information

Origin airport
Galileo Galilei
Destination airport
Charleston Intl.
Distance
4715 mi

Book with confidence

Book with confidence

Pisa to Charleston Flights

The cheapest times to fly from Pisa to Charleston

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Pisa to Charleston are during the month of . You can find some of the cheapest flights from Pisa to Charleston with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Pisa to Charleston

Sunday is one of the best days to book for cheap flights from Pisa to Charleston: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Pisa to Charleston

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Pisa to Charleston in 2025. You can also book with separate airlines for your outbound and return journeys, from $416 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Pisa to Charleston flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Pisa to Charleston airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Pisa to Charleston Flights

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*Available to One Key members.