Clarksdale Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Clarksdale Vacation

Experience the excitement and energy of Clarksdale with a tailor-made Clarksdale vacation package. From its rich history to its cultural experiences, you'll never have a boring moment in this city. Make your trip to Clarksdale even more exciting by going sightseeing. Delta Blues Museum, Rock and Blues Museum and Reds Lounge are some of the most popular attractions you'll want to explore. No matter your travel plans or the size of your budget, putting together a tailored Clarksdale vacation is easy with Expedia.

Stay near popular Clarksdale attractions

Ground Zero Blues Club

Step into this authentic juke joint co-owned by Morgan Freeman for soulful Delta blues performances. Savor Southern comfort food while listening to emerging and established artists in a memorabilia-filled setting.
See properties

Delta Blues Museum

9.0/10 (83 reviews)
The world's first blues museum preserves the rich legacy of this uniquely American art form. Explore Muddy Waters' restored cabin and immerse yourself in the soulful sounds that shaped modern music.
See properties

Red's Lounge

8.6/10 (56 reviews)
Step inside one of Mississippi's last authentic juke joints where blues legends perform mere feet away. Red's intimate, no-frills atmosphere delivers raw Delta blues in its purest form—bring cash for the cover charge.
See properties

Rock N' Roll & Blues Heritage Museum

8.8/10 (19 reviews)
This former museum housed rare albums and artifacts tracing American music from the 1920s through the 1970s. Though permanently closed since 2019, its legacy celebrates the evolution from blues to rock 'n' roll.
See properties

The Holy Moly Theatre

7.8/10 (13 reviews)
This historic 1923 Masonic temple now hosts intimate performances celebrating the Mississippi Delta's rich artistic heritage. Experience local talent amid architectural charm during evening shows of music and theater.
See properties

The Crossroads

At this legendary intersection, Robert Johnson reportedly sold his soul to the devil for blues mastery. Stand among the three guitar monuments where Highway 61 meets 49 and feel the weight of musical history.
See properties

Hambone Art Gallery

9.0/10 (22 reviews)
At Hambone Art Gallery, Stan Street's vibrant artwork mingles with live blues music. Experience Clarksdale's cultural heartbeat Tuesdays when local musicians transform the gallery into an intimate concert venue.
See properties

New Roxy

8.4/10 (20 reviews)
This historic open-air venue celebrates Mississippi's blues heritage with live performances against rustic brick walls. Experience authentic Delta culture under the stars during the Deep Blues Festival in October.
See properties

Clarksdale Hotel Deals

Quality Inn Clarksdale

Quality Inn Clarksdale

818 South State Street Clarksdale MS
Fully refundable
$82 nightly
$90 total
Sep 17 - Sep 18
Total with taxes and fees
7.2/10 Good! (769 reviews)
"I liked that I had access to a hot breakfast every day except for Sunday, I don’t like that breakfast wasn’t available Sunday. I didn’t like that there wasn’t any clean face towels for 2 days. I didn’t like that the tub and toilet had rust stains."

Reviewed on Aug 17, 2026

Quality Inn Clarksdale
Hampton Inn Clarksdale

Hampton Inn Clarksdale

15000 New Africa Rd Clarksdale MS
Fully refundableReserve now, pay when you stay
$130 nightly
$142 total
Aug 30 - Aug 31
Total with taxes and fees
Hampton Inn Clarksdale
Travelers Hotel

Travelers Hotel

212 3rd St Clarksdale MS
Fully refundableReserve now, pay when you stay
$151 nightly
$165 total
Sep 16 - Sep 17
Total with taxes and fees
9.8/10 Exceptional! (315 reviews)
"Hotel was very clean and room had excellent air conditioning. There was a little confusion over checking in. There was a piece of paper on the counter with our checkin info. Other than that no problems."

Reviewed on Aug 17, 2026

Travelers Hotel
See all 58 properties in Clarksdale
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Clarksdale Vacation Packages

Clarksdale Essential Information

Language
English
Currency
U.S dollars
Population
16,800
Max Temp Winter
50ºF
Max Temp Summer
90ºF
Top Sights
The Holy Moly Theatre, Delta Blues Museum and Rock and Blues Museum

More vacations you might like

Frequently asked questions

How much does a Clarksdale vacation package cost?
You can snap up a vacation package to this popular destination on Expedia. However, how much your vacation to Clarksdale costs will depend on factors like the season, hotel choice and length of stay.
What are the cheapest months to go to Clarksdale?
November, December and January are the best times to look for cheap Clarksdale vacation packages. Opting to travel in less busy months means you can typically find lower prices on flights and hotels.
How many days is enough for Clarksdale?
With a well-planned schedule, you can easily tick off the top Clarksdale sights in a handful of days. But if you'd like to discover hidden gems or go on day trips, think about booking your Clarksdale vacation for longer.
Is it worth booking a vacation package to Clarksdale?
Clarksdale has everything you need for an unforgettable escape. Begin your Clarksdale vacation on a high note by visiting popular attractions like Delta Blues Museum.
How to find the best Clarksdale package deals?
Finding a cheap Clarksdale package deal is easy with Expedia. Once you've entered your destination and preferred dates under our "Packages" tab, set your budget, apply a few filters and browse what's available. You can tailor your search by "Popular locations," "Property type," "Guest rating" and more. Sort the results by "Price: low to high" to discover the most economical Clarksdale package deals. Want a simple trick to score the biggest savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are often lower.
Is it cheaper to book a Clarksdale vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to booking flights and accommodations separately. Better still, you can personalize your Clarksdale getaway to fit your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Check out our great deals to see how much you can save.
When to book a vacation package to Clarksdale?
If you're planning a spur-of-the-moment Clarksdale trip, browse our last-minute deals that can be booked up to one week before you take off. Prefer not to wait until the last minute? You can land amazing deals on your flights and hotels by booking ahead.
Does Expedia offer Book Now, Pay Later Clarksdale vacation packages?
Set off on your perfect escape to Clarksdale with help from Expedia's Book Now, Pay Later vacations. No need to save like crazy or wait until your next paycheck — we've teamed up with online lender Affirm to give you flexibility and choice. Our vacation packages with payment plans mean you can spread the cost over 3, 6 or 12 months. With no hidden or late payment fees, it's a breeze to stick to your budget and snap up bargains while they last.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.