---
title: "Des Moines to Hyannis cheap flights from $473 (DSM to HYA) - Expedia"
description: "Compare cheap Flights from Des Moines (DSM) to Hyannis (HYA) start at $473 for one-way and $1,141 for round trip. Earn your airline miles on top of our rewards!"
canonical: "https://www.expedia.com/lp/flights/dsm/hya/des-moines-to-hyannis"
language: en-US
market: US
currency: USD
prices_as_of: 2026-11-15T18:03:49Z
---

# $473 Cheap Flights from Des Moines (DSM) to Hyannis (HYA)
![A marina with several boats docked, a lifebuoy attached to a dock, and a clear blue sky.](https://images.trvl-media.com/place/1544/de531aac-28f7-4343-89ee-793f602afd23.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

[View $473 flight on Wed, Nov 25, 2026](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:HYA,departure:11/25/2026TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:472.70&airProductToken=AQqaAQo1CMSYARIEMjA4NhjDZCDgXCi0kp4DMLOTngM4VkAAWAFqCU1BSU5DTEFTQ3IIVkFVTkEwTUUKNQjEmAESAzg2NRjgXCDBkwEo3JOeAzDwlJ4DOFZAAVgBaglNQUlOQ0xBU0NyCFZBVU5BME1FCioIuZYBEgQ3MDcxGMGTASCHBiiqmJ4DMNeYngM4VkABWAFqAkVScgNWSVASDAgBEAEYASoCREwyABgBIgQIARABKAIoAygEMAE)

## Popular airlines from Des Moines International Airport (DSM) to Hyannis, MA (HYA-Barnstable Municipal)

[American Airlines](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:HYA,departure:11/29/2026TANYT&leg2=from:HYA,to:DSM,departure:12/6/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}])

[United](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:HYA,departure:11/29/2026TANYT&leg2=from:HYA,to:DSM,departure:12/6/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}])

[Southwest Airlines](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:HYA,departure:11/29/2026TANYT&leg2=from:HYA,to:DSM,departure:12/6/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"WN"}}])

[Delta](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:HYA,departure:11/29/2026TANYT&leg2=from:HYA,to:DSM,departure:12/6/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}])

[Frontier Airlines](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:HYA,departure:11/29/2026TANYT&leg2=from:HYA,to:DSM,departure:12/6/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"F9"}}])

[JetBlue Airways](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:HYA,departure:11/29/2026TANYT&leg2=from:HYA,to:DSM,departure:12/6/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"B6"}}])

[Alaska Airlines](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:HYA,departure:11/29/2026TANYT&leg2=from:HYA,to:DSM,departure:12/6/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AS"}}])

## Cheap Flights from Des Moines to Hyannis (DSM-HYA)

Prices were available within the past 7 days and start at $473 for one-way flights and $1,141 for roundtrip, for the period specified. Prices and availability are subject to change.

All deals

One way

Roundtrip

[Select United flight, departing Wed, Nov 25 from Des Moines to Hyannis, returning Sun, Nov 29, priced at $1,141 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:HYA,departure:11/25/2026TANYT&leg2=from:HYA,to:DSM,departure:11/29/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1140.70&airProductToken=AQqXAQozCNWCARIEMjc3MBjDZCCuHCitkp4DMJCTngM4U0AAWAFqB0VDT05PTVlyCFNBQTRBS0ROCjQI1YIBEgQyMjk2GK4cIMGTASjIk54DMNqUngM4U0ABWAFqB0VDT05PTVlyCFNBQTRBS0ROCioIuZYBEgQ3MDcxGMGTASCHBiiqmJ4DMNeYngM4VkABWAFqAkVScgNWSVAKlgEKKgi5lgESBDcwNjEYhwYgwZMBKJy6ngMwybqeAzhWQABYAWoCRVJyA1ZJUAozCNWCARIDNTYzGMGTASCuHCiEvp4DMLy%5FngM4VUABWAFqB0VDT05PTVlyCFVBQTBBS0VOCjMI1YIBEgQxODM5GK4cIMNkKJHAngMw68CeAzhVQAFYAWoHRUNPTk9NWXIIVUFBMEFLRU4SDAgBEAEYASoCVUEyABgBIgQIARABKAIoAygEMAE)

Wed, Nov 25 - S · un, Nov 29 · DSM · HYA · Roundtrip

[Select United flight, departing Wed, Nov 25 from Des Moines to Hyannis, returning Sun, Nov 29, priced at $1,161 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:HYA,departure:11/25/2026TANYT&leg2=from:HYA,to:DSM,departure:11/29/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1160.70&airProductToken=AQqXAQozCNWCARIEMjc3MBjDZCCuHCitkp4DMJCTngM4U0AAWAFqB0VDT05PTVlyCFNBQTRBS0ROCjQI1YIBEgQyMjk2GK4cIMGTASjIk54DMNqUngM4U0ABWAFqB0VDT05PTVlyCFNBQTRBS0ROCioIuZYBEgQ3MDcxGMGTASCHBiiqmJ4DMNeYngM4VkABWAFqAkVScgNWSVAKlgEKKgi5lgESBDcxMDEYhwYgwZMBKP66ngMwsLueAzhCQABYAWoCRVJyA0JJUAozCNWCARIDNTYzGMGTASCuHCiEvp4DMLy%5FngM4VUABWAFqB0VDT05PTVlyCFVBQTBBS0VOCjMI1YIBEgQxODM5GK4cIMNkKJHAngMw68CeAzhVQAFYAWoHRUNPTk9NWXIIVUFBMEFLRU4SDAgBEAEYASoCVUEyABgBIgQIARABKAIoAygEMAE)

Wed, Nov 25 - Sun, Nov 29 · DSM · HYA · Roundtrip

[Select Delta flight, departing Wed, Nov 25 from Des Moines to Hyannis, returning Sun, Nov 29, priced at $1,171 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:HYA,departure:11/25/2026TANYT&leg2=from:HYA,to:DSM,departure:11/29/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1170.40&airProductToken=AQqaAQo1CMSYARIEMjA4NhjDZCDgXCi0kp4DMLOTngM4VkAAWAFqCU1BSU5DTEFTQ3IIVkFVTkEwTUUKNQjEmAESAzg2NRjgXCDBkwEo3JOeAzDwlJ4DOFZAAVgBaglNQUlOQ0xBU0NyCFZBVU5BME1FCioIuZYBEgQ3MDcxGMGTASCHBiiqmJ4DMNeYngM4VkABWAFqAkVScgNWSVASDAgBEAEYASoCREwyABgBIgQIARABKAIoAygEMAE)

Wed, Nov 25 - Sun, Nov 29 · DSM · HYA · Roundtrip

[Select Delta flight, departing Wed, Nov 25 from Des Moines to Hyannis, returning Sun, Nov 29, priced at $1,185 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:HYA,departure:11/25/2026TANYT&leg2=from:HYA,to:DSM,departure:11/29/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1184.80&airProductToken=AQqaAQo1CMSYARIEMjcyNxjDZCDgXCiSjJ4DMJWNngM4VkAAWAFqCU1BSU5DTEFTQ3IIVkFVTkEwTUUKNQjEmAESAzg1NRjgXCDBkwEo342eAzD8jp4DOFZAAVgBaglNQUlOQ0xBU0NyCFZBVU5BME1FCioIuZYBEgQ3MDMxGMGTASCHBiiVkJ4DMMKQngM4QkABWAFqAkVScgNCSVASDAgBEAEYASoCREwyABgBIgQIARABKAIoAygEMAE)

Wed, Nov 25 - Sun, Nov 29 · DSM · HYA · Roundtrip

[Select American Airlines flight, departing Wed, Nov 25 from Des Moines to Hyannis, returning Sun, Nov 29, priced at $1,201 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:HYA,departure:11/25/2026TANYT&leg2=from:HYA,to:DSM,departure:11/29/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1200.80&airProductToken=AQqTAQoxCMGCARIEMTk4NRjDZCDimgEo8oyeAzD9jZ4DOExAAFgBagRNQUlOcghMVUFaWk5OMQoyCMGCARIEMjYwOBjimgEgwZMBKL6OngMwwo-eAzhMQAFYAWoETUFJTnIITFVBWlpOTjEKKgi5lgESBDcwMzEYwZMBIIcGKJWQngMwwpCeAzhCQAFYAWoCRVJyA0JJUBIMCAEQARgBKgJBQTIAGAEiBAgBEAEoAigDKAQwAQ)

