Clarksdale Vacations from $376

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Your Clarksdale Vacation

Experience the excitement and energy of Clarksdale with a tailor-made Clarksdale vacation package. From its rich history to its cultural experiences, you'll never have a boring moment in this city. Make your trip to Clarksdale even more exciting by going sightseeing. Delta Blues Museum, Rock and Blues Museum and Reds Lounge are some of the most popular attractions you'll want to explore. No matter your travel plans or the size of your budget, putting together a tailored Clarksdale vacation is easy with Expedia.

The Latest Clarksdale vacation packages

Price found within the past 48 hours. Click for updated prices.
Dreamland Inn and Suites

Dreamland Inn and Suites

$376
per person
Sep 18 - Sep 20
found 1 day ago
Roundtrip non-stop flight included
Baltimore (BWI) to Greenville (GLH)
7/10 Good! (64 reviews)
Clean rooms, great customer service

Reviewed on Aug 13, 2026

Ruleville Inn By OYO

Ruleville Inn By OYO

$1,139
per person
Sep 17 - Sep 20
found 1 day ago
Roundtrip non-stop flight included
Ontario Intl. Airport (ONT) to Greenville (GLH)
5.6/10 (56 reviews)
It is quiet. The property is clean.

Reviewed on May 29, 2026

Southern Inn Lake Village Near Greenville MS 1

Southern Inn Lake Village Near Greenville MS 1

$654
per person
Sep 22 - Sep 25
found 1 day ago
Roundtrip non-stop flight included
Baltimore (BWI) to Greenville (GLH)
2/10 (3 reviews)
Address was wrong never found hotel still got charged

Reviewed on Aug 10, 2026

Turn On Inn

Turn On Inn

$821
per person
Sep 22 - Sep 25
found 1 day ago
Roundtrip non-stop flight included
Baltimore (BWI) to Greenville (GLH)
9.6/10 Exceptional! (91 reviews)
Red Leaf Cottages

Red Leaf Cottages

$821
per person
Sep 22 - Sep 25
found 1 day ago
Roundtrip non-stop flight included
Baltimore (BWI) to Greenville (GLH)
9/10 Wonderful! (25 reviews)
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Stay near popular Clarksdale attractions

Ground Zero Blues Club

Step into this authentic juke joint co-owned by Morgan Freeman for soulful Delta blues performances. Savor Southern comfort food while listening to emerging and established artists in a memorabilia-filled setting.
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Delta Blues Museum

9.0/10 (83 reviews)
The world's first blues museum preserves the rich legacy of this uniquely American art form. Explore Muddy Waters' restored cabin and immerse yourself in the soulful sounds that shaped modern music.
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Red's Lounge

8.6/10 (56 reviews)
Step inside one of Mississippi's last authentic juke joints where blues legends perform mere feet away. Red's intimate, no-frills atmosphere delivers raw Delta blues in its purest form—bring cash for the cover charge.
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Rock N' Roll & Blues Heritage Museum

8.8/10 (19 reviews)
This former museum housed rare albums and artifacts tracing American music from the 1920s through the 1970s. Though permanently closed since 2019, its legacy celebrates the evolution from blues to rock 'n' roll.
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The Crossroads

At this legendary intersection, Robert Johnson reportedly sold his soul to the devil for blues mastery. Stand among the three guitar monuments where Highway 61 meets 49 and feel the weight of musical history.
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Quapaw Canoe Company

8.6/10 (14 reviews)
Explore the Mississippi's untamed wilderness with expert guides in handcrafted wooden canoes. Paddle through serene backwaters, spot diverse wildlife, and camp on remote sandbars during multi-day expeditions.
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Carnegie Public Library

10.0/10 (4 reviews)
This 1914 Andrew Carnegie-funded library stands as a historical educational hub in Clarksdale. Browse its diverse collection or join community programs in the charming early 20th-century building.
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The Holy Moly Theatre

7.8/10 (13 reviews)
This historic 1923 Masonic temple now hosts intimate performances celebrating the Mississippi Delta's rich artistic heritage. Experience local talent amid architectural charm during evening shows of music and theater.
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Clarksdale Hotel Deals

Quality Inn Clarksdale

Quality Inn Clarksdale

818 South State Street Clarksdale MS
Fully refundable
$84 nightly
$91 total
Sep 10 - Sep 11
Total with taxes and fees
7.2/10 Good! (768 reviews)
"No working air conditioning, smelly carpet just not livable."

