Massachusetts may have travel restrictions in place, including self-quarantine, due to COVID-19.

Find out moreOpens in new tab or window

Main Street HyannisUnited States of America

Find HotelsFind Flights

Escape to Main Street Hyannis! Enjoy its food and beaches.

Discover the walkable city of Main Street Hyannis—restaurants, beaches, and sights from John F. Kennedy Hyannis Museum to Cape Cod Baseball Hall of Fame.

Top Hotels in Main Street Hyannis

Hyannis Plaza Hotel
Hyannis Plaza Hotel
2.5 out of 5
662 Main Street, Hyannis, MA
The price is $70 per night from Jan 25 to Jan 26

Located in the heart of Hyannis, this luxury hotel is within 1 mi (2 km) of Cape Cod Carousel and Hyannis Harbor. Cape Codder Water Park is 2.2 mi (3.6 km) away. ...…

3/5 (90 reviews)

"I like how the bathroom was very clean and the hot tub was absolutely amazing. We loved it and I’d go back again."…"

Reviewed on Jan 18, 2021

Hyannis Plaza Hotel
Heritage House Hotel
Heritage House Hotel
2.5 out of 5
259 Main Street, Hyannis, MA
The price is $89 per night from Jan 25 to Jan 26

Located in the heart of Hyannis, this hotel is within a 10-minute walk of John F. Kennedy Hyannis Museum and Hyannis Harbor. Cape Cod Carousel and St. Francis ...…

3.5/5Good! (998 reviews)
Great Location

"Wonderful, great staff."…"

Reviewed on Oct 19, 2020

Heritage House Hotel
Americas Best Value Inn & Suites Hyannis Cape Cod
Americas Best Value Inn & Suites Hyannis Cape Cod
2 out of 5
206 Main St, Hyannis, MA
Get Rates

Located in the heart of Hyannis, this hotel is within a 10-minute walk of Cape Cod Maritime Museum and Hyannis Harbor. Cape Codder Water Park is 2.5 mi (4 km) ...…

3.4/5 (998 reviews)

"Our stay was good. Accessible and clean. My only comment is they should provide coffeemaker and mucrowave every room. Instead of walking to the office to get coffee. And heat food. Thst i would give a 10."…"

Reviewed on Sep 27, 2020

Americas Best Value Inn & Suites Hyannis Cape Cod
See all 4451 properties in Main Street Hyannis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Vacation Rentals in Main Street Hyannis

The Club at New Seabury
The Club at New Seabury
3.5 out of 5
95 Shore Drive West, Mashpee, MA
The price is $142 per night from Jan 25 to Jan 26

Situated in Mashpee, this beach condo resort is 0.8 mi (1.3 km) from South Cape Beach State Park and 2.5 mi (4.1 km) from Cape Cod Children's Museum. Island ...…

4.4/5Wonderful! (190 reviews)

"Very upscale community and right at the beach. Had to figure a lot out on your own and after having our dinner plans cancelled twice by the restaurant we really did not get any consideration - sorry we have to cancel. Did not feel real welcomed but like we were in someone else's territory."…"

Reviewed on Sep 16, 2020

The Club at New Seabury
The Cove at Yarmouth, a VRI resort
The Cove at Yarmouth, a VRI resort
3.5 out of 5
183 Main Street, West Yarmouth, MA
The price is $89 per night from Jan 25 to Jan 26

Situated near the beach, this aparthotel is 0.3 mi (0.5 km) from Putter's Paradise Miniature Golf and 1.5 mi (2.4 km) from Hyannis Harbor. Wild Animal Lagoon ...…

4.5/5Wonderful! (150 reviews)

"Place was very clean. Pool was nice. Staff was very friendly and helpful."…"

Reviewed on Oct 23, 2020

The Cove at Yarmouth, a VRI resort
Cape Winds Resort, a VRI resort
Cape Winds Resort, a VRI resort
3.5 out of 5
657 W Main Street, Hyannis, MA

Located in the heart of Hyannis, this condo resort is within 2 mi (3 km) of Cape Cod Melody Tent, Craigville Beach, and St. Francis Xavier Church. John F. Kennedy ...…

4.3/5Excellent! (234 reviews)

"The property host, Brian, was friendly and kind and very informative, a pleasure to communicate with. This made the stay more enjoyable."…"

Reviewed on Nov 25, 2020

Cape Winds Resort, a VRI resort
See all properties in Main Street Hyannis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit in Main Street Hyannis

Image for John F. Kennedy Hyannis Museum

John F. Kennedy Hyannis Museum

4.5/5(137 reviews)

Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.

John F. Kennedy Hyannis Museum
Image for Hyannis Harbor

Hyannis Harbor

4.5/5(591 reviews)

See the Cape Cod peninsula from a different perspective by riding a boat out of this picturesque harbor or wandering along its docks and jetties.

Hyannis Harbor
Image for Old Silver Beach

Old Silver Beach

4.5/5(171 reviews)

Go for a swim in the surprisingly warm water or enjoy the views across Buzzard Bay at Falmouth’s family-favorite beach.

Old Silver Beach
Image for Nauset Beach

Nauset Beach

4.5/5(208 reviews)

Vast expanses of white sand, light blue water and gentle waves mingle with the sounds of seabirds and seals at this secret gem in Cape Cod.

Nauset Beach
Image for West Dennis Beach

West Dennis Beach

4.5/5(175 reviews)

One of the most popular beaches in Dennis, this part of Cape Cod is vast and has the perfect weather for a range of land-based and offshore activities. 

West Dennis Beach
Image for Seagull Beach

Seagull Beach

4.5/5(4 reviews)

Take part in exhilarating watersports or relax on the sparkling sands of this sweeping beach.

Seagull Beach

Top things to do in Main Street Hyannis

Image for Ultimate Self-Driving Tour of Cape Cod and Provincetown

Ultimate Self-Driving Tour of Cape Cod and Provincetown

$10
Per adult
Ultimate Self-Driving Tour of Cape Cod and Provincetown
Image for 1-Day Boston+Cap Cod Tour (Boston departure) BC1

1-Day Boston+Cap Cod Tour (Boston departure) BC1

$65
Per adult
1-Day Boston+Cap Cod Tour (Boston departure) BC1
Image for Wine and Wine Jelly-Sauce Tasting on Plymouth Bay

Wine and Wine Jelly-Sauce Tasting on Plymouth Bay

$7
Per adult
100% of travellers recommend
Wine and Wine Jelly-Sauce Tasting on Plymouth Bay
Image for The Anne Hutchinson Tour of Provincetown

The Anne Hutchinson Tour of Provincetown

$19
Per adult
The Anne Hutchinson Tour of Provincetown
Image for 12:00 pm Timed-Entry Visit to New Bedford Whaling Museum

12:00 pm Timed-Entry Visit to New Bedford Whaling Museum

$19
Per adult
12:00 pm Timed-Entry Visit to New Bedford Whaling Museum
Image for 10:00 am Timed-Entry Visit to New Bedford Whaling Museum

10:00 am Timed-Entry Visit to New Bedford Whaling Museum

$19
Per adult
10:00 am Timed-Entry Visit to New Bedford Whaling Museum
See all activities in Main Street Hyannis

Cities near Main Street Hyannis

Hyannis showing a marina and a bay or harbor

Hyannis

Cape Cod

West Yarmouth

Hyannis Port

Hyannis Port