Plan your trip

Find 5 Star Hotels in Isone from $84

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices

    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

  • Check prices for these dates

    Check prices for these dates, December 14 – 15, 2026

    View in a map

    Our top choices for Isone 5-star hotels

    1. Grand Hotel Tremezzo

    A resort with a pool, sun loungers, and a mountain backdrop.

    2. Grand Hotel Villa Serbelloni

    A room with a sofa, a coffee table, a decorative sculpture, a painting, and a window with a view of greenery.

    3. Swiss Diamond Boutique Hotel La Romantica

    A modern building with a water feature in front.

    4. The Lake Como EDITION

    A pool area with lounge chairs and umbrellas, surrounded by mountains and a body of water.

    5. Grand Hotel Victoria Concept & Spa, by R Collection Hotels

    A pool area with lounge chairs and a view of a lake and mountains.

    6. Passalacqua

    A lakeside resort with outdoor seating areas, a gazebo, and a view of the lake and surrounding mountains.

    7. Swiss Diamond Hotel & SPA

    A waterfront hotel with multiple balconies, a marina, and a view of the lake.

    8. Hotel Splendide Royal

    A luxurious dining area with elegant decor, a view of a lake, and mountains in the background.

    9. ARIA Retreat & SPA - The Leading Hotels of the World

    A terrace with a view of a lake and mountains, featuring a sofa, a table, and a lounge chair.

    10. Villa Principe Leopoldo

    A large, two-story building with a symmetrical facade, a central entrance, and a circular driveway leading to a landscaped garden.

    11. Grand Hotel Villa Castagnola

    A table with a bottle of champagne, two glasses, and a dessert tray with strawberries and leaves, set against a scenic mountain view.

    12. Collina d'Oro Resort & SPA

    A swimming pool with lounge chairs and umbrellas, surrounded by mountains.

    13. Grand Hotel Campione

    A modern bathroom with a freestanding bathtub, a vanity with a mirror, and a view of a mountain and water body.

    14. Giardino Ascona

    A resort with outdoor seating, a pool, and mountain views.

    15. Villa Lario Resort Mandello

    A room with a large arched window offering a view of a lake, mountains, and a distant cityscape.

    16. MUSA Lago Di Como

    A balcony with wicker chairs, a small round table with a tray of items, and a view of a lake with mountains in the background.

    17. Hotel Eden Roc

    A swimming pool with a view of a lake and mountains.

    18. Castello del Sole Beach Resort & SPA

    A clear swimming pool with a metal ladder, surrounded by lush greenery and a white umbrella.

    19. The View Lugano

    A person in a swimming pool with a view of a cityscape and mountains.

    20. Swiss Hotel Apartments - Lugano

    A modern kitchen with built-in appliances, a dining area with a table and chairs, and a vase with red flowers.

    Top Isone Hotel Reviews

    Swiss Diamond Boutique Hotel La Romantica

    A modern building with a water feature in front.

    La Locanda del Cantiere

    A table set for dining with a scenic mountain and lake view.

    Grand Hotel Villa Castagnola

    A table with a bottle of champagne, two glasses, and a dessert tray with strawberries and leaves, set against a scenic mountain view.

    Al Molo 5

    A table with a bottle of champagne, two wine glasses, and a bowl of strawberries on a balcony overlooking a lake with mountains in the background.

    Hotel Splendide Royal

    A luxurious dining area with elegant decor, a view of a lake, and mountains in the background.

    Collina d'Oro Resort & SPA

    A swimming pool with lounge chairs and umbrellas, surrounded by mountains.

    The View Lugano

    A person in a swimming pool with a view of a cityscape and mountains.

    Lago Dorato Marina Lodge - Lakefront

    A boat with a bottle of champagne, two wine glasses, a straw hat, and a small Italian flag on the deck.

    Villa Principe Leopoldo

    A large, two-story building with a symmetrical facade, a central entrance, and a circular driveway leading to a landscaped garden.

    Relais Villa Vittoria

    A pool area with a view of a lake and mountains.

    MUSA Lago Di Como

    A balcony with wicker chairs, a small round table with a tray of items, and a view of a lake with mountains in the background.

    Grand Hotel Campione

    A modern bathroom with a freestanding bathtub, a vanity with a mirror, and a view of a mountain and water body.

    Swiss Diamond Hotel & SPA

    A waterfront hotel with multiple balconies, a marina, and a view of the lake.

    Passalacqua

    A lakeside resort with outdoor seating areas, a gazebo, and a view of the lake and surrounding mountains.

    Find out more about Isone

    Isone Five Star Hotel Information

    If you’re searching for the celebrity treatment, the 5 star hotels in Isone are your dreams come true. From sprawling resorts to fancy hot spots, theseIsone 5 star hotels immerse each traveler in the most elite experience money can buy. Want to unwind with a VIP-worthy spa treatment? These hotels have the leisure you're looking for.

    Interested in sampling world-class cuisine? The on-site restaurants at the 5 stars hotels in Isone, Canton of Ticino, let you do just that. You’ll even be able to book a room (or perhaps a penthouse?) at first-rate hotels near the region’s can’t-miss sights and most bustling shopping centers. Plus, many globe-trotters who visit Isone five star hotels find incredible rates and deep discounts thanks to Expedia, so you can score a deal without sacrificing an ounce of quality.

    Everything you could possibly want (and a few things you didn’t know you needed): That’s what you’ll receive when you stay at Isone 5 star hotels.

    Frequently Asked Questions

    What are the best 5-star hotels in Isone?

    Boasting superior amenities and guest services, our customers rate Grand Hotel Villa Castagnola as among the top 5-star hotels in Isone. You'll be immersed in a world of luxury from the second you enter the lobby.

    How much does it cost to stay in a 5-star hotel in Isone?

    The amount you pay for a 5-star hotel in Isone can vary based on when you prefer to travel and how long you plan to stay, among a number of factors. Use our price per night filter and other search tools to land the best rate on a high-end getaway.

    What makes a hotel 5 stars in Isone?

    In Isone, a hotel must offer a certain level of high-end conveniences to be designated 5 stars. These may include on-site gyms, spas and saunas, gourmet restaurants, luxury toiletries, premium bedding and more. What also sets 5-star hotels apart is their superior standard of service. You can look forward to things like concierge services, nightly turn-down services and in-room massage. Some may also offer extra touches such as welcome gifts.

    Are there any 5-star all-inclusive resorts in Isone?

    Find an upscale retreat that includes your room, meals, drinks and entertainment in Isone with our handy filters. Search for resorts rated 5 stars and select the "All inclusive" filter. Double-check what's included in the upfront price. This way, you'll be ready to maximize all the perks on offer when you get there.

    What are the top 5-star spa hotels in Isone?

    For a rejuvenating break in Isone, you can't beat Grand Hotel Villa Castagnola. Book a room at this 5-star spa property and relax while spoiling yourself with its wellness programs and therapies.

    Are there any 5-star vacation rentals in Isone?

    You won't find any 5-star vacation rentals in Isone on our site, but there are a range of other highly rated options worth looking into. Scan through our vacation rentals in Isone to book the ideal place for your getaway.

    What are the best 5-star apartments in Isone?

    Luxury and comfort are what you can look forward to at Barony Le Pergole, a 5-star option that ranks highly among Expedia travelers. With features like large interiors, modern kitchens and state-of-the-art entertainment systems, our high-end apartments in Isone deliver a VIP experience.

    Explore a world of travel with Expedia