The Best Hotels Closest to Lewis and Clark Interpretive Center in St. Louis for 2026

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Our top choices for Lewis and Clark Interpretive Center hotels

A lobby with a sofa, two armchairs, a coffee table, and a staircase.

A modern hotel room with a large window, a flat-screen TV mounted on the wall, a round dining table with chairs, and a patterned rug.

A park with a pathway, trees, and a modern sculpture.

A rooftop lounge with large windows, red seating, and a view of the cityscape.

1. Hyatt Regency St. Louis at The Arch

13 mi from Lewis and Clark Interpretive Center

David

$134 nightly

$158 total

Oct 2 - Oct 3

Total with taxes and fees

A hotel room with a large bathtub, a small table with two chairs, a minibar, and a large mirror.

A coffee station with Folgers coffee, a coffee machine, and a refrigerator.

A hotel lobby with a desk, computer, and seating area.

A lobby with red walls, a clock, seating area, and a reception desk.

2. Econo Lodge Inn & Suites Granite City - St. Louis

2.9 mi from Lewis and Clark Interpretive Center

Latasha

$68 nightly

$78 total

Oct 25 - Oct 26

Total with taxes and fees

A motel with two electric vehicle charging stations and a sign indicating it's a budget motel.

A compact room with a wooden desk, a black chair, a round wooden table, a black sofa, a flat-screen TV mounted on the wall, and a microwave on a black cabinet.

A hotel room with a bed, a desk, a lamp, and a chair.

A bathroom with a yellow wall, a white sink, a mirror, and a toilet.

3. Budget Motel Granite City/St Louis Area

2.9 mi from Lewis and Clark Interpretive Center

Pi-Ming

$70 nightly

$76 total

Sep 27 - Sep 28

Total with taxes and fees

The Clayton Plaza Hotel sign with a stone wall and plants in front.

A living room with a brown leather sofa, a small table, and a chair. There is a window with curtains, a lamp, and a framed picture on the wall.

A lobby with a chandelier, a round table with a floral arrangement, and a painting on the wall.

A hotel room with two beds, a desk, a chair, and a television.

4. Clayton Plaza Hotel & Extended Stay

16.5 mi from Lewis and Clark Interpretive Center

Sivakumar

$94 nightly

$110 total

Oct 11 - Oct 12

Total with taxes and fees

A rooftop terrace with wicker furniture, offering a city view.

A modern hotel lobby with a bar area, seating arrangements, and a large chandelier.

A lobby with seating areas, a chandelier, and a large pillar.

A spacious lobby with a blue sofa, a glass coffee table, and a chandelier.

5. Drury Plaza Hotel St. Louis at the Arch

13.1 mi from Lewis and Clark Interpretive Center

Salvatore

$135 nightly

$158 total

Oct 2 - Oct 3

Total with taxes and fees

A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

A modern bar area with a central fire feature, bar stools, and seating.

A restaurant with tables set for dining, a kitchen in the background, and hanging light fixtures.

A modern living room with a sofa, coffee table, and bookshelves.

6. Live by Loews - St.Louis

13.2 mi from Lewis and Clark Interpretive Center

Frank

$159 nightly

$189 total

Sep 27 - Sep 28

Total with taxes and fees

A bar area with a central bar, multiple stools, and a chandelier.

A grand lobby with a bar area, chandeliers, and seating.

A spacious lobby with a high ceiling, ornate chandeliers, and a seating area with sofas and armchairs.

A grand lobby with a large chandelier, a bar area, and classical architecture.

7. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

12.9 mi from Lewis and Clark Interpretive Center

Carol

$111 nightly

$132 total

Sep 27 - Sep 28

Total with taxes and fees

A rooftop restaurant with round tables, chairs, and a view of the city.

A modern lobby with a staircase, seating area, and wall-mounted artwork.

A modern lobby with a staircase, seating area, and an exit sign.

A hotel with a prominent sign reading "MOONRISE."

8. Moonrise Hotel

14.7 mi from Lewis and Clark Interpretive Center

Nicole

$144 nightly

$171 total

Sep 29 - Sep 30

Total with taxes and fees

A multi-story hotel with balconies, a parking lot with marked spaces, and a clear sky.

