1. Comfort Inn Yankton SD

- Location: Yankton
- Guest rating: 8.8/10 (Excellent, 804 reviews)
- Price: $95 nightly, $105 total, Dec 6 - Dec 7, Total with taxes and fees, for Our top choices for Irene 2-star hotels
- Review: I love this place!, by Virginia
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Check prices for these dates, December 13 – 14, 2026













Planning a getaway with only a few bucks to spare? Expedia can help! With the inexpensive rates at the top motels in Irene, South Dakota you can put together the vacation of your dreams without spending every penny of your yearly travel budget.
These smaller places are ideal if you need a home base that lets you easily explore the local sights; many of the best motels in Irene are located near major freeways and public transportation. Plus, when you book a cheap deal on a motel in Irene, you’ll find quiet rooms, complimentary toiletries, and comfortable sleeping areas, so you can unwind after a long day.
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Travelers can find great deals on Irene 2-star hotels from $76 with Expedia – but remember that prices vary throughout the year. Factors like demand and location can affect hotel prices, and it’s often more expensive to stay in Irene hotels during weekends, holidays and high season. Try searching for 2-star Irene hotels during midweek to track down the best deals.
With all the home comforts travelers need, 2-star Irene hotels make a great base for exploring. These hotels are designed for convenience, and usually have comfy rooms, daily housekeeping services, and a 24-hour front desk. Some also have their own restaurant. For travelers who want to take things up a gear, 3-star Irene hotels might tick all the boxes. These mid-range hotels often have spacious rooms and extra amenities for a relaxing stay, such as a pool, gym, restaurant or bar.