Southern Illinois Vacations from $226

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Your Southern Illinois Vacation

When adventure is calling, answer it with a vacation package to Southern Illinois. Well known for its culture and history, this is one destination you'll never forget. Start your trip to Southern Illinois with a few nights in O'Fallon visiting popular sights like O'Fallon Family Sports Park and FanDuel Sportsbook and Horse Racing. Effingham is another city that draws travelers from far and wide. Lake Sara and Effingham Performance Center are two of the leading places to see in this destination. Quit dreaming and get packing, because your Southern Illinois vacation is just clicks away with Expedia.

The Latest Southern Illinois vacation packages

Price found within the past 48 hours. Click for updated prices.
Holiday Inn Express & Suites St. Louis West - Fenton by IHG
The Wildwood Hotel
The Principal Hotel
Hilton Garden Inn Chesterfield
Home2 Suites by Hilton St. Louis Downtown
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Where to stay in Southern Illinois

Find the best Southern Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southern Illinois

Discover the most popular places to visit in Southern Illinois

Southern Illinois Hotel Deals

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3 out of 5
145 North 44th Street , Mount Vernon, IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Aug 31 to Sep 1
$106 total
Aug 31 - Sep 1
Total includes taxes and fees
9.6/10 Exceptional! (1,410 reviews)
"Cannot think what would make it better; maybe a more refined dinner cuisine."

Reviewed on Aug 9, 2025

Drury Plaza Hotel Mt. Vernon
Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach

2.5 out of 5
1240 E Chain Of Rocks Rd, Granite City, IL
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $71 total per night from Aug 12 to Aug 13
$71 total
Aug 12 - Aug 13
Total includes taxes and fees
7.8/10 Good! (482 reviews)
"Nice staff, quiet hotel, rooms are dated and very minimal. No complaints, just very minimal."

Reviewed on Aug 9, 2025

Red Lion Inn & Suites Pontoon Beach
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

3 out of 5
12 Ludwig Dr, Fairview Heights, IL
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $106 total per night from Aug 17 to Aug 18
$106 total
Aug 17 - Aug 18
Total includes taxes and fees
9/10 Wonderful! (1,004 reviews)
"Breakfast buffet was really nice, free drinks until 9 was a nice surprise and the room was extremely comfortable and clean and quiet."

Reviewed on Aug 8, 2025

Drury Inn & Suites St. Louis Fairview Heights
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Things to do near Southern Illinois

Southern Illinois is perfect for outdoor enthusiasts seeking adventure and stunning scenery. Enjoy thrilling ziplines, wine tastings at local vineyards, and beautiful trails that cater to all hiking levels. With numerous recreational areas and campgrounds, you can immerse yourself in nature while experiencing the excitement of intensive hikes and outdoor activities. Whether you're exploring or relaxing, Southern Illinois offers unforgettable experiences for every adventurer.

Shopping

King City Square Shopping Center, located 5 miles from Southern Illinois, offers a vibrant shopping experience with a mix of entertainment and family-friendly activities. Explore various stores for unique gifts and souvenirs while enjoying the lively atmosphere of this local hotspot.

Recreation

The Benton Civic Center offers an enriching cultural experience with theater performances, perfect for family entertainment and romance. Lincoln Park provides a serene environment for relaxation and wellness activities, while Waltonville Public Use Area invites you to unwind amidst nature's beauty and enjoy recreational pursuits.

Adventure

The I-57 Drag Strip, located 23 miles from Southern Illinois, offers an exhilarating motor racing experience. Feel the adrenaline rush as you watch high-speed races or participate in drag racing events, surrounded by a lively atmosphere filled with sports and adventure vibes.

Nightlife

Southern Illinois boasts a vibrant nightlife with options like the lively Hangar 9 in Carbondale, perfect for live music, and the cozy ambiance of the Blue Sky Vineyard for a relaxing evening. Don’t miss the local bars in Murphysboro for a true taste of the area’s hospitality.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Southern Illinois

Southern Illinois is perfect for outdoor enthusiasts and adventure seekers, offering stunning scenery and numerous attractions. Explore beautiful lakes, national and state parks, and vibrant college campuses. Whether you're looking for a beach experience or a place to hike, Southern Illinois has a variety of points of interest that cater to all your outdoor desires, making it an ideal vacation destination for travelers seeking nature and adventure.

  • Jefferson County Fairgrounds: Experience the vibrant atmosphere of the Jefferson County Fairgrounds, just 3 miles from Southern Illinois. It's a family-friendly venue hosting various events and fairs, making it a great spot for outdoor fun and community engagement.
  • Rend Lake: About 13 miles away, Rend Lake offers breathtaking scenery and a picturesque beach. Perfect for romantic getaways or family outings, you can enjoy water activities, picnics, and stunning sunsets in a serene outdoor setting.
  • Veterans Memorial Park: Located 4 miles from Southern Illinois, Veterans Memorial Park is a place of reflection and culture. Pay tribute to veterans while enjoying peaceful walks through beautifully landscaped grounds, making it a meaningful stop on your journey.

Best time to go to Southern Illinois

The best time to visit Southern Illinois is dependant on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January30.9°F (-0.6000000000000001°C)Light RainMostlySlightly LowSlightly Low
February36.9°F (2.7°C)Light RainMostlySlightly LowSlightly Low
March48.0°F (8.9°C)Light RainMostly SunnyAverageAverage
April55.2°F (12.9°C)Light RainMostly SunnyAverageSlightly High
May66.7°F (19.3°C)Light RainMostly SunnySlightly HighAverage
June75.9°F (24.4°C)Light RainMostly SunnySlightly HighSlightly High
July78.8°F (26.0°C)Light RainMostly SunnySlightly HighSlightly High
August77.0°F (25.0°C)Light RainMostly SunnyAverageAverage
September71.2°F (21.8°C)Light RainMostly SunnyAverageAverage
October56.7°F (13.7°C)Light RainMostly SunnyAverageAverage
November46.6°F (8.1°C)Light RainMostly SunnyAverageSlightly Low
December39.0°F (3.9°C)Light RainMostly SunnySlightly LowAverage

Tips to save on your trip to Southern Illinois

  • Take advantage of package deals on Expedia and combine flights, hotels, or car rentals for a convenient and cost-effective trip to Southern Illinois.
  • Consider traveling during the off-peak season (typically January to February and November) for more affordable package holidays to Southern Illinois.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.