
Vermillion Vacations from $502
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Your Vermillion Vacation
When you lock in a vacation package to Vermillion, all the planning is done in advance. This gives you plenty of time to uncover some of the things that define this historic city, such as its small-town feel, laid-back lifestyle and welcoming locals. If your trip to Vermillion includes a little sightseeing, hit up popular attractions like University of South Dakota, DakotaDome and National Music Museum. Stop dreaming and start traveling. Browse the broad range of options on Expedia today and put your Vermillion vacation plans into gear!
The Latest Vermillion vacation packages


Historic Twin Tudors Inn
Reviewed on Jun 16, 2025



Hotel On Phillips
Reviewed on Aug 25, 2025
Discover the most popular places to visit in Vermillion

University of South Dakota
Explore the campus of University of South Dakota, during your trip to Vermillion. While in this family-friendly area, you can savor the bars and restaurants.
DakotaDome
Catch an event at DakotaDome during your trip to Vermillion. While in this family-friendly area, you can savor the bars and restaurants.
National Music Museum
You can spend time exploring the galleries in National Music Museum during your trip to Vermillion. While in this family-friendly area, you can savor the bars and restaurants.
Vermillion Hotel Deals

Holiday Inn Express Hotel & Suites Vermillion by IHG

Best Western Vermillion Inn

Red Roof Inn Vermillion - U of South Dakota
Reviewed on Aug 24, 2025