A reception desk with a 'NO Pets Allowed' sign, a 'Please ring door bell' sign, and a window with a view of a parking lot.

A hotel room with two beds, each with a wooden headboard, white bedding, and a patterned bedspread.

A red door with a prohibition sign against tobacco, e-cigarettes, and cannabis.

9. Bel Air Motel

3.9 mi from Lewis and Clark Interpretive Center

Tai

$80 nightly

$89 total

Sep 27 - Sep 28

Total with taxes and fees

A modern lounge with a central fire feature, comfortable seating, and large windows offering a city view.

A rooftop terrace with a glass table, cushioned seating, and a view of the cityscape.

A bar area with wooden bar stools, a high counter, and a seating area with cushioned sofas and tables.

A rooftop bar with a glass railing, yellow bar stools, and a large umbrella.

10. Hilton St. Louis at the Ballpark

13.1 mi from Lewis and Clark Interpretive Center

$147 nightly

$175 total

Oct 2 - Oct 3

Total with taxes and fees

A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

A buffet area with various food items and a self-service station.

A spacious lobby with striped chairs, a central coffee table, and large potted plants.

A bar area with a long counter, multiple stools, and a television mounted on the wall.

11. Embassy Suites by Hilton St. Louis Downtown

12.8 mi from Lewis and Clark Interpretive Center

Karen

$114 nightly

$136 total

Oct 11 - Oct 12

Total with taxes and fees

A modern living room with a stone fireplace, a reception desk, and a large window.

A modern living room with a stone fireplace, green and beige sofas, a round coffee table, and large windows offering a view of trees.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and tables, large windows with a view of trees, and a tiled floor.

A Fairfield by Marriott hotel with a modern design, featuring a covered entrance and multiple floors.

12. Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

3.9 mi from Lewis and Clark Interpretive Center

Sabra

$105 nightly

$117 total

Oct 11 - Oct 12

Total with taxes and fees

A multi-story hotel with a prominent 'Marriott' sign, featuring a classic architectural style with a red brick facade and large windows.

A spacious interior with a central staircase, large windows, and hanging chandeliers.

A spacious lobby with a high ceiling, a bar area, multiple seating arrangements, and a large screen displaying a sports event.

13. Marriott St. Louis Grand

12.8 mi from Lewis and Clark Interpretive Center

Andrew

$152 nightly

$181 total

Oct 2 - Oct 3

Total with taxes and fees

A cozy lounge area with leather seating, a wooden coffee table, and a fireplace.

A hotel bathroom with a large bathtub, a sofa, a microwave, and a desk with a lamp.

A hotel room with a bed, a sofa, a desk, and a chair.

A hotel lobby with a beverage fridge, a television, and a seating area with a sofa and armchairs.

14. Best Western Plus Pontoon Beach

4.2 mi from Lewis and Clark Interpretive Center

Timothy

$103 nightly

$115 total

Sep 27 - Sep 28

Total with taxes and fees

A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.

A luxurious hotel lobby with a grand stage, elegant seating, and a large chandelier.

A casino with multiple gaming tables and slot machines.

A large hotel with a prominent "RIVER CITY" sign.

15. River City Casino & Hotel

20.7 mi from Lewis and Clark Interpretive Center

Ashley

$110 nightly

$129 total

Oct 15 - Oct 16

Total with taxes and fees

A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.

A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.

A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."

An indoor swimming pool with a 'SWIM FOR LIFE' sign, surrounded by patterned walls and windows.

16. 21C Museum Hotel St Louis

13 mi from Lewis and Clark Interpretive Center

Zane

$148 nightly

$173 total

Oct 18 - Oct 19

Total with taxes and fees

A modern interior with hanging chairs and ottomans, large windows with a view of the street.

A tall building with a grid of windows and a sign that reads "HOME 2".

A modern kitchen with a hexagonal tile backsplash, built-in appliances, and a central island.

A hallway with four elevators, each with a marble frame and a gold door.

