Penrose, MO

St. Louis


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Penrose Hotel Deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
$95 nightly
The price is $111 total per night from Dec 7 to Dec 8
$111 total
Dec 7 - Dec 8
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (2,987 reviews)
Nice hotel for the price

Reviewed on Nov 13, 2025

Clayton Plaza Hotel & Extended Stay
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
$101 nightly
The price is $120 total per night from Nov 23 to Nov 24
$120 total
Nov 23 - Nov 24
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,092 reviews)
Room was very clean, common areas could use new carpet. The hotel staff was extremely helpful and friendly. Parking was HIGH!! $57/per night after tax and before tip. Hotel felt very old European. This survey asked me about the ‘free breakfast’….that is the first Ive heard of a ‘free breakfast’. ...

Reviewed on Nov 12, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
$90 nightly
The price is $106 total per night from Nov 23 to Nov 24
$106 total
Nov 23 - Nov 24
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (2,742 reviews)
Shuttle to airport was great and then shuttle back to pick up my car was also great. Nice to be able to park at the property for a few days.

Reviewed on Nov 12, 2025

Pear Tree Inn St. Louis Airport
Forest Park Hotel by MDR

Forest Park Hotel by MDR

3 out of 5
5915 Wilson Ave St. Louis MO
$93 nightly
The price is $109 total per night from Nov 23 to Nov 24
$109 total
Nov 23 - Nov 24
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
7.4/10 Good! (1,216 reviews)
I arrived at almost 4 am after a long day at the hospital—my mom had surgery, & I just needed a few hours of real rest before heading back. Hotels.com and the front desk staff made it super easy to check in way before the normal 3 p.m. time, no hassle at all. The room was spotless, bed was so comfortable, ...

Reviewed on Nov 7, 2025

Forest Park Hotel by MDR
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
$144 nightly
The price is $168 total per night from Nov 21 to Nov 22
$168 total
Nov 21 - Nov 22
Total with taxes and fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (3,234 reviews)
Good variety of breakfast, room was clean ac working

Reviewed on Nov 10, 2025

Drury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
$109 nightly
The price is $129 total per night from Dec 12 to Dec 13
$129 total
Dec 12 - Dec 13
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (3,997 reviews)
Everything was great except the delay of the elevators. I believe half of them were working and the hotel was very busy. After checkin I waited at least 15 minutes for an elevator to get to my room.

Reviewed on Nov 10, 2025

Hyatt Regency St. Louis at The Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Penrose

Central West End

Central West End

4.5/5(450 area reviews)

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Central West End
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Midtown

While you're in Midtown, take in top sights like Chaifetz Arena and jump on the metro at Grand Station to see more of the city.

Midtown
Not just bars but also loft apartments are lit in rainbow lights for Pride weekend in the Grove neighborhood in St. Louis! #LifeAtExpedia

The Grove

The Grove might not have many top sights, but St. Louis Science Center and Missouri Botanical Gardens and Arboretum are two attractions nearby that you can check out.

The Grove
St. Louis which includes interior views

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Downtown West
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The Gate

While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Busch Stadium.

The Gate
Lafayette Square which includes a house and a garden

Lafayette Square

The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Busch Stadium, a few notable attractions nearby.

Lafayette Square


Penrose, MO

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