Clarksdale Vacations from $272

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Your Clarksdale Vacation

Experience the excitement and energy of Clarksdale with a tailor-made Clarksdale vacation package. From its rich history to its cultural experiences, you'll never have a boring moment in this city. Make your trip to Clarksdale even more exciting by going sightseeing. Delta Blues Museum, Rock and Blues Museum and Reds Lounge are some of the most popular attractions you'll want to explore. No matter your travel plans or the size of your budget, putting together a tailored Clarksdale vacation is easy with Expedia.

The Latest Clarksdale vacation packages

Price found within the past 48 hours. Click for updated prices.
Southern Inn Lake Village Near Greenville MS 1

Southern Inn Lake Village Near Greenville MS 1

$272
per person
Sep 24 - Sep 27
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Greenville (GLH)
2/10 (3 reviews)
Tv didn’t work No hot water Took till 2a.m for room to cool down Property had trash in shopping cars , broke down vehicles and mattresses out side Had to call a number and wait 15min for someone to come check me in Had to fill out my own information on there card I wont return

Reviewed on Aug 3, 2026

Turn On Inn

Turn On Inn

$437
per person
Sep 24 - Sep 27
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Greenville (GLH)
9.6/10 Exceptional! (91 reviews)
Red Leaf Cottages

Red Leaf Cottages

$430
per person
Sep 24 - Sep 27
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Greenville (GLH)
9/10 Wonderful! (25 reviews)
c towninn and suites

c towninn and suites

$276
per person
Sep 24 - Sep 27
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Greenville (GLH)
5/10 (20 reviews)
Holiday Inn Express Hotel & Suites Cleveland by IHG

Holiday Inn Express Hotel & Suites Cleveland by IHG

$407
per person
Sep 24 - Sep 27
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Greenville (GLH)
7.8/10 Good! (984 reviews)
The staff was accommodating. The key card system was not working so there was not a key card to get into your room. Each time you needed to get into your room a member of the staff had to go to the room with you to open the door. The lunch room was under construction. The small area for breakfast and coffee was not pleasant. Went across the street to get coffee instead. Room coffee pot was dirty. My first room the air conditioner was leaking and the carpet was wet. I was moved to another room and the refrigerator leaked. I put a towel on the floor and stayed in that room. The bathroom commode had bad stains. The shower drain had what looked like mold around it. The elevator walls were torn with a big hole. The "under construction" was not noted on the website at all. Probably would not have stayed there if we knew this.

Reviewed on Aug 8, 2026

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Stay near popular Clarksdale attractions

Delta Blues Museum

9.0/10 (83 reviews)
The world's first blues museum preserves the rich legacy of this uniquely American art form. Explore Muddy Waters' restored cabin and immerse yourself in the soulful sounds that shaped modern music.
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Ground Zero Blues Club

Step into this authentic juke joint co-owned by Morgan Freeman for soulful Delta blues performances. Savor Southern comfort food while listening to emerging and established artists in a memorabilia-filled setting.
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Rock N' Roll & Blues Heritage Museum

8.8/10 (19 reviews)
This former museum housed rare albums and artifacts tracing American music from the 1920s through the 1970s. Though permanently closed since 2019, its legacy celebrates the evolution from blues to rock 'n' roll.
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Red's Lounge

8.6/10 (56 reviews)
Step inside one of Mississippi's last authentic juke joints where blues legends perform mere feet away. Red's intimate, no-frills atmosphere delivers raw Delta blues in its purest form—bring cash for the cover charge.
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Hambone Art Gallery

9.0/10 (22 reviews)
At Hambone Art Gallery, Stan Street's vibrant artwork mingles with live blues music. Experience Clarksdale's cultural heartbeat Tuesdays when local musicians transform the gallery into an intimate concert venue.
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The Crossroads

At this legendary intersection, Robert Johnson reportedly sold his soul to the devil for blues mastery. Stand among the three guitar monuments where Highway 61 meets 49 and feel the weight of musical history.
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Carnegie Public Library

10.0/10 (4 reviews)
This 1914 Andrew Carnegie-funded library stands as a historical educational hub in Clarksdale. Browse its diverse collection or join community programs in the charming early 20th-century building.
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Quapaw Canoe Company