Reviewed on Aug 15, 2026

Quality Inn Clarksdale
Hampton Inn Clarksdale

Hampton Inn Clarksdale

15000 New Africa Rd Clarksdale MS
Fully refundableReserve now, pay when you stay
$132 nightly
$144 total
Sep 13 - Sep 14
Total with taxes and fees
8.2/10 Very Good! (399 reviews)
"Everything was fine."

Reviewed on Aug 13, 2026

Hampton Inn Clarksdale
Travelers Hotel

Travelers Hotel

212 3rd St Clarksdale MS
Fully refundableReserve now, pay when you stay
$154 nightly
$168 total
Aug 24 - Aug 25
Total with taxes and fees
9.8/10 Exceptional! (314 reviews)
"Loved this place. The room Did have a smell but it wasn’t horrible. It was clean and nice"

Reviewed on Aug 15, 2026

Travelers Hotel
See all 58 properties in Clarksdale
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Clarksdale Vacation Packages

Clarksdale Essential Information

Language
English
Currency
U.S dollars
Population
16,800
Max Temp Winter
50ºF
Max Temp Summer
90ºF
Top Sights
The Holy Moly Theatre, Delta Blues Museum and Rock and Blues Museum

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Frequently asked questions

How much does a Clarksdale vacation package cost?
You can snap up a vacation package to this popular destination from $376 on Expedia. However, how much your vacation to Clarksdale costs will depend on factors like the season, hotel choice and length of stay.
What are the cheapest months to go to Clarksdale?
November, December and January are the best times to look for cheap Clarksdale vacation packages. Opting to travel in less busy months means you can typically find lower prices on flights and hotels.
How many days is enough for Clarksdale?
With a well-planned schedule, you can easily tick off the top Clarksdale sights in a handful of days. But if you'd like to discover hidden gems or go on day trips, think about booking your Clarksdale vacation for longer.
Is it worth booking a vacation package to Clarksdale?
Clarksdale has everything you need for an unforgettable escape. Begin your Clarksdale vacation on a high note by visiting popular attractions like Delta Blues Museum.
How to find the best Clarksdale package deals?
Finding a cheap Clarksdale package deal is easy with Expedia. Once you've entered your destination and preferred dates under our "Packages" tab, set your budget, apply a few filters and browse what's available. You can tailor your search by "Popular locations," "Property type," "Guest rating" and more. Sort the results by "Price: low to high" to discover the most economical Clarksdale package deals. Want a simple trick to score the biggest savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are often lower.
Is it cheaper to book a Clarksdale vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to booking flights and accommodations separately. Better still, you can personalize your Clarksdale getaway to fit your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Check out our great deals to see how much you can save.
When to book a vacation package to Clarksdale?
If you're planning a spur-of-the-moment Clarksdale trip, browse our last-minute deals that can be booked up to one week before you take off. Prefer not to wait until the last minute? You can land amazing deals on your flights and hotels by booking ahead.
Does Expedia offer Book Now, Pay Later Clarksdale vacation packages?
Set off on your perfect escape to Clarksdale with help from Expedia's Book Now, Pay Later vacations. No need to save like crazy or wait until your next paycheck — we've teamed up with online lender Affirm to give you flexibility and choice. Our vacation packages with payment plans mean you can spread the cost over 3, 6 or 12 months. With no hidden or late payment fees, it's a breeze to stick to your budget and snap up bargains while they last.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.