Wed, Nov 25 - Sun, Nov 29 · DSM · HYA · Roundtrip

[Select Delta flight, departing Wed, Nov 25 from Des Moines to Hyannis, returning Sun, Nov 29, priced at $1,221 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:HYA,departure:11/25/2026TANYT&leg2=from:HYA,to:DSM,departure:11/29/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1220.80&airProductToken=AQqdAQo2CMSYARIENTQxNBjDZCDjtAEovYyeAzCujZ4DOFhAAFgBaglNQUlOQ0xBU0NyCFhBVU9BME1FCjcIxJgBEgQyNjQ4GOO0ASDBkwEo5I2eAzDVjp4DOFhAAVgBaglNQUlOQ0xBU0NyCFhBVU9BME1FCioIuZYBEgQ3MDMxGMGTASCHBiiVkJ4DMMKQngM4QkABWAFqAkVScgNCSVASDAgBEAEYASoCREwyABgBIgQIARABKAIoAygEMAE)

Wed, Nov 25 - Sun, Nov 29 · DSM · HYA · Roundtrip

[Select Delta flight, departing Wed, Nov 25 from Des Moines to Hyannis, returning Sun, Nov 29, priced at $1,286 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:HYA,departure:11/25/2026TANYT&leg2=from:HYA,to:DSM,departure:11/29/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1285.80&airProductToken=AQqbAQo1CMSYARIENTQwMhjDZCDMfCjdjJ4DMKmNngM4VUAAWAFqCU1BSU5DTEFTQ3IIVUFVR0EwTVEKNgjEmAESBDI2NTUYzHwgwZMBKKqOngMwzo-eAzhVQAFYAWoJTUFJTkNMQVNDcghVQVVHQTBNUQoqCLmWARIENzAzMRjBkwEghwYolZCeAzDCkJ4DOEJAAVgBagJFUnIDQklQEgwIARABGAEqAkRMMgAYASIECAEQASgCKAMoBDAB)

Wed, Nov 25 - Sun, Nov 29 · DSM · HYA · Roundtrip

[Select United flight, departing Wed, Nov 25 from Des Moines to Hyannis, returning Sun, Nov 29, priced at $1,340 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:HYA,departure:11/25/2026TANYT&leg2=from:HYA,to:DSM,departure:11/29/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1339.69&airProductToken=AQqXAQozCNWCARIEMjY2OBjDZCCuHCiojZ4DMIyOngM4VUAAWAFqB0VDT05PTVlyCFVBQTdBRkVOCjQI1YIBEgQxNjA2GK4cIMGTASi-jp4DMM-PngM4VUABWAFqB0VDT05PTVlyCFVBQTdBRkVOCioIuZYBEgQ3MDMxGMGTASCHBiiVkJ4DMMKQngM4QkABWAFqAkVScgNCSVAKlwEKKgi5lgESBDcwNDEYhwYgwZMBKLW5ngMw57meAzhWQABYAWoCRVJyA1ZJUAo0CNWCARIEMjQ5NhjBkwEgrhwokb2eAzDJvp4DOFVAAVgBagdFQ09OT01ZcghVQUEwQUtFTgozCNWCARIEMTgzORiuHCDDZCiRwJ4DMOvAngM4VUABWAFqB0VDT05PTVlyCFVBQTBBS0VOEgwIARABGAEqAlVBMgAYASIECAEQASgCKAMoBDAB)

Wed, Nov 25 - Sun, Nov 29 · DSM · HYA · Roundtrip

[Select Delta flight, departing Wed, Nov 25 from Des Moines to Hyannis, returning Sun, Nov 29, priced at $1,357 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:HYA,departure:11/25/2026TANYT&leg2=from:HYA,to:DSM,departure:11/29/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1356.70&airProductToken=AQqaAQo1CMSYARIEMjA4NhjDZCDgXCi0kp4DMLOTngM4VkAAWAFqCU1BSU5DTEFTQ3IIVkFVTkEwTUUKNQjEmAESAzg2NRjgXCDBkwEo3JOeAzDwlJ4DOFZAAVgBaglNQUlOQ0xBU0NyCFZBVU5BME1FCioIuZYBEgQ3MDcxGMGTASCHBiiqmJ4DMNeYngM4VkABWAFqAkVScgNWSVAKmwEKKgi5lgESBDcwNjEYhwYgwZMBKJy6ngMwybqeAzhWQABYAWoCRVJyA1ZJUAo2CMSYARIEMTEyNxjBkwEgzHwokL2eAzDYvp4DOEtAAVgBaglNQUlOQ0xBU0NyCEtBVUdBME1RCjUIxJgBEgQ1MjUzGMx8IMNkKPO%5FngMwwcCeAzhLQAFYAWoJTUFJTkNMQVNDcghLQVVHQTBNURIMCAEQARgBKgJETDIAGAEiBAgBEAEoAigDKAQwAQ)

