Irene Vacations from $190

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The Latest Irene vacation packages

Price found within the past 48 hours. Click for updated prices.
Valley Inn

Valley Inn

2.5 out of 5
Price was $227, price is now $190 per person
$190
per person
Nov 14 - Nov 16
found 24 hours ago
Roundtrip flight included
Denver (DEN) to Sioux Falls (FSD)
7.6/10 Good! (1,002 reviews)
It is close to the Sanford Hospital complex so elderly do not have to dive far.

Reviewed on Sep 20, 2025

Historic Twin Tudors Inn

Historic Twin Tudors Inn

3 out of 5
Price was $323, price is now $243 per person
$243
per person
Nov 14 - Nov 16
found 24 hours ago
Roundtrip flight included
Denver (DEN) to Sioux Falls (FSD)
8.8/10 Excellent! (3 reviews)
We were upgraded to staying at the Victorian Inn- i would highly recommended. The house is charming and located in the historic downtown of Sioux Falls.

Reviewed on Jun 16, 2025

Hotel On Phillips

Hotel On Phillips

2.5 out of 5
Downtown Sioux Falls
Price was $412, price is now $321 per person
$321
per person
Nov 14 - Nov 16
found 24 hours ago
Roundtrip flight included
Denver (DEN) to Sioux Falls (FSD)
9.6/10 Exceptional! (1,190 reviews)
Friendly and helpful staff. Very comfortable

Reviewed on Sep 29, 2025

Clubhouse Hotel Suites Sioux Falls

Clubhouse Hotel Suites Sioux Falls

3 out of 5
Price was $355, price is now $290 per person
$290
per person
Nov 14 - Nov 16
found 24 hours ago
Roundtrip flight included
Denver (DEN) to Sioux Falls (FSD)
9.6/10 Exceptional! (1,012 reviews)
Very nice hotel my only complaint is it is difficult to cal the hotel directly as all the numbers are for corporate or a computer

Reviewed on Sep 27, 2025

Hilton Garden Inn Sioux Falls South

Hilton Garden Inn Sioux Falls South

3 out of 5
Price was $276, price is now $227 per person
$227
per person
Nov 14 - Nov 16
found 24 hours ago
Roundtrip flight included
Denver (DEN) to Sioux Falls (FSD)
8.8/10 Excellent! (686 reviews)
The heat doesn't work

Reviewed on Sep 28, 2025

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Irene Hotel Deals

Yankton Inn

Yankton Inn

2 out of 5
1603 East Highway 50, Yankton, SD
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $94 total per night from Sep 30 to Oct 1
$94 total
Sep 30 - Oct 1
Total with taxes and fees
7.4/10 Good! (255 reviews)
"It is an older building hallways do not have air conditioning in hallways, bed was comfortable, nice breakfasts with protein's."

Reviewed on Sep 23, 2025

Yankton Inn
Comfort Inn Yankton SD

Comfort Inn Yankton SD

2.5 out of 5
611 W 23rd Street, Yankton, SD
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $112 total per night from Oct 7 to Oct 8
$112 total
Oct 7 - Oct 8
Total with taxes and fees
8.8/10 Excellent! (627 reviews)
"It was nicr"

Reviewed on Sep 23, 2025

Comfort Inn Yankton SD
Lewis and Clark Resort

Lewis and Clark Resort

2.5 out of 5
43496 Shore Drive, Yankton, SD
$98 nightly
The price is $104 total per night from Oct 30 to Oct 31
$104 total
Oct 30 - Oct 31
Total with taxes and fees
8.6/10 Excellent! (257 reviews)
"Enjoyed outdoor"

Reviewed on Sep 13, 2025

Lewis and Clark Resort
See all 80 properties in Irene
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does an Irene vacation package cost?
You can grab a vacation package to this destination from $190 on Expedia. But how much your vacation to Irene costs will depend on factors like the length of stay, hotel choice and season.
What are the cheapest months to go to Irene?
You can typically find reduced prices and better availability in February, November and December. Explore our cheap Irene vacation packages and you could land some great off-season deals.
How many days is enough for Irene?
The ideal length for your Irene vacation depends on what you'd like to see. Generally, a few days to a week will give you enough time to hit all the major attractions and discover some hidden gems along the way.
How to find the best Irene package deals?
Landing a cheap Irene package deal is a breeze with Expedia. After you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, add some filters and see what's available. You can customize your search by "Amenities," "Property type," "Traveler experience" and more. Sort the results by "Price: low to high" to discover the most wallet-friendly Irene package deals. Want a simple trick to get the biggest savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are generally lower.
Is it cheaper to book an Irene vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your flight, hotel and car rental into one great-value price and enjoy significant savings. You'll generally get a better deal than booking each component individually. And you'll still get the flexibility to create a tailored Irene vacation by choosing your preferred type of stay, airline and car class.
When to book a vacation package to Irene?
If you have your Irene vacation dates confirmed, book early to snap up some outstanding deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spur-of-the-moment trips? Our last-minute deals are great for jetting off on a whim.
Does Expedia offer Book Now, Pay Later Irene vacation packages?
If you're like us, you love discovering new places but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With help from online lender Affirm, you can break down the overall cost of your Irene trip over 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can secure cheap vacation packages with payment plans as soon as you see them.

Explore a world of travel with Expedia

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.