Title: The Best 5 Star Hotels in Hyannis, MA from $148 | Expedia.com [Hyannis Travel Guide](https://expedia.com/Hyannis.dx1544)[Hotels in Hyannis](https://expedia.com/Hyannis-Hotels.d1544.Travel-Guide-Hotels)[Vacation Rentals in Hyannis](https://expedia.com/Hyannis-Vacation-Rentals.d1544.Travel-Guide-VacationRentals)[Flights to Hyannis](https://expedia.com/Cheap-Flights-To-Hyannis.d1544.Travel-Guide-Flights)[Things to do in Hyannis](https://expedia.com/Things-To-Do-In-Hyannis.d1544.Travel-Guide-Activities)[Car Rentals in Hyannis](https://expedia.com/Car-Rentals-In-Hyannis.d1544.Car-Rental-Guide)[Hyannis Vacation Packages](https://expedia.com/Hyannis.d1544.Destination-Travel-Guides) ![Hyannis showing a marina and a bay or harbor](https://images.trvl-media.com/place/553248635146342095/727e0fd8-4e19-4ca2-997d-3604702ab1c6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248635146342095/727e0fd8-4e19-4ca2-997d-3604702ab1c6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Hyannis 5 Star Hotels Tonight [Feb 7 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=1544&startDate=2026-02-07&endDate=2026-02-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 8 - Feb 9](https://www.expedia.com/Hotel-Search?regionId=1544&startDate=2026-02-08&endDate=2026-02-09&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=1544&startDate=2026-02-13&endDate=2026-02-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=1544&startDate=2026-02-20&endDate=2026-02-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Hyannis 5-star hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19200/19139/13fe4b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19200/19139/c3fa2de8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19200/19139/efc614b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, body treatments, aromatherapy](https://images.trvl-media.com/lodging/1000000/20000/19200/19139/w5695h3900x5y0-3649fa2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Chatham Bars Inn [](https://www.expedia.com/Chatham-Hotels-Chatham-Bars-Inn.h19139.Hotel-Information) Chatham 9.2/10 Wonderful (809 reviews) "Beautiful property " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric $364 nightly $417 total Feb 11 - Feb 12 Total with taxes and fees [](https://www.expedia.com/Chatham-Hotels-Chatham-Bars-Inn.h19139.Hotel-Information) ![Round Cove Suite | Frette Italian sheets, premium bedding, down comforters, minibar](https://images.trvl-media.com/lodging/1000000/10000/3700/3689/ce420299.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, down comforters, minibar](https://images.trvl-media.com/lodging/1000000/10000/3700/3689/2c23c623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Room, 1 King Bed | Frette Italian sheets, premium bedding, down comforters, minibar](https://images.trvl-media.com/lodging/1000000/10000/3700/3689/58f6c718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3700/3689/bf11cab5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wequassett Resort and Golf Club [](https://www.expedia.com/Harwich-Hotels-Wequassett-Resort-And-Golf-Club.h3689.Hotel-Information) Harwich 9.4/10 Exceptional (244 reviews) "The staff is amazing, they are kind and always looking for ways to help and make you feel welcome." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karla $330 nightly $378 total Feb 18 - Feb 19 Total with taxes and fees [](https://www.expedia.com/Harwich-Hotels-Wequassett-Resort-And-Golf-Club.h3689.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Hyannis-Hotels.s50-0-d1544.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Hyannis-Hotels.s50-0-d1544.