Wed, Nov 25 - Sun, Nov 29 · DSM · HYA · Roundtrip

[Select United flight, departing Wed, Nov 25 from Des Moines to Hyannis, returning Sun, Nov 29, priced at $1,360 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:HYA,departure:11/25/2026TANYT&leg2=from:HYA,to:DSM,departure:11/29/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1359.70&airProductToken=AQqXAQozCNWCARIENTMwOBjDZCCuHCi1jJ4DMJaNngM4VUAAWAFqB0VDT05PTVlyCFVBQTdBRkVOCjQI1YIBEgQxNjA2GK4cIMGTASi-jp4DMM-PngM4VUABWAFqB0VDT05PTVlyCFVBQTdBRkVOCioIuZYBEgQ3MDMxGMGTASCHBiiVkJ4DMMKQngM4QkABWAFqAkVScgNCSVAKlgEKKgi5lgESBDcxMDEYhwYgwZMBKP66ngMwsLueAzhCQABYAWoCRVJyA0JJUAozCNWCARIDNTYzGMGTASCuHCiEvp4DMLy%5FngM4VUABWAFqB0VDT05PTVlyCFVBQTBBS0VOCjMI1YIBEgQxODM5GK4cIMNkKJHAngMw68CeAzhVQAFYAWoHRUNPTk9NWXIIVUFBMEFLRU4SDAgBEAEYASoCVUEyABgBIgQIARABKAIoAygEMAE)

Wed, Nov 25 - Sun, Nov 29 · DSM · HYA · Roundtrip

## Book with confidence

### Des Moines to Hyannis Flights

#### The cheapest times to fly from Des Moines to Hyannis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Hyannis are during the month of November. You can find some of the cheapest flights from Des Moines to Hyannis with Expedia's search tool and vast selection of airlines.

#### The best time to book a flight from Des Moines to Hyannis

Sunday is one of the best days to book for cheap flights from Des Moines to Hyannis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

#### How to find cheap round-trip tickets from Des Moines to Hyannis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Hyannis in 2026\. You can also book with separate airlines for your outbound and return journeys, from $473 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference\*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Hyannis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's [vacation packages](https://www.expedia.com/package-deals). Bundling together your Des Moines to Hyannis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*\*Terms apply.*

*Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023\. The percentages you see are averages.*

## Frequently Asked Questions

### How much does a flight from Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal) cost?

You can find cheap one-way flights from $473 and cheap return flights $1,141 Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal) with Expedia. Roundtrip flights usually range from $1102 to $2348\. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal) ticket fares go up or down.

*\*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.*

### What is the cheapest month to fly from Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal)?

The cheapest month to fly from DSM to HYA is November when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.

### Which airlines fly direct from Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal)?

Enter DSM to HYA and your travel dates, then apply the 'Nonstop' filter to see only direct flights.

### What is the cheapest airline that flies from Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal)?

American Airlines is one of the cheapest airlines offering connecting flights from Des Moines, IA (DSM) to Hyannis, MA (HYA), with round-trip tickets starting from around $1,035\. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.

*\*Prices based on flights available on Expedia in the last year.*

### How do I find cheap flights from Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal)?

To find a cheap flight from Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up [Price Tracking](https://www.expedia.com/why/price-tracking) and receive alerts when fares go up or down.

### What is the best time to fly from Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal)?

The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.

### What is the earliest flight from Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal)?

The earliest flight from Des Moines International Airport (DSM) to Barnstable Municipal Airport (HYA) in Hyannis typically departs at around 5:40 AM. This service is operated by Delta and 9K. An early flight can give you a head start on your day in Hyannis. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.

