$231 Cheap Flights from Santiago (STI) to Panama City (ECP)

View $231 flight on Wed, Dec 3, 2025Opens in a new window

Popular airlines from Cibao Intl. Airport (STI) to Northwest Florida Beaches Intl. Airport (ECP)

Cheap Flights from Santiago to Panama City (STI-ECP)

Prices were available within the past 7 days and start at $231 for one-way flights and $591 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Jul 7 - Tue, Jul 14
STI
Santiago de los Caballeros
ECP
Panama City
$591 Roundtrip, found 4 hours ago
$591
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Jul 7 from Santiago de los Caballeros to Panama City, returning Tue, Jul 14, priced at $591 found 4 hours ago
American Airlines
Tue, Jul 7 - Tue, Jul 14
STI
Santiago de los Caballeros
ECP
Panama City
$599 Roundtrip, found 4 hours ago
$599
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Jul 7 from Santiago de los Caballeros to Panama City, returning Tue, Jul 14, priced at $599 found 4 hours ago
American Airlines
Tue, Jul 7 - Tue, Jul 14
STI
Santiago de los Caballeros
ECP
Panama City
$600 Roundtrip, found 4 hours ago
$600
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Jul 7 from Santiago de los Caballeros to Panama City, returning Tue, Jul 14, priced at $600 found 4 hours ago
American Airlines
Tue, Jul 7 - Tue, Jul 14
STI
Santiago de los Caballeros
ECP
Panama City
$656 Roundtrip, found 4 hours ago
$656
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Jul 7 from Santiago de los Caballeros to Panama City, returning Tue, Jul 14, priced at $656 found 4 hours ago
Delta
Tue, Jul 7 - Tue, Jul 14
STI
Santiago de los Caballeros
ECP
Panama City
$659 Roundtrip, found 4 hours ago
$659
Roundtrip
found 4 hours ago
Select Delta flight, departing Tue, Jul 7 from Santiago de los Caballeros to Panama City, returning Tue, Jul 14, priced at $659 found 4 hours ago
American Airlines
Tue, Jul 7 - Tue, Jul 14
STI
Santiago de los Caballeros
ECP
Panama City
$665 Roundtrip, found 4 hours ago
$665
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Jul 7 from Santiago de los Caballeros to Panama City, returning Tue, Jul 14, priced at $665 found 4 hours ago
American Airlines
Tue, Jul 7 - Tue, Jul 14
STI
Santiago de los Caballeros
ECP
Panama City
$666 Roundtrip, found 4 hours ago
$666
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Jul 7 from Santiago de los Caballeros to Panama City, returning Tue, Jul 14, priced at $666 found 4 hours ago
American Airlines
Tue, Jul 7 - Tue, Jul 14
STI
Santiago de los Caballeros
ECP
Panama City
$668 Roundtrip, found 4 hours ago
$668
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Jul 7 from Santiago de los Caballeros to Panama City, returning Tue, Jul 14, priced at $668 found 4 hours ago
American Airlines
Tue, Jul 7 - Tue, Jul 14
STI
Santiago de los Caballeros
ECP
Panama City
$674 Roundtrip, found 4 hours ago
$674
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Jul 7 from Santiago de los Caballeros to Panama City, returning Tue, Jul 14, priced at $674 found 4 hours ago
Delta
Tue, Jul 7 - Tue, Jul 14
STI
Santiago de los Caballeros
ECP
Panama City
$679 Roundtrip, found 4 hours ago
$679
Roundtrip
found 4 hours ago
Select Delta flight, departing Tue, Jul 7 from Santiago de los Caballeros to Panama City, returning Tue, Jul 14, priced at $679 found 4 hours ago

Frequently asked questions

How much does a flight from Cibao Intl. Airport (STI) to Northwest Florida Beaches Intl. Airport (ECP) cost?
Snag a cheap one-way flight from $231 or cheap return flight from $591 from Cibao Intl. Airport (STI) to Northwest Florida Beaches Intl. Airport (ECP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Cibao Intl. Airport (STI) to Northwest Florida Beaches Intl. Airport (ECP)?
July is the least expensive month to fly from STI to ECP. Timing your trip outside of the busy season is often the key to scoring lower fares.
What is the cheapest airline that flies from Cibao Intl. Airport (STI) to Northwest Florida Beaches Intl. Airport (ECP)?
To find the cheapest airline that'll fly you from STI to ECP, use Expedia's filter tool. Customize your search based on your travel style, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Cibao Intl. Airport (STI) to Northwest Florida Beaches Intl. Airport (ECP)?
There aren't any daily nonstop flights from Cibao Intl. Airport (STI) to Northwest Florida Beaches Intl. Airport (ECP). But you can opt for flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be soaring above the clouds in no time.
What day of the week has the most flights from STI to ECP?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Cibao Intl. Airport (STI) to Northwest Florida Beaches Intl. Airport (ECP)?
Book a flight from Cibao Intl. Airport (STI) to Northwest Florida Beaches Intl. Airport (ECP) that takes off before 3 PM to reduce the risk of cancellations and delays. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Cibao Intl. Airport (STI) to Northwest Florida Beaches Intl. Airport (ECP) last-minute?
Waiting until right before your break to book a flight from STI to ECP often results in higher prices. While it's possible to find some last-minute discounts, they're not always guaranteed. Be flexible with your travel plans for the best chance of getting a bargain.
Is it cheaper to book a STI to ECP flight and hotel package?
Booking a STI to ECP flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Pick from our wide range of accommodations and then add activities, flights and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Cibao Intl. Airport (STI) to Northwest Florida Beaches Intl. Airport (ECP)?
In most instances, you're able to reschedule or cancel your STI to ECP flight. However, there may be additional fees, especially if you booked over 24 hours ago. Double-check your itinerary for the airline's fees and guidelines on flight changes, or if you'd like further details, go to our Customer Service portal.

Travel information

Origin airport
Cibao Intl.
Destination airport
Northwest Florida Beaches Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$591
Distance
1214 mi

Book with confidence

Santiago to Panama City Flights

The cheapest times to fly from Santiago to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santiago to Panama City are during the month of July. You can find some of the cheapest flights from Santiago to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santiago to Panama City

Sunday is one of the best days to book for cheap flights from Santiago to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santiago to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santiago to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $231 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santiago to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santiago to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santiago to Panama City Flights

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*Available to One Key members.