17. Home2 Suites by Hilton St. Louis Downtown

12.9 mi from Lewis and Clark Interpretive Center

kaila

$98 nightly

$114 total

Oct 8 - Oct 9

Total with taxes and fees

A modern bathroom with a red bathtub, a white sink, and a shower. There is a bed with a white mattress and a grey curtain in the adjacent room.

A modern room with a stone wall, a flat-screen TV, two red chairs, a small table, and a view of the outside.

A modern kitchen with stainless steel appliances, a white countertop, and a framed picture on the wall.

A modern kitchen area with a dining table and chairs, a refrigerator, a coffee machine, and a vending machine.

18. Red Lion Inn & Suites Pontoon Beach

3.5 mi from Lewis and Clark Interpretive Center

Jennifer

$73 nightly

$82 total

Sep 27 - Sep 28

Total with taxes and fees

A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.

A bar area with wooden paneling, a counter, and multiple stools.

A lobby with wooden paneling, a green wall, and two armchairs.

A modern living room with a grey sofa, a round wooden coffee table, and a large window with a city view.

19. The Westin St. Louis

13.3 mi from Lewis and Clark Interpretive Center

Joanne

$131 nightly

$153 total

Oct 18 - Oct 19

Total with taxes and fees

A rooftop terrace with outdoor seating, string lights, and a city skyline view.

A multi-story hotel with a classic architectural style, featuring a prominent entrance and a series of uniformly lit windows.

A modern lounge area with a central cylindrical light fixture, white seating, and artwork on the walls.

A woman sitting on a green sofa in a modern lobby with a staircase and a large framed artwork on the wall.

20. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

13.2 mi from Lewis and Clark Interpretive Center

$118 nightly

$139 total

Oct 5 - Oct 6

Total with taxes and fees

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Compare popular hotels close to Lewis and Clark Interpretive Center

Property	Star rating	Guest rating
Comfort Inn Edwardsville - St. Louis	8.4 Very good 948 reviews	View
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City	9.2 Wonderful 529 reviews	View
Holiday Inn Express & Suites Edwardsville by IHG	9.2 Wonderful 910 reviews	View
Drury Inn & Suites St. Louis Collinsville	9.6 Exceptional 1,001 reviews	View
Best Western Plus Pontoon Beach	8.4 Very good 907 reviews	View

Top Lewis and Clark Interpretive Center Hotel Reviews

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

8/10 Good

"Great comfortable hotel with easy access and parking. Good location. Would stay again."

21C Museum Hotel St Louis

10/10 Excellent

"21C Museum St Louis is my favorite hotel. It is so vibrant. I love to swim and that YMCA pool built in the 1920s is gorgeous with hot tub and sauna. You get great coffee in the room, not the typical swill. The museum exhibits are thoughtfully curated and edgy. And they are featured in the old YMCA basketball court! Our room was lovely—the whole place is. This hotel is a destination for locals, it’s the place to be. Idol Wolf is the first outstanding restaurant experience I’ve had in a hotel."

Renaissance St. Louis Airport Hotel

10/10 Excellent

"We had a great experience at the hotel. The Internet you do have to pay extra for if you hook up your devices. Also parking is about $25 a night before taxes. All and all a good experience"

Live by Loews - St.Louis

10/10 Excellent

"Amazing. Such a great atmosphere!"

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"Great over all!!"

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent

"Great happy hour and breakfast."

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent

"Very pleasant and helpful staff."

Super 8 by Wyndham St. Louis North

8/10 Good

"It was fine. But not I a real safe neighbor hood"

Marriott St. Louis Grand

10/10 Excellent

"Amazing stay staff was unbelievable"

Other attractions near Lewis and Clark Interpretive Center

Lewis and Clark Confluence Tower

Bring a camera when you climb this tower, which offers fantastic views across the Mississippi River and provides insight into a fascinating piece of history.

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Lewis and Clark State Memorial Park

Explore the great outdoors at Lewis and Clark State Memorial Park, a lovely green space in Hartford. Discover the area's museums and monuments.

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Hartford Park

After visiting Hartford Park, make a plan to see the other sights and activities in Hartford. Discover the area's museums and monuments.