8.6/10 (14 reviews)
Explore the Mississippi's untamed wilderness with expert guides in handcrafted wooden canoes. Paddle through serene backwaters, spot diverse wildlife, and camp on remote sandbars during multi-day expeditions.
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Clarksdale Hotel Deals

Quality Inn Clarksdale

Quality Inn Clarksdale

818 South State Street Clarksdale MS
Fully refundable
$80 nightly
$87 total
Aug 31 - Sep 1
Total with taxes and fees
7.2/10 Good! (765 reviews)
"All good. Staff is a big plus."

Reviewed on Aug 6, 2026

Quality Inn Clarksdale
Hampton Inn Clarksdale

Hampton Inn Clarksdale

15000 New Africa Rd Clarksdale MS
Fully refundableReserve now, pay when you stay
$130 nightly
$142 total
Aug 23 - Aug 24
Total with taxes and fees
8.2/10 Very Good! (396 reviews)
"Every time we come to Mississippi we always visit the Hampton Inn. Always nice and clean and we look forward to the breakfast"

Reviewed on Aug 9, 2026

Hampton Inn Clarksdale
Travelers Hotel

Travelers Hotel

212 3rd St Clarksdale MS
Fully refundableReserve now, pay when you stay
$149 nightly
$162 total
Aug 10 - Aug 11
Total with taxes and fees
9.8/10 Exceptional! (313 reviews)
"It was clean, within walking distance of blues club, museum and restaurants."

Reviewed on Aug 7, 2026

Travelers Hotel
See all 57 properties in Clarksdale
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Clarksdale Vacation Packages

Clarksdale Essential Information

Language
English
Currency
U.S dollars
Population
16,800
Max Temp Winter
50ºF
Max Temp Summer
90ºF
Top Sights
The Holy Moly Theatre, Delta Blues Museum and Rock and Blues Museum

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Frequently asked questions

How much does a Clarksdale vacation package cost?
You can snap up a vacation package to this popular destination from $272 on Expedia. However, how much your vacation to Clarksdale costs will depend on factors like the season, hotel choice and length of stay.
What are the cheapest months to go to Clarksdale?
November, December and January are the best times to look for cheap Clarksdale vacation packages. Opting to travel in less busy months means you can typically find lower prices on flights and hotels.
How many days is enough for Clarksdale?
With a well-planned schedule, you can easily tick off the top Clarksdale sights in a handful of days. But if you'd like to discover hidden gems or go on day trips, think about booking your Clarksdale vacation for longer.
Is it worth booking a vacation package to Clarksdale?
Clarksdale has everything you need for an unforgettable escape. Begin your Clarksdale vacation on a high note by visiting popular attractions like Delta Blues Museum.
How to find the best Clarksdale package deals?
Finding a cheap Clarksdale package deal is easy with Expedia. Once you've entered your destination and preferred dates under our "Packages" tab, set your budget, apply a few filters and browse what's available. You can tailor your search by "Popular locations," "Property type," "Guest rating" and more. Sort the results by "Price: low to high" to discover the most economical Clarksdale package deals. Want a simple trick to score the biggest savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are often lower.
Is it cheaper to book a Clarksdale vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to booking flights and accommodations separately. Better still, you can personalize your Clarksdale getaway to fit your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Check out our great deals to see how much you can save.
When to book a vacation package to Clarksdale?
If you're planning a spur-of-the-moment Clarksdale trip, browse our last-minute deals that can be booked up to one week before you take off. Prefer not to wait until the last minute? You can land amazing deals on your flights and hotels by booking ahead.
Does Expedia offer Book Now, Pay Later Clarksdale vacation packages?
Set off on your perfect escape to Clarksdale with help from Expedia's Book Now, Pay Later vacations. No need to save like crazy or wait until your next paycheck — we've teamed up with online lender Affirm to give you flexibility and choice. Our vacation packages with payment plans mean you can spread the cost over 3, 6 or 12 months. With no hidden or late payment fees, it's a breeze to stick to your budget and snap up bargains while they last.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.