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Hyannis. ![Margaritaville Resort Cape Cod](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/b57e0b1f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Margaritaville Resort Cape Cod 1225 Iyannough Rd Hyannis MA $208 nightly $238 total Feb 10 - Feb 11 Total with taxes and fees 8.6/10 Excellent! (441 reviews) [](https://expedia.com/Hyannis-Hotels-Cape-Codder-Resort-And-Spa.h12897.Hotel-Information) ![Chatham Wayside Inn](https://images.trvl-media.com/lodging/2000000/1520000/1517300/1517204/1adc0002_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Chatham Wayside Inn 512 Main St Chatham MA $172 nightly $197 total Feb 22 - Feb 23 Total with taxes and fees 9.2/10 Wonderful! (629 reviews) [](https://expedia.com/Chatham-Hotels-Chatham-Wayside-Inn.h1517204.Hotel-Information) ![Doubletree by Hilton Cape Cod - Hyannis](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/9f940314_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Doubletree by Hilton Cape Cod - Hyannis 287 Iyannough Rd Hyannis MA $130 nightly $148 total Feb 22 - Feb 23 Total with taxes and fees 8.2/10 Very Good! (888 reviews) [](https://expedia.com/Hyannis-Hotels-Doubletree-By-Hilton-Cape-Cod-Hyannis.h40461.Hotel-Information) Still don't see what you're looking for? [See all properties in Hyannis.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F8%2F2026&endDate=2%2F9%2F2026®ionId=1544&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F8%2F2026&endDate=2%2F9%2F2026®ionId=1544&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F8%2F2026&endDate=2%2F9%2F2026®ionId=1544&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F8%2F2026&endDate=2%2F9%2F2026®ionId=1544&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F8%2F2026&endDate=2%2F9%2F2026®ionId=1544&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F8%2F2026&endDate=2%2F9%2F2026®ionId=1544&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Hyannis Stroll the bustling harbor and hop aboard a ferry to Martha's Vineyard or Nantucket for a day trip. Visit the John F. Kennedy Hyannis Museum to learn about the president's connection to Cape Cod's summer playground. [See all hotels in Hyannis](https://www.expedia.com/Hotel-Search?startDate=2026-02-21&endDate=2026-02-22&adults=2®ionId=1544) ![Hyannis showing a marina and a bay or harbor](https://images.trvl-media.com/place/553248635146342095/727e0fd8-4e19-4ca2-997d-3604702ab1c6.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Hyannis Hotel Reviews ![Chatham Bars Inn](https://images.trvl-media.com/lodging/1000000/20000/19200/19139/w5700h3895x0y5-016d240d_y.jpg) ### Chatham Bars Inn 10/10 Excellent "Beautiful property " [](https://expedia.com/Chatham-Hotels-Chatham-Bars-Inn.h19139.Hotel-Information) ## Find out more about Hyannis There's nothing wrong with enjoying the finer things in life. Treat your every whim on your impending break. There's no reason to delay a getaway to Hyannis any longer. You'll join the multitudes of vacationers who have made Hyannis so fashionable in the last year. The hotels in Hyannis also offer great customer service, averaging 3.7 in our ranking system, giving you a lot to look forward to. Don't wait any longer. Reserve one of our 5-star hotels in Hyannis and indulge in the finer things in life for a while. ### Get a Great Deal on 5-Star Hotels in Hyannis You can expect superior customer service from your hotel. Excellent customer care, luxurious bedding, and fabulous spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You'll be pleased to note that the hotels in Hyannis offer great customer service, averaging 3.7 in our ranking system, setting you up for a truly relaxing getaway. How do you want to relax? 