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Find hotels in Lyon, MS from $87

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Jul 3 - Jul 5
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Our top choices for Lyon hotels

Lobby

Isle Casino Hotel Lula Hotel & Casino - A Caesars Rewards Destination

Isle Casino Hotel Lula Hotel & Casino - A Caesars Rewards Destination
2.5 star property
Lula
6.4 out of 10, (1,001 reviews)
"The property was pretty clean and the people at the front desk was helpful."
United States
Elizabeth
1 day ago
$71 nightly
The price is $77
Jul 5 - Jul 6
Total with taxes and fees
Isle Casino Hotel Lula Hotel & Casino - A Caesars Rewards Destination
Reception

Hampton Inn Clarksdale

Hampton Inn Clarksdale
2.5 star property
Clarksdale
8.2 out of 10, Very Good, (383 reviews)
"Great breakfast, clean room, convenience parking."
United States
Gail or Derrick
17 days ago
$144 nightly
The price is $157
Jul 12 - Jul 13
Total with taxes and fees
Hampton Inn Clarksdale
Exterior

Travelers Hotel

Travelers Hotel
2.5 star property
Clarksdale
9.8 out of 10, Exceptional, (308 reviews)
"Unassuming eclectic space with a very convenient serve yourself setup."
United States
Rebecca
11 days ago
$143 nightly
The price is $156
Jul 4 - Jul 5
Total with taxes and fees
Travelers Hotel
Lobby sitting area

Quality Inn Clarksdale

Quality Inn Clarksdale
2.5 star property
Clarksdale
7.4 out of 10, Good, (751 reviews)
"The staff was wonderful. Everything else was excellent."
United States
William
May 18th, 2026
$80 nightly
The price is $87
Jul 23 - Jul 24
Total with taxes and fees
Quality Inn Clarksdale
Lobby

Americas Best Value Inn & Suites Clarksdale

Americas Best Value Inn & Suites Clarksdale
2.5 star property
Clarksdale
6.0 out of 10, (421 reviews)
"The property could use some updating. It was clean and got the job done!"
United States
Iesha
$80 nightly
The price is $87
Jul 5 - Jul 6
Total with taxes and fees
Americas Best Value Inn & Suites Clarksdale
Property entrance

Delta Inn West Helena US 49 AR

Delta Inn West Helena US 49 AR
2.0 star property
West Helena
6.6 out of 10, (410 reviews)
"Found the Delta Inn it a perfect stopover on my drive Ms. Staff was professional."
United States
Glen
April 13th, 2026
$51 nightly
The price is $58
Jul 6 - Jul 7
Total with taxes and fees
Delta Inn West Helena US 49 AR
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay near Lyon

Lyon offers a delightful blend of outdoor adventures and scenic beauty. Explore family-friendly neighborhoods and enjoy romantic strolls amidst nature. Whether hiking, picnicking, or simply soaking in the atmosphere, you'll find plenty of opportunities for unforgettable experiences in and around this charming city.
A colorful car parked in front of a mural on a city street.
Photo by Alice Andersen
Open Photo by Alice Andersen

Clarksdale

Discover Clarksdale, a vibrant destination perfectly suited for cultural enthusiasts and music lovers seeking an authentic Southern experience. Explore the rich heritage at the Delta Blues Museum, enjoy live performances at the iconic Ground Zero Blues Club, and immerse yourself in the local scene around Coahoma Community College. Just about a 2-mile drive from Lyon, Clarksdale offers easy access for visitors. With its unique blend of music, culture, and outdoor activities, Clarksdale is a smart choice for your next getaway.

Jonestown

Plan your stay in Jonestown, a top-rated choice for families and budget travelers looking for a mix of outdoor adventures and cultural experiences. This charming village offers easy access to attractions like Coahoma Community College and the Rock N' Roll & Blues Heritage Museum, perfect for those wanting to explore the local arts scene. With a drive of about 14 miles from Lyon, Jonestown is a smart choice for your next vacation getaway.

