Title: The Best 5 Star Hotels in San Luis, CO  | Expedia.com

[San Luis Travel Guide](https://expedia.com/San-Luis.dx3000429673)[Hotels in San Luis](https://expedia.com/San-Luis-Hotels.d3000429673.Travel-Guide-Hotels)[Vacation Rentals in San Luis](https://expedia.com/San-Luis-Vacation-Rentals.d3000429673.Travel-Guide-VacationRentals)[Flights to San Luis](https://expedia.com/Cheap-Flights-To-San-Luis.d3000429673.Travel-Guide-Flights)[Car Rentals in San Luis](https://expedia.com/Car-Rentals-In-San-Luis.d3000429673.Car-Rental-Guide)[San Luis Vacation Packages](https://expedia.com/San-Luis.d3000429673.Destination-Travel-Guides)

![Sangre de Cristo Mountains - Panoramic view of Snow-capped Sangre de Cristo Mountains, reflecting in San Luis Lake. Colorado, USA.](https://images.trvl-media.com/place/3000429673/a43f2791-0578-4753-a9ee-1d53181905aa.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on San Luis 5 Star Hotels

Tonight

[Feb 6 - Feb 7](https://www.expedia.com/Hotel-Search?regionId=3000429673&startDate=2026-02-06&endDate=2026-02-07&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 7 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=3000429673&startDate=2026-02-07&endDate=2026-02-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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[Feb 6 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=3000429673&startDate=2026-02-06&endDate=2026-02-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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[Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=3000429673&startDate=2026-02-13&endDate=2026-02-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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## Learn more about San Luis

Explore Colorado's oldest town where the adobe Sangre de Cristo Parish church anchors the historic plaza. Hike nearby trails in the San Luis Valley or time your visit for the town's vibrant cultural festivals celebrating Hispanic heritage.

[See all hotels in San Luis](https://www.expedia.com/Hotel-Search?startDate=2026-02-20&endDate=2026-02-21&adults=2&regionId=3000429673)

![Sangre de Cristo Mountains - Panoramic view of Snow-capped Sangre de Cristo Mountains, reflecting in San Luis Lake. Colorado, USA.](https://images.trvl-media.com/place/3000429673/a43f2791-0578-4753-a9ee-1d53181905aa.jpg?impolicy=fcrop&w=900&h=299&p=1&q=high)

## Top San Luis Hotel Reviews

## Find out more about San Luis

## San Luis Five Star Hotel Information

If you’re searching for the celebrity treatment, the 5 star hotels in San Luis are your dreams come true. From sprawling resorts to fancy hot spots, theseSan Luis 5 star hotels immerse each traveler in the most elite experience money can buy. Want to unwind with a VIP-worthy spa treatment? These hotels have the leisure you're looking for.

Interested in sampling world-class cuisine? The on-site restaurants at the 5 stars hotels in San Luis, Colorado, let you do just that. You’ll even be able to book a room (or perhaps a penthouse?) at first-rate hotels near the region’s can’t-miss sights and most bustling shopping centers. Plus, many globe-trotters who visit San Luis five star hotels find incredible rates and deep discounts thanks to Expedia, so you can score a deal without sacrificing an ounce of quality.

Everything you could possibly want (and a few things you didn’t know you needed): That’s what you’ll receive when you stay at San Luis 5 star hotels.

## Frequently asked questions

### How much does it cost to stay in a 5-star hotel in San Luis?

> - Search for the lowest price per night

### What makes a hotel 5 stars in San Luis?

### Are there any 5-star all-inclusive resorts in San Luis?

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