### What day of the week has the most flights from Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal)?

The busiest day for flights from Des Moines Intl. (DSM) to Barnstable Municipal (HYA) is a Saturday, with around 11 flights. This gives you plenty of options for your travel plans. Major airlines on this route include American Airlines, Delta, and United.

### What are the most popular departure times for flights from Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal)?

The most popular departure times for flights from Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal) are in the early morning, from 6am to 9am. About 57% of passengers prefer this time window. Many major carriers, including United Airlines and American Airlines, offer flights during this window. This timing works well because it allows you to start your day early and enjoy your time in Hyannis.

### How long does it take to fly from Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal)?

Flights from DSM to HYA with one stop typically take around 12 hours, covering approximately 1,203 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.

### Can you fly business or first class from Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal)?

First class seats are offered on the DSM to HYA route with American Airlines.

### How do I earn miles on a Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal) flight with Expedia?

It's easy to earn miles on a Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of [One Key™](https://www.expedia.com/welcome-one-key), you can also earn OneKeyCash™\* on top of your airline miles when you book with Expedia.

\*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

### What airports do you fly into for Hyannis from Des Moines Intl. (DSM)?

From Des Moines Intl. (DSM), you can fly into Barnstable Municipal (HYA) to reach Hyannis. Some flights may connect through major hubs like O'Hare Intl. (ORD), LaGuardia (LGA), Denver Intl. (DEN) before reaching Hyannis. Compare routes and airports on Expedia to find the best flight options for your travel plans.

### Is it cheaper to buy a plane ticket from Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal) at the last minute?

Typically, booking a last minute flight from Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.

### Is it cheaper to book a Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal) flight and hotel package?

Securing a Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.

### Can I cancel or change the date of my flight from Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal)?

If you booked your Des Moines, IA (DSM-Des Moines Intl.) to Hyannis, MA (HYA-Barnstable Municipal) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in [your itinerary](https://www.expedia.com/trips) or confirmation email. Or, head to our [Customer Service portal](https://www.expedia.com/helpcenter/) if you'd like more information.

## Travel information

| Origin airport      | Des Moines International Airport |
| ------------------- | -------------------------------- |
| Destination airport | Hyannis, MA                      |
| Distance            | 1,203 miles away                 |
| Roundtrip price     | $1,141                           |