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Hartford City Hall

Hartford City Hall is just one of the places to see in Hartford, so why not enjoy the other things to explore during your travels? Amble around the area's riverfront or experience its museums.

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Jones-Confluence Point State Park

You can take time to visit Jones-Confluence Point State Park during your travels to West Alton. You can attend a sporting event while in the area.

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Dads Club Park

Explore the great outdoors at Dads Club Park, a lovely green space in South Roxana.

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South Roxana Dad's Club Park

South Roxana Dad's Club Park is just one of the places to see in South Roxana, so why not enjoy the other things to explore during your travels?

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Frequently asked questions

What are the top-rated hotels near Lewis and Clark Interpretive Center?

Discover the top-rated hotels near Lewis and Clark Interpretive Center, perfect for a comfortable and enjoyable stay in Hartford, Illinois.Bel Air MotelBel Air Motel boasts a solid review rating of 8.8 and is a cozy 3.5-star hotel located just 4.4 miles from Lewis and Clark Interpretive Center. Guests will appreciate the convenience of early check-in and late check-out options. The motel features essential amenities such as free toiletries and air conditioning, ensuring a comfortable stay. Additionally, travelers can enjoy the benefit of free self-parking during their visit.Red Lion Inn & Suites Pontoon BeachRated 8.0 by travelers, Red Lion Inn & Suites Pontoon Beach is situated 4.8 miles from Lewis and Clark Interpretive Center. This hotel offers a range of amenities including complimentary breakfast served daily and free self-parking. Guests can unwind in the private hot tub and enjoy the comfort of air conditioning in their rooms. The hotel is also equipped with mini-refrigerators, ensuring that travelers have everything they need for a pleasant stay.Econo Lodge & Suites Granite CityEcono Lodge & Suites Granite City has a review rating of 6.2 and is conveniently located just 3.6 miles from Lewis and Clark Interpretive Center. This hotel offers a continental breakfast to start the day right, along with free self-parking. Guests can enjoy the spacious suites featuring separate living rooms and premium bedding for added comfort. The hotel also provides daily housekeeping and free toiletries, making it a practical choice for travelers.

How much is a hotel near Lewis and Clark Interpretive Center?

Staying near Lewis and Clark Interpretive Center is a treat, with plenty of hotels from $71 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, especially in peak season. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a vacation during weekends or around public holidays.

What are the most popular family-friendly hotels near Lewis and Clark Interpretive Center?

For families looking to explore the Lewis and Clark Interpretive Center, there are several top-rated family-friendly hotels just a short drive away, ensuring a comfortable and convenient stay for all ages.Red Lion Inn & Suites Pontoon BeachRed Lion Inn & Suites Pontoon Beach is a welcoming family-friendly hotel located just 4.8 miles from the Lewis and Clark Interpretive Center, featuring a solid travelers' rating of 8.0. Families will appreciate the convenience of complimentary cribs and a mini-refrigerator in every room. Guests can also enjoy free continental breakfast and relax in the hot tub. Additional amenities include free parking, air conditioning, and early check-in to make your family trip even smoother.Econo Lodge & Suites Granite CityEcono Lodge & Suites Granite City offers a budget-friendly stay just 3.6 miles from the Lewis and Clark Interpretive Center, with a review rating of 6.2. This family-friendly hotel provides daily housekeeping and free accommodations for children, ensuring a straightforward experience. Guests can benefit from amenities such as a microwave in each room, free continental breakfast, and spacious suites with premium bedding, making it an ideal choice for families.

What are the best affordable hotels near Lewis and Clark Interpretive Center?

