St. Charles Historic District, MO

St. Louis

trestle on Katy Trail in Missouri over Auxvasse Creek near Mokane - 237 mile bike trail stretching across most of the state of Missouri converted from abandoned railroad
St. Charles Historic District
St. Charles Historic District
St. Charles Historic District
St. Charles Historic District

Popular places to visit

Things to do


St. Charles Historic District Hotel Deals

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 out of 5
1190 S Main St St. Charles MO
$130 nightly
The price is $149 total per night from May 3 to May 4
$149 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,011 reviews)
Great room layouts. