Sioux Empire Medical Museum Tours

Keep your curious mind busy and discover more about the world at Sioux Empire Medical Museum. Study the displays and discover the story behind every piece.

Sioux Empire Medical Museum is an ideal place to begin your day of discovery in Sioux Falls. This museum comes recommended by fellow travelers, but it isn't the only thing to do here. Save time for other sights like Denny Sanford Premier Center, Empire Mall, and Falls Park to fully experience what the area has to offer.

Plan a trip to see Sioux Empire Medical Museum

Price found within the past 48 hours. Click for updated prices.
Valley Inn

Valley Inn

2.5 out of 5
University Heights
Price was $370, price is now $339 per person
$339
per person
Dec 6 - Dec 8
found 1 day ago
Roundtrip non-stop flight included
Washington (WAS) to Sioux Falls (FSD)
7.6/10 Good! (1,004 reviews)
Clean room, place to stay next to the hospital.

Reviewed on Oct 26, 2025

Hotel On Phillips

Hotel On Phillips

2.5 out of 5
Downtown Sioux Falls
Price was $500, price is now $437 per person
$437
per person
Dec 6 - Dec 8
found 1 day ago
Roundtrip non-stop flight included
Washington (WAS) to Sioux Falls (FSD)
9.6/10 Exceptional! (1,238 reviews)
Sweet find. Great room, nice restaurant, eclectic decor, awesome parking, very walkable location

Reviewed on Oct 29, 2025

Historic Victorian Inn

Historic Victorian Inn

3 out of 5
Cathedral
Price was $460, price is now $419 per person
$419
per person
Dec 6 - Dec 8
found 1 day ago
Roundtrip non-stop flight included
Washington (WAS) to Sioux Falls (FSD)
8.8/10 Excellent! (56 reviews)
No staff present. Remote guy emailed us like 20 times. Unexpected fee of $300 deposit. I think that’s a bit excessive. So so many rules. I was literally afraid to touch anything. House is ready for serious restoration. Could be a really fabulous place. I wouldn’t stay there again.

Reviewed on Jul 11, 2025

Popular places to visit

Explore the fascinating life of South Dakota's first U.S. Senator R. F. Pettigrew, who was also an explorer and collector of artifacts and archaeology from across the globe. Beautiful Victorian home and a museum of his collections and contributions to the development of Sioux Falls.

Pettigrew Home and Museum

You can spend time browsing the exhibits at Pettigrew Home and Museum during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.

Pettigrew Home and Museum
Guests can feed the giraffes in the African exhibit at the Great Plains Zoo.

Great Plains Zoo

4.5/5(74 reviews)

Why not visit the native and exotic animals who live at Great Plains Zoo during your travels in Sioux Falls? Attend a sporting event or discover the area's beautiful waterfalls.

Great Plains Zoo
An interesting museum

Old Courthouse Museum

4.5/5(60 reviews)

You can spend time browsing the exhibits at Old Courthouse Museum in Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.

Old Courthouse Museum

Sanford USD Medical Center

4.5/5(84 reviews)

Though Sanford USD Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Sioux Falls while you are here.

Sanford USD Medical Center

University of Sioux Falls

4/5(73 reviews)

Take a campus tour or just explore the area of University of Sioux Falls, during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.

University of Sioux Falls

Edith Mortenson Theatre Center

You can get tickets for a performance at Edith Mortenson Theatre Center on your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.

Edith Mortenson Theatre Center

Best Lodging Options Near Sioux Empire Medical Museum

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

3 out of 5
1301 West Russell, I-29 and Exit 81, Sioux Falls, SD
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
Days Inn by Wyndham Sioux Falls Empire

Days Inn by Wyndham Sioux Falls Empire

2 out of 5
3401 Gateway Blvd, I-29 and 41st Street Exit 77, Sioux Falls, SD
Days Inn by Wyndham Sioux Falls Empire
Hotel On Phillips

Hotel On Phillips

2.5 out of 5
100 N Phillips Ave, Sioux Falls, SD
Hotel On Phillips
Clubhouse Hotel Suites Sioux Falls

Clubhouse Hotel Suites Sioux Falls

3 out of 5
2320 South Louise Avenue, Sioux Falls, SD
Clubhouse Hotel Suites Sioux Falls
Valley Inn

Valley Inn

2.5 out of 5
1000 S. Grange Ave, Sioux Falls, SD
Valley Inn
Country Inn & Suites by Radisson, Sioux Falls, SD

Country Inn & Suites by Radisson, Sioux Falls, SD

3 out of 5
200 E 8th St, Sioux Falls, SD
Country Inn & Suites by Radisson, Sioux Falls, SD
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

3 out of 5
1120 S Grange Ave, Sioux Falls, SD
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
Holiday Inn Sioux Falls-City Centre by IHG

Holiday Inn Sioux Falls-City Centre by IHG

3 out of 5
100 W 8th St, Sioux Falls, SD
Holiday Inn Sioux Falls-City Centre by IHG
Sleep Inn Airport

Sleep Inn Airport

2.5 out of 5
1500 N Kiwanis Ave, Sioux Falls, SD
Sleep Inn Airport
See all 391 properties in Sioux Empire Medical Museum
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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