For an affordable stay close to the Lewis and Clark Interpretive Center, these top-rated hotels offer great amenities without breaking the bank.Red Lion Inn & Suites Pontoon BeachRed Lion Inn & Suites Pontoon Beach is a cozy 3-star hotel located just 4.8 miles from the Lewis and Clark Interpretive Center, a solid travelers' rating of 8.0. This family-friendly hotel offers free daily breakfast, complimentary Wi-Fi, and self-parking, ensuring a comfortable stay for all travelers. Enjoy the convenience of air-conditioned rooms equipped with mini-refrigerators and the option for early check-in, making it an ideal choice for families on a budget.Econo Lodge & Suites Granite CityEcono Lodge & Suites Granite City is a budget-friendly hotel situated only 3.6 miles from the Lewis and Clark Interpretive Center, with a review rating of 6.2. This hotel features essential amenities like free continental breakfast, Wi-Fi, and self-parking, making it a practical choice for travelers. Guests can enjoy spacious suites with separate living areas and daily housekeeping, ensuring a pleasant stay for families and groups alike.

What are the best pet-friendly hotels near Lewis and Clark Interpretive Center?

For travelers looking for the best pet-friendly hotels near the Lewis and Clark Interpretive Center, these accommodations provide a welcoming atmosphere for you and your furry friends.Red Lion Inn & Suites Pontoon BeachRed Lion Inn & Suites Pontoon Beach is a welcoming 3-star hotel located just 4.8 miles from the Lewis and Clark Interpretive Center. With a review rating of 8.0, this hotel is perfect for travelers traveling with pets, as it offers amenities such as pet-friendly rooms and services. Guests can enjoy free continental breakfast, early check-in, and access to a hot tub. Additional features include air conditioning, mini-refrigerators, and free self-parking.Econo Lodge & Suites Granite CityEcono Lodge & Suites Granite City is situated only 3.6 miles from the Lewis and Clark Interpretive Center, making it a convenient choice for travelers. Rated 6.2 by travelers, this hotel provides a comfortable stay with pet-friendly policies. Guests will appreciate the complimentary continental breakfast, daily housekeeping, and the convenience of in-room microwaves. The hotel also features suites with separate living rooms, allowing for extra space during your stay.

Can I book a fully refundable hotel close to Lewis and Clark Interpretive Center?

Most bookings on Expedia are refundable if canceled within 24-48 hours of arrival, though this depends on the hotel's individual cancellation policy, which you should check in your booking confirmation. If free cancellation is available, you can cancel directly through your Expedia account by going to "My Trips" and selecting your reservation. To find fully refundable hotel options, simply enter "Lewis and Clark Interpretive Center", set your travel dates, and use the "Fully refundable" filter under "Deals & Discounts" on the results page. Alternatively, explore deals with free cancellation options on Expedia.

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Things to do in Fairview Heights

Find hotels near Lewis and Clark Interpretive Center, St. Louis from $71

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Be picky

Check prices for these dates

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Our top choices for Lewis and Clark Interpretive Center hotels

1. Hyatt Regency St. Louis at The Arch

2. Econo Lodge Inn & Suites Granite City - St. Louis

3. Budget Motel Granite City/St Louis Area

4. Clayton Plaza Hotel & Extended Stay

5. Drury Plaza Hotel St. Louis at the Arch

6. Live by Loews - St.Louis

7. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

8. Moonrise Hotel

9. Bel Air Motel

10. Hilton St. Louis at the Ballpark

11. Embassy Suites by Hilton St. Louis Downtown

12. Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

13. Marriott St. Louis Grand

14. Best Western Plus Pontoon Beach

15. River City Casino & Hotel

16. 21C Museum Hotel St Louis

17. Home2 Suites by Hilton St. Louis Downtown

18. Red Lion Inn & Suites Pontoon Beach

19. The Westin St. Louis

20. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Compare popular hotels close to Lewis and Clark Interpretive Center

Top Lewis and Clark Interpretive Center Hotel Reviews

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

21C Museum Hotel St Louis

Renaissance St. Louis Airport Hotel

Live by Loews - St.Louis

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis Union Station

Pear Tree Inn St. Louis Near Union Station

Super 8 by Wyndham St. Louis North

Marriott St. Louis Grand

Other attractions near Lewis and Clark Interpretive Center

Lewis and Clark Confluence Tower

Lewis and Clark State Memorial Park

Hartford Park

Hartford City Hall

Jones-Confluence Point State Park

Dads Club Park

South Roxana Dad's Club Park

Frequently asked questions

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