## Explore a world of travel with Expedia

- [Flights](?equalTargetTab=tab-0)
- [Flights from Norwood (OWD) to Hyannis (HYA)](https://www.expedia.com/lp/flights/owd/hya/norwood-to-hyannis)
- [Flights from Norfolk (ORF) to Hyannis (HYA)](https://www.expedia.com/lp/flights/orf/hya/norfolk-to-hyannis)
- [Flights from Kansas City (MCI) to Hyannis (HYA)](https://www.expedia.com/lp/flights/mci/hya/kansas-city-to-hyannis)
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- [Flights from New Bedford (EWB) to Hyannis (HYA)](https://www.expedia.com/lp/flights/ewb/hya/new-bedford-to-hyannis)
- [Flights from Wilmington (ILM) to Hyannis (HYA)](https://www.expedia.com/lp/flights/ilm/hya/wilmington-to-hyannis)
- [Flights from Charlottesville (CHO) to Hyannis (HYA)](https://www.expedia.com/lp/flights/cho/hya/charlottesville-to-hyannis)
- [Flights from Dallas (DFW) to Hyannis (HYA)](https://www.expedia.com/lp/flights/dfw/hya/dallas-to-hyannis)
- [Flights from Louisville (SDF) to Hyannis (HYA)](https://www.expedia.com/lp/flights/sdf/hya/louisville-to-hyannis)
- [Flights from Orlando (MCO) to Hyannis (HYA)](https://www.expedia.com/lp/flights/mco/hya/orlando-to-hyannis)
- [Flights from Worcester (ORH) to Hyannis (HYA)](https://www.expedia.com/lp/flights/orh/hya/worcester-to-hyannis)
- [Flights from San Diego (SAN) to Hyannis (HYA)](https://www.expedia.com/lp/flights/san/hya/san-diego-to-hyannis)
- [Flights from Harrisburg (MDT) to Hyannis (HYA)](https://www.expedia.com/lp/flights/mdt/hya/harrisburg-to-hyannis)
- [Flights from Richmond (RIC) to Hyannis (HYA)](https://www.expedia.com/lp/flights/ric/hya/richmond-to-hyannis)
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- [Flights from White Plains (HPN) to Hyannis (HYA)](https://www.expedia.com/lp/flights/hpn/hya/white-plains-to-hyannis)
- [Flights from New London (GON) to Hyannis (HYA)](https://www.expedia.com/lp/flights/gon/hya/new-london-to-hyannis)
- [Flights from Atlantic City (ACY) to Hyannis (HYA)](https://www.expedia.com/lp/flights/acy/hya/atlantic-city-to-hyannis)
- [Flights from Nantucket (ACK) to Hyannis (HYA)](https://www.expedia.com/lp/flights/ack/hya/nantucket-to-hyannis)
- [Flights from Phoenix (PHX) to Hyannis (HYA)](https://www.expedia.com/lp/flights/phx/hya/phoenix-to-hyannis)
- [Flights from Sarasota (SRQ) to Hyannis (HYA)](https://www.expedia.com/lp/flights/srq/hya/sarasota-to-hyannis)
- [Flights from Morristown (MMU) to Hyannis (HYA)](https://www.expedia.com/lp/flights/mmu/hya/morristown-to-hyannis)
- [Flights from St. Louis (STL) to Hyannis (HYA)](https://www.expedia.com/lp/flights/stl/hya/st-louis-to-hyannis)
- [Flights from Hartford (BDL) to Hyannis (HYA)](https://www.expedia.com/lp/flights/bdl/hya/hartford-to-hyannis)
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- [Flights from Teterboro (TEB) to Hyannis (HYA)](https://www.expedia.com/lp/flights/teb/hya/teterboro-to-hyannis)
- [Flights from Chicago (ORD) to Hyannis (HYA)](https://www.expedia.com/lp/flights/ord/hya/chicago-to-hyannis)
- [Flights from Charleston (CHS) to Hyannis (HYA)](https://www.expedia.com/lp/flights/chs/hya/charleston-to-hyannis)
- [Flights from Washington (IAD) to Hyannis (HYA)](https://www.expedia.com/lp/flights/iad/hya/washington-to-hyannis)
- [Flights from Portland (PWM) to Hyannis (HYA)](https://www.expedia.com/lp/flights/pwm/hya/portland-to-hyannis)
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- [Flights from Savannah (SAV) to Hyannis (HYA)](https://www.expedia.com/lp/flights/sav/hya/savannah-to-hyannis)
- [Flights from Denver (DEN) to Hyannis (HYA)](https://www.expedia.com/lp/flights/den/hya/denver-to-hyannis)
- [Flights from Tampa (TPA) to Hyannis (HYA)](https://www.expedia.com/lp/flights/tpa/hya/tampa-to-hyannis)