Coahoma

Make your vacation planning effortless by staying in Coahoma, a haven for family and budget travelers thanks to its diverse attractions. Enjoy the vibrant local culture at the Rock N' Roll & Blues Heritage Museum, relax in the scenic Freedom Park, and explore Coahoma Community College. With its welcoming atmosphere and recreational options, Coahoma is a smart choice for travelers seeking both entertainment and relaxation. Plus, it's only about a 10-mile drive from Lyon, making it easy to reach.

Alligator

Ideally situated for budget-conscious families and nature enthusiasts, Alligator offers a charming escape just about 16 miles by car from Lyon. Here, visitors can immerse themselves in outdoor adventures, explore the scenic beauty of nearby state parks, and enjoy local landmarks like the Delta Blues Museum and Ground Zero Blues Club. With a blend of education and recreation, Alligator provides a welcoming atmosphere for travelers looking to experience the best of Mississippi's culture and scenery. It's a smart choice for your vacation stay.

Lambert

Travelers visiting the area often choose Lambert, especially families and outdoor enthusiasts seeking a charming village atmosphere. With attractions like the Hobson Plantation bar, the Coahoma Community College, and the Rock N' Roll & Blues Heritage Museum, Lambert offers a blend of cultural and recreational experiences. Located about 24 miles by car from Lyon, it provides easy access to a peaceful getaway while still being close to urban conveniences. Lambert is a smart choice for those looking to unwind and explore Mississippi's unique offerings.

Stay near popular attractions around Lyon

Nestled in the heart of Mississippi, Lyon offers a perfect blend of outdoor adventures and cultural experiences. Discover local museums and galleries, and admire beautiful monuments. Whether you seek scenic hikes or family-friendly attractions, Lyon promises an unforgettable getaway for every traveler.

Delta Blues Museum

9.0/10 (83 reviews)
Set the stage for your exploration of American music at the Delta Blues Museum, a vibrant tribute to the rich heritage of blues music. Located about 2 miles by car from Lyon, this museum offers an immersive experience into the culture and history of the Delta blues. Staying nearby makes it easy to soak in the musical legacy of the region.
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Top Lyon Hotel Reviews

Travelers Hotel

Travelers Hotel

10/10 Excellent
"A beautiful and unique place to stay in Clarksdale! The decor in lobby is fantastic and such a welcoming vibe. The honor bar and breakfast supplies were most appreciated. Every detail is thought of. Rooms are simple, comfortable and cool! Highly recommend!"
Jessie 1-night trip
Posted 23 hours ago
Travelers Hotel

More cheap stays in Lyon

Quality Inn Clarksdale

Quality Inn Clarksdale

818 South State Street Clarksdale MS
$80 nightly
The price is $87 total per night from Jul 23 to Jul 24
$87 total
Jul 23 - Jul 24
Total with taxes and fees
7.4/10 Good! (751 reviews)

Hotels in Lyon with star-rating

Frequently asked questions

What is the best area to stay in Lyon?
The best area to stay in Lyon, Mississippi, is near the intersection of Highway 61 and Highway 161, which provides convenient access to local amenities and the surrounding region.

This area is the primary hub for visitors passing through Lyon. It offers easy access to the main roads, making it a practical choice for those exploring the Mississippi Delta. You'll find a few local eateries and essential services concentrated around these major thoroughfares.

For solo travelers or couples on a road trip, this location is ideal.
When is the best time to go to Lyon?
The best time to visit Lyon, Mississippi, is during the spring (March to May) and fall (September to November) months, when the weather is most pleasant for exploring.

Spring offers mild temperatures, typically ranging from the 60s to high 70s Fahrenheit, making it comfortable for outdoor activities and enjoying the natural beauty of the Mississippi Delta. This season is ideal for travelers who appreciate comfortable weather for sightseeing and general exploration without the intense heat of summer.

Similarly, the fall season brings cooler temperatures, generally from the 60s to low 80s Fahrenheit, and lower humidity. This period is superb for those looking to experience the local culture and history in comfort.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Lyon.
How can I save on a Lyon hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Lyon hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Lyon hotel?
Prices for hotels in Lyon often vary, but you can find a great deal from $87 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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