Irene Vacations from $453

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The Latest Irene vacation packages

Price found within the past 48 hours. Click for updated prices.
Country Inn & Suites by Radisson, Sioux Falls, SD
Canopy By Hilton Sioux Falls Downtown
AeroStay Hotel
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
Clubhouse Hotel Suites Sioux Falls
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Irene Hotel Deals

Comfort Inn Yankton SD

Comfort Inn Yankton SD

2.5 out of 5
611 W 23rd Street Yankton SD
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $100 total per night from Dec 4 to Dec 5
$100 total
Dec 4 - Dec 5
Total with taxes and fees
8.8/10 Excellent! (653 reviews)
.

Reviewed on Nov 13, 2025

Comfort Inn Yankton SD
Best Western Kelly Inn

Best Western Kelly Inn

2.5 out of 5
1607 E Highway 50, Yankton, SD
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $109 total per night from Nov 23 to Nov 24
$109 total
Nov 23 - Nov 24
Total with taxes and fees
8/10 Very Good! (644 reviews)
This was the perfect hotel for my family to stay in for a wedding. We enjoyed the breakfast, pool, and attached restaurant. I would stay there again.

Reviewed on Oct 13, 2025

Best Western Kelly Inn
Lewis and Clark Resort

Lewis and Clark Resort

2.5 out of 5
43496 Shore Drive, Yankton, SD
$89 nightly
The price is $94 total per night from Dec 1 to Dec 2
$94 total
Dec 1 - Dec 2
Total with taxes and fees
8.6/10 Excellent! (278 reviews)
Front desk was very personable. The cabin was roomy and comfortable.

Reviewed on Nov 11, 2025

Lewis and Clark Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Irene Essential Information

Language
English
Currency
U.S dollars
Population
420

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Frequently asked questions

How much does an Irene vacation package cost?
You can grab a vacation package to this destination from $453 on Expedia. But how much your vacation to Irene costs will depend on factors like the length of stay, hotel choice and season.
What are the cheapest months to go to Irene?
You can typically find reduced prices and better availability in February, November and December. Explore our cheap Irene vacation packages and you could land some great off-season deals.
How many days is enough for Irene?
The ideal length for your Irene vacation depends on what you'd like to see. Generally, a few days to a week will give you enough time to hit all the major attractions and discover some hidden gems along the way.
How to find the best Irene package deals?
Landing a cheap Irene package deal is a breeze with Expedia. After you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, add some filters and see what's available. You can customize your search by "Amenities," "Property type," "Traveler experience" and more. Sort the results by "Price: low to high" to discover the most wallet-friendly Irene package deals. Want a simple trick to get the biggest savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are generally lower.
Is it cheaper to book an Irene vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your flight, hotel and car rental into one great-value price and enjoy significant savings. You'll generally get a better deal than booking each component individually. And you'll still get the flexibility to create a tailored Irene vacation by choosing your preferred type of stay, airline and car class.
When to book a vacation package to Irene?
If you have your Irene vacation dates confirmed, book early to snap up some outstanding deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spur-of-the-moment trips? Our last-minute deals are great for jetting off on a whim.
Does Expedia offer Book Now, Pay Later Irene vacation packages?
If you're like us, you love discovering new places but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With help from online lender Affirm, you can break down the overall cost of your Irene trip over 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can secure cheap vacation packages with payment plans as soon as you see them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.