- [Flights from Cincinnati (CVG) to Hyannis (HYA)](https://www.expedia.com/lp/flights/cvg/hya/cincinnati-to-hyannis)
- [Flights from Syracuse (SYR) to Hyannis (HYA)](https://www.expedia.com/lp/flights/syr/hya/syracuse-to-hyannis)
- [Flights from Memphis (MEM) to Hyannis (HYA)](https://www.expedia.com/lp/flights/mem/hya/memphis-to-hyannis)
- [Flights from Palm Springs (PSP) to Hyannis (HYA)](https://www.expedia.com/lp/flights/psp/hya/palm-springs-to-hyannis)
- [Flights from Danbury (DXR) to Hyannis (HYA)](https://www.expedia.com/lp/flights/dxr/hya/danbury-to-hyannis)
- [Flights from West Palm Beach (PBI) to Hyannis (HYA)](https://www.expedia.com/lp/flights/pbi/hya/west-palm-beach-to-hyannis)
- [Flights from Newark Liberty Intl. Airport (EWR) to Hyannis (HYA)](https://www.expedia.com/lp/flights/ewr/hya/newark-liberty-intl-airport-to-hyannis)
- [Flights from Baltimore (BWI) to Hyannis (HYA)](https://www.expedia.com/lp/flights/bwi/hya/baltimore-to-hyannis)
- [Flights from Manchester (MHT) to Hyannis (HYA)](https://www.expedia.com/lp/flights/mht/hya/manchester-to-hyannis)
- [Flights from Washington (DCA) to Hyannis (HYA)](https://www.expedia.com/lp/flights/dca/hya/washington-to-hyannis)
- [Flights from Lancaster (LNS) to Hyannis (HYA)](https://www.expedia.com/lp/flights/lns/hya/lancaster-to-hyannis)
- [Flights from New York (LGA) to Hyannis (HYA)](https://www.expedia.com/lp/flights/lga/hya/new-york-to-hyannis)
- [Flights from Vero Beach (VRB) to Hyannis (HYA)](https://www.expedia.com/lp/flights/vrb/hya/vero-beach-to-hyannis)
- [Flights from Burlington (BTV) to Hyannis (HYA)](https://www.expedia.com/lp/flights/btv/hya/burlington-to-hyannis)
- [Flights from San Francisco (SFO) to Hyannis (HYA)](https://www.expedia.com/lp/flights/sfo/hya/san-francisco-to-hyannis)
- [Flights from Boston (BOS) to Hyannis (HYA)](https://www.expedia.com/lp/flights/bos/hya/boston-to-hyannis)
- [Flights from Philadelphia (PHL) to Hyannis (HYA)](https://www.expedia.com/lp/flights/phl/hya/philadelphia-to-hyannis)
- [Flights from Asheville (AVL) to Hyannis (HYA)](https://www.expedia.com/lp/flights/avl/hya/asheville-to-hyannis)
- [Flights from New York (LGA) to Nantucket (ACK)](https://www.expedia.com/lp/flights/lga/ack/new-york-to-nantucket)
- [Flights from Charlotte (CLT) to Hyannis (HYA)](https://www.expedia.com/lp/flights/clt/hya/charlotte-to-hyannis)
- [Flights from Miami (MIA) to Hyannis (HYA)](https://www.expedia.com/lp/flights/mia/hya/miami-to-hyannis)
- [Flights from Los Angeles (LAX) to Hyannis (HYA)](https://www.expedia.com/lp/flights/lax/hya/los-angeles-to-hyannis)
- [Flights from San Juan (SJU) to Hyannis (HYA)](https://www.expedia.com/lp/flights/sju/hya/san-juan-to-hyannis)
- [Flights from Providence (PVD) to Hyannis (HYA)](https://www.expedia.com/lp/flights/pvd/hya/providence-to-hyannis)
- [Flights from Raleigh (RDU) to Hyannis (HYA)](https://www.expedia.com/lp/flights/rdu/hya/raleigh-to-hyannis)
- [Flights from Cleveland (CLE) to Hyannis (HYA)](https://www.expedia.com/lp/flights/cle/hya/cleveland-to-hyannis)
- [Flights from Salt Lake City (SLC) to Hyannis (HYA)](https://www.expedia.com/lp/flights/slc/hya/salt-lake-city-to-hyannis)
- [Flights from Indianapolis (IND) to Hyannis (HYA)](https://www.expedia.com/lp/flights/ind/hya/indianapolis-to-hyannis)
- [Flights from Allentown (ABE) to Hyannis (HYA)](https://www.expedia.com/lp/flights/abe/hya/allentown-to-hyannis)
- [Flights from Portsmouth (PSM) to Hyannis (HYA)](https://www.expedia.com/lp/flights/psm/hya/portsmouth-to-hyannis)
- [Flights from Westfield (BAF) to Hyannis (HYA)](https://www.expedia.com/lp/flights/baf/hya/westfield-to-hyannis)
- [Flights from Albany (ALB) to Hyannis (HYA)](https://www.expedia.com/lp/flights/alb/hya/albany-to-hyannis)
