$279 Cheap Flights from Ponce (PSE) to Santo Domingo (SDQ)

View $279 flight on Fri, Oct 3, 2025Opens in a new window

Popular airlines from Ponce (PSE-Mercedita) to Las Americas Intl. Airport (SDQ)

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Cheap Flights from Ponce to Santo Domingo (PSE-SDQ)

Prices were available within the past 7 days and start at $279 for one-way flights and $410 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Wed, Oct 29 - Fri, Nov 14
PSE
Ponce
SDQ
Santo Domingo
$410 Roundtrip, found 5 days ago
$410
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Wed, Oct 29 from Ponce to Santo Domingo, returning Fri, Nov 14, priced at $410 found 5 days ago
JetBlue Airways
Wed, Nov 5 - Thu, Nov 20
PSE
Ponce
SDQ
Santo Domingo
$421 Roundtrip, found 11 hours ago
$421
Roundtrip
found 11 hours ago
Select JetBlue Airways flight, departing Wed, Nov 5 from Ponce to Santo Domingo, returning Thu, Nov 20, priced at $421 found 11 hours ago
JetBlue Airways
Wed, Nov 5 - Sat, Nov 22
PSE
Ponce
SDQ
Santo Domingo
$423 Roundtrip, found 11 hours ago
$423
Roundtrip
found 11 hours ago
Select JetBlue Airways flight, departing Wed, Nov 5 from Ponce to Santo Domingo, returning Sat, Nov 22, priced at $423 found 11 hours ago
JetBlue Airways
Wed, Nov 5 - Fri, Nov 14
PSE
Ponce
SDQ
Santo Domingo
$426 Roundtrip, found 2 days ago
$426
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Wed, Nov 5 from Ponce to Santo Domingo, returning Fri, Nov 14, priced at $426 found 2 days ago
JetBlue Airways
Wed, Oct 29 - Wed, Nov 12
PSE
Ponce
SDQ
Santo Domingo
$450 Roundtrip, found 5 days ago
$450
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Wed, Oct 29 from Ponce to Santo Domingo, returning Wed, Nov 12, priced at $450 found 5 days ago
JetBlue Airways
Wed, Nov 5 - Wed, Nov 12
PSE
Ponce
SDQ
Santo Domingo
$451 Roundtrip, found 2 days ago
$451
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Wed, Nov 5 from Ponce to Santo Domingo, returning Wed, Nov 12, priced at $451 found 2 days ago
JetBlue Airways
Wed, Oct 29 - Thu, Nov 13
PSE
Ponce
SDQ
Santo Domingo
$456 Roundtrip, found 5 days ago
$456
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Wed, Oct 29 from Ponce to Santo Domingo, returning Thu, Nov 13, priced at $456 found 5 days ago
JetBlue Airways
Tue, Nov 18 - Sat, Nov 22
PSE
Ponce
SDQ
Santo Domingo
$463 Roundtrip, found 6 hours ago
$463
Roundtrip
found 6 hours ago
Select JetBlue Airways flight, departing Tue, Nov 18 from Ponce to Santo Domingo, returning Sat, Nov 22, priced at $463 found 6 hours ago
JetBlue Airways
Fri, Oct 24 - Fri, Nov 14
PSE
Ponce
SDQ
Santo Domingo
$465 Roundtrip, found 3 days ago
$465
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Fri, Oct 24 from Ponce to Santo Domingo, returning Fri, Nov 14, priced at $465 found 3 days ago
JetBlue Airways
Wed, Nov 5 - Tue, Nov 18
PSE
Ponce
SDQ
Santo Domingo
$466 Roundtrip, found 11 hours ago
$466
Roundtrip
found 11 hours ago
Select JetBlue Airways flight, departing Wed, Nov 5 from Ponce to Santo Domingo, returning Tue, Nov 18, priced at $466 found 11 hours ago

Frequently asked questions

How much does a flight from Mercedita Airport (PSE) to Las Americas Intl. Airport (SDQ) cost?
Grab a cheap one-way flight from $279 or cheap return flight from $410 from Mercedita Airport (PSE) to Las Americas Intl. Airport (SDQ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Mercedita Airport (PSE) to Las Americas Intl. Airport (SDQ)?
Planning your trip for October can help you save, as it's the cheapest month for flights between PSE and SDQ. You'll often find the lowest fares during the off-season.
Which airlines fly direct from Mercedita Airport (PSE) to Las Americas Intl. Airport (SDQ)?
There are no direct routes from Ponce (PSE-Mercedita) to Las Americas Intl. Airport (SDQ). However, there are other airports with nonstop flights. Start your journey at Luis Munoz Marin Intl. Airport (SJU) and head straight to Santo Domingo without layovers.
What is the cheapest airline that flies from Mercedita Airport (PSE) to Las Americas Intl. Airport (SDQ)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest PSE to SDQ flight.
How many flights per day from Mercedita Airport (PSE) to Las Americas Intl. Airport (SDQ)?
You'll have to hop on a flight with a layover when traveling from Mercedita Airport (PSE) to Las Americas Intl. Airport (SDQ). There are no daily direct flights on this route. However, just filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from PSE to SDQ?
You'll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Mercedita Airport (PSE) to Las Americas Intl. Airport (SDQ)?
To land at Las Americas Intl. Airport (SDQ) on time, opt for a flight that leaves Mercedita Airport (PSE) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Mercedita Airport (PSE) to Las Americas Intl. Airport (SDQ) last-minute?
Waiting until just before your departure to book a ticket from PSE to SDQ often results in higher prices. While you may find some last-minute deals, they're not always guaranteed. Allow some flexibility in your schedule to boost your chances of scoring a bargain.
Is it cheaper to book a PSE to SDQ flight and hotel package?
You'll generally save money by booking a PSE to SDQ flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one convenient place. Once you've chosen your ideal accommodations and flights, consider adding extras including car rentals, tours and activities.
Can I cancel or change the date of my flight from Mercedita Airport (PSE) to Las Americas Intl. Airport (SDQ)?
If you reserved your PSE to SDQ flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the ticket type you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you'd like more information.

Travel information

Travel information

Origin airport
Mercedita
Destination airport
Las Americas Intl.
Airlines serving
JetBlue Airways
Roundtrip price
$410
Distance
206 mi

Book with confidence

Book with confidence

Ponce to Santo Domingo Flights

The cheapest times to fly from Ponce to Santo Domingo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Ponce to Santo Domingo are during the month of October. You can find some of the cheapest flights from Ponce to Santo Domingo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Ponce to Santo Domingo

Sunday is one of the best days to book for cheap flights from Ponce to Santo Domingo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Ponce to Santo Domingo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Ponce to Santo Domingo in 2025. You can also book with separate airlines for your outbound and return journeys, from $279 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Ponce to Santo Domingo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Ponce to Santo Domingo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Ponce to Santo Domingo Flights

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*Available to One Key members.