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Discover Northwest hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Kahler Grand Hotel

3.0 star property
Downtown Rochester, 5.3 mi from Northwest
8.4 out of 10, Very Good, (1799)
"Did know about a breakfast included in our room fee. "
United States
James
$149 nightly
The price is $172
Dec 11 - Dec 12
Total with taxes and fees
Kahler Grand Hotel

AmericInn by Wyndham Rochester Near Mayo Clinic

3.0 star property
6.7 mi from Northwest
8.2 out of 10, Very Good, (1125)
"Great location and value"
United States
Michelle
$73 nightly
The price is $84
Dec 12 - Dec 13
Total with taxes and fees
AmericInn by Wyndham Rochester Near Mayo Clinic

Econo Lodge Mayo Clinic Area

2.0 star property
7 mi from Northwest
9.0 out of 10, Wonderful, (890)
"Good breakfast..shuttle service is excellent..super nice staff.."
United States
DALE K
$63 nightly
The price is $72
Dec 22 - Dec 23
Total with taxes and fees
Econo Lodge Mayo Clinic Area

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3.0 star property
9.4 mi from Northwest
7.2 out of 10, Good, (1017)
"Breakfast was good. The staff was great. "
United States
Kjirsta
$72 nightly
The price is $83
Dec 9 - Dec 10
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4.0 star property
Kutzky Park, 5 mi from Northwest
9.4 out of 10, Exceptional, (950)
"Hotel was spotless, excellent staff and the breakfast was excellent. Late night eats at the restaurant and the food served was fantastic."
United States
Carmino
$111 nightly
The price is $127
Dec 26 - Dec 27
Total with taxes and fees
EVEN Hotel Rochester - Mayo Clinic Area by IHG

Aspen Suites

3.0 star property
5 mi from Northwest
9.0 out of 10, Wonderful, (686)
"I always stay at this hotel , love it clean comfortable rooms, they gave us vouchers for 4 free meals for Thanksgiving dinner"
United States
Cindy
$137 nightly
The price is $158
Dec 12 - Dec 13
Total with taxes and fees
Aspen Suites

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 star property
Downtown Rochester, 5.5 mi from Northwest
8.8 out of 10, Excellent, (881)
"Great room and stay!"
United States
Trevor
$67 nightly
The price is $77
Jan 1 - Jan 2, 2026
Total with taxes and fees
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

2.0 star property
1.7 mi from Northwest
7.8 out of 10, Good, (1002)
"Front staff are so kind and efficient. "
United States
Brenda
$64 nightly
The price is $73
Dec 12 - Dec 13
Total with taxes and fees
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Residence Inn by Marriott Rochester Mayo Clinic Area South

3.0 star property
6.4 mi from Northwest
9.6 out of 10, Exceptional, (242)
"Really nice property with a great staff and phenomenal outdoor seating area with fire pit and grill"
United States
Dwight
$115 nightly
The price is $133
Dec 14 - Dec 15
Total with taxes and fees
Residence Inn by Marriott Rochester Mayo Clinic Area South

Spark by Hilton Rochester South

3.0 star property
9.3 mi from Northwest
9.4 out of 10, Exceptional, (301)
"The rooms are very nice and the staff is very friendly "
United States
Roberta
$69 nightly
The price is $79
Dec 14 - Dec 15
Total with taxes and fees
Spark by Hilton Rochester South

Super 8 by Wyndham Rochester Mayo Clinic Area

2.0 star property
7.3 mi from Northwest
7.8 out of 10, Good, (1004)
"Great Stay"
United States
Aweng
$51 nightly
The price is $59
Dec 14 - Dec 15
Total with taxes and fees
Super 8 by Wyndham Rochester Mayo Clinic Area

Country Inn & Suites Rochester South Mayo Clinic

3.0 star property
8.5 mi from Northwest
8.4 out of 10, Very Good, (1003)
"Clean room, fun staff."
United States
Thomas
$97 nightly
The price is $112
Dec 27 - Dec 28
Total with taxes and fees
Country Inn & Suites Rochester South Mayo Clinic