- [Flights from Myrtle Beach (MYR) to Hyannis (HYA)](https://www.expedia.com/lp/flights/myr/hya/myrtle-beach-to-hyannis)
- [Flights from Fort Lauderdale (FLL) to Hyannis (HYA)](https://www.expedia.com/lp/flights/fll/hya/fort-lauderdale-to-hyannis)
- [Flights from Pittsburgh (PIT) to Hyannis (HYA)](https://www.expedia.com/lp/flights/pit/hya/pittsburgh-to-hyannis)
- [Flights from St. Petersburg (PIE) to Hyannis (HYA)](https://www.expedia.com/lp/flights/pie/hya/st-petersburg-to-hyannis)
- [Flights from Wilkes-Barre (AVP) to Hyannis (HYA)](https://www.expedia.com/lp/flights/avp/hya/wilkes-barre-to-hyannis)
- [Flights from Rochester (ROC) to Hyannis (HYA)](https://www.expedia.com/lp/flights/roc/hya/rochester-to-hyannis)
- [Flights from Newburgh (SWF) to Hyannis (HYA)](https://www.expedia.com/lp/flights/swf/hya/newburgh-to-hyannis)
- [Flights from Bangor (BGR) to Hyannis (HYA)](https://www.expedia.com/lp/flights/bgr/hya/bangor-to-hyannis)
- [Flights from New York (NYC) to Hyannis (HYA)](https://www.expedia.com/lp/flights/nyc/hya/new-york-to-hyannis)
- [Flights from Knoxville (TYS) to Hyannis (HYA)](https://www.expedia.com/lp/flights/tys/hya/knoxville-to-hyannis)
- [Flights from Montreal (YUL) to Hyannis (HYA)](https://www.expedia.com/lp/flights/yul/hya/montreal-to-hyannis)
- [Flights from Greenville (GSP) to Hyannis (HYA)](https://www.expedia.com/lp/flights/gsp/hya/greenville-to-hyannis)
- [Flights from Buffalo (BUF) to Hyannis (HYA)](https://www.expedia.com/lp/flights/buf/hya/buffalo-to-hyannis)
- [Flights from Aspen (ASE) to Hyannis (HYA)](https://www.expedia.com/lp/flights/ase/hya/aspen-to-hyannis)
- [Flights from Las Vegas (LAS) to Hyannis (HYA)](https://www.expedia.com/lp/flights/las/hya/las-vegas-to-hyannis)
- [Flights from Trenton (TTN) to Hyannis (HYA)](https://www.expedia.com/lp/flights/ttn/hya/trenton-to-hyannis)
- [Flights from Chattanooga (CHA) to Hyannis (HYA)](https://www.expedia.com/lp/flights/cha/hya/chattanooga-to-hyannis)
- [Flights from Austin (AUS) to Hyannis (HYA)](https://www.expedia.com/lp/flights/aus/hya/austin-to-hyannis)
- [Flights from Ithaca (ITH) to Hyannis (HYA)](https://www.expedia.com/lp/flights/ith/hya/ithaca-to-hyannis)
- [Flights from New Haven (HVN) to Hyannis (HYA)](https://www.expedia.com/lp/flights/hvn/hya/new-haven-to-hyannis)
- [Flights from Seattle (SEA) to Hyannis (HYA)](https://www.expedia.com/lp/flights/sea/hya/seattle-to-hyannis)
- [Flights from Toronto (YYZ) to Hyannis (HYA)](https://www.expedia.com/lp/flights/yyz/hya/toronto-to-hyannis)
- [Flights from Atlanta (ATL) to Hyannis (HYA)](https://www.expedia.com/lp/flights/atl/hya/atlanta-to-hyannis)
- [Flights from Fort Myers (RSW) to Hyannis (HYA)](https://www.expedia.com/lp/flights/rsw/hya/fort-myers-to-hyannis)
- [Flights from New York (JFK) to Hyannis (HYA)](https://www.expedia.com/lp/flights/jfk/hya/new-york-to-hyannis)
- [Flights from Madison (MSN) to Hyannis (HYA)](https://www.expedia.com/lp/flights/msn/hya/madison-to-hyannis)
- [Flights from Jacksonville (JAX) to Hyannis (HYA)](https://www.expedia.com/lp/flights/jax/hya/jacksonville-to-hyannis)
- [Flights from Islip (ISP) to Hyannis (HYA)](https://www.expedia.com/lp/flights/isp/hya/islip-to-hyannis)
- [Flights from New York (JFK) to Vineyard Haven (MVY)](https://www.expedia.com/lp/flights/jfk/mvy/new-york-to-vineyard-haven)
- [Flights from Detroit (DTW) to Hyannis (HYA)](https://www.expedia.com/lp/flights/dtw/hya/detroit-to-hyannis)
- [Flights from Milwaukee (MKE) to Hyannis (HYA)](https://www.expedia.com/lp/flights/mke/hya/milwaukee-to-hyannis)
- [Flights from Nashville (BNA) to Hyannis (HYA)](https://www.expedia.com/lp/flights/bna/hya/nashville-to-hyannis)

\*Available to One Key members.

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