24-hour room service, so you can order that filet mignon in the wee hours of the morning? A body scrub that will leave you feeling outstanding? Butler services? No matter what you want on a perfect getaway, you're bound to find it here. Don't want to take our word for it? Then explore the 551 reviews various guests have left on Expedia and get to know these places. Yearning for experiences outside your hotel room? We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Hyannis are waiting for you to relax after an exciting day. ### Make Your Escape The results are in, and Hyannis 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. Don't put off your dream vacation any longer -- Expedia can help you land a great deal on accommodation. Opt for one of our Hyannis 5-star hotels today and decompress in complete comfort when you're ready. ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Hyannis? > - Search for the lowest price per night from $148 ### What makes a hotel 5 stars in Hyannis? ### Are there any 5-star all-inclusive resorts in Hyannis? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - [Cape Cod Hotels ](https://www.expedia.com/Cape-Cod-Hotels.d180061.Travel-Guide-Hotels) - [Hotels with an Indoor Pool in Barnstable County ](https://www.expedia.com/Destinations-In-Barnstable-County-Hotels-With-Indoor-Pool.0-0-d553248635976434260-tHotelswithIndoorPool.Hotel-Filter-Destinations) - [Luxury Hotels in Barnstable County ](https://www.expedia.com/Destinations-In-Barnstable-County-Luxury-Hotel.0-0-d553248635976434260-tLuxuryHotel.Hotel-Filter-Destinations) - [Pet-friendly Hotels in Barnstable County ](https://www.expedia.com/Destinations-In-Barnstable-County-Pet-Friendly-Hotel.0-0-d553248635976434260-tPetfriendlyHotel.Hotel-Filter-Destinations) - [Cheap Hotels in Barnstable County ](https://www.expedia.com/Destinations-In-Barnstable-County-Cheap-Hotels.0-0-d553248635976434260-tCheapHotels.Hotel-Filter-Destinations) - [Barnstable County Hotels ](https://www.expedia.com/Destinations-In-Barnstable-County.d553248635976434260.Hotel-Destinations) - [B&B in Barnstable County ](https://www.expedia.com/Barnstable-County-Bed-And-Breakfast.d553248635976434260-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels near John F. 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Kennedy Hyannis Museum ](https://www.expedia.com/John-F-Kennedy-Hyannis-Museum-Hyannis.d6070185.Vacation-Attraction) - [Cape Cod Baseball Hall of Fame ](https://www.expedia.com/Cape-Cod-Baseball-Hall-Of-Fame-Hyannis.d6287117.Vacation-Attraction) - [Cape Cod Maritime Museum ](https://www.expedia.com/Cape-Cod-Maritime-Museum-Hyannis.d553248635146342095.Vacation-Attraction) - [Hyannis Harbor ](https://www.expedia.com/Hyannis-Harbor-Hyannis.d6127091.Vacation-Attraction) - [St. Francis Xavier Church ](https://www.expedia.com/St-Francis-Xavier-Church-Hyannis.d6286986.Vacation-Attraction) - [Wackenhammer's Clockwork Arcade ](https://www.expedia.com/Wackenhammers-Clockwork-Arcade-Hyannis.d553248621555594681.Vacation-Attraction) - [Commotion Charters ](https://www.expedia.com/Commotion-Charters-Hyannis.d553248621532666521.Vacation-Attraction) - [John F. Kennedy Memorial ](https://www.expedia.com/John-F-Kennedy-Memorial-Hyannis.d6286978.Vacation-Attraction) - [Wild Animal Lagoon ](https://www.expedia.com/Wild-Animal-Lagoon-West-Yarmouth.d6286727.Vacation-Attraction) - [Veterans Memorial Park ](https://www.expedia.com/Veterans-Memorial-Park-Hyannis.d553248621532666520.Vacation-Attraction) - [Car rentals near Main Street Hyannis ](https://www.expedia.com/Car-Rentals-In-Main-Street-Hyannis.d6287458.Car-Rental-Guide) - [Car rentals near Wild Animal Lagoon ](https://www.expedia.com/Car-Rentals-In-Wild-Animal-Lagoon.d6286727.Car-Rental-Guide) - [Enterprise Rental Cars in Barnstable Municipal ](https://www.expedia.com/Enterprise-Car-Rentals-In-Barnstable-Municipal.d6028491-c15.Car-Rental-Guide-Suppliers) - [Avis Rental Cars in Barnstable Municipal ](https://www.expedia.com/Avis-Car-Rentals-In-Barnstable-Municipal.d6028491-c41.Car-Rental-Guide-Suppliers) - [Things to do in Barnstable County ](https://www.expedia.com/Things-To-Do-In-Barnstable-County.d553248635976434260.Travel-Guide-Activities)