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

3.0 star property
Kutzky Park, 5 mi from Northwest
8.6 out of 10, Excellent, (929)
"This is a convenient place to stay when visiting Mayo."
United States
Faith
$94 nightly
The price is $108
Dec 19 - Dec 20
Total with taxes and fees
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Hilton Rochester Mayo Clinic Area

3.5 star property
Downtown Rochester, 5.3 mi from Northwest
9.6 out of 10, Exceptional, (540)
"Had a great stay. Room was very clean and staff was very courteous. "
United States
Bonita
$171 nightly
The price is $197
Dec 13 - Dec 14
Total with taxes and fees
Hilton Rochester Mayo Clinic Area

MainStay Suites Rochester South Mayo Clinic

2.5 star property
8.4 mi from Northwest
7.0 out of 10, Good, (89)
"Staff is friendly "
United States
Merry
$56 nightly
The price is $64
Dec 9 - Dec 10
Total with taxes and fees
MainStay Suites Rochester South Mayo Clinic

Aspen Select

3.5 star property
5 mi from Northwest
8.4 out of 10, Very Good, (1002)
"Front desk staff was amazing, room was clean and the bed was comfortable! Location was perfect for us, right across the street from the hospital. Will definitely stay again, if the need arises! "
United States
Dana
$131 nightly
The price is $151
Dec 7 - Dec 8
Total with taxes and fees
Aspen Select

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 star property
6.1 mi from Northwest
8.2 out of 10, Very Good, (781)
"Great place to stay. Freindly staff"
United States
joel
$94 nightly
The price is $108
Dec 11 - Dec 12
Total with taxes and fees
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Baymont by Wyndham Rochester Mayo Clinic Area

2.5 star property
6.4 mi from Northwest
7.2 out of 10, Good, (716)
"Spotless clean"
United States
Brit
$60 nightly
The price is $69
Dec 14 - Dec 15
Total with taxes and fees
Baymont by Wyndham Rochester Mayo Clinic Area

Marriott Rochester Mayo Clinic

3.5 star property
Downtown Rochester, 5.4 mi from Northwest
8.2 out of 10, Very Good, (520)
"All staff were very nice and friendly and willing to help with whatever we needed. "
United States
Becky
$169 nightly
The price is $195
Dec 12 - Dec 13
Total with taxes and fees
Marriott Rochester Mayo Clinic

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3.0 star property
Historic Southwest, 5.6 mi from Northwest
8.6 out of 10, Excellent, (1002)
"The room was clean, the staff was very friendly and helpful."
United States
kenneth
$123 nightly
The price is $142
Dec 11 - Dec 12
Total with taxes and fees
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Northwest

Find the best Northwest areas and neighborhoods for the activities you enjoy most.

Downtown Rochester

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Civic Theater are top sights worth seeing.

Kutzky Park

While there might not be top attractions in Kutzky Park, you can explore the larger area and discover places like Soldiers Field Veterans Memorial and Mayo Civic Center.

Historic Southwest

While visiting Historic Southwest, you might make a stop by sights like Soldiers Field Veterans Memorial and Plummer House.

Slatterly Park

Slatterly Park might not have many top sights, but Rochester Art Center and Soldiers Field Veterans Memorial are two attractions nearby that you can check out.

East Side Pioneers

If you're spending some time in East Side Pioneers, Rochester Art Center and Rochester Civic Theater are top sights worth seeing.

Top Northwest Hotel Reviews

Frequently asked questions

What is Northwest like?
Travelers to Rochester's Northwest neighborhood will be sure to enjoy a stay in this neighborhood.
If I need to cancel my hotel reservation in Northwest, will I receive a refund?
Yes! Most hotel bookings are refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to view the best deals available in Northwest.
Where can I learn more about changing or cancelling my trip to Northwest?
To find more details about picking new dates or cancelling your trip to Northwest, go to https://www.expedia.com/service/.
What can I see and do in this Rochester neighborhood?
Places you might want to visit in the area around Northwest include Northern Hills Golf Course and Douglas State Trail Head Rochester. Make a stop at Assisi Heights and Rochester Recreation Center while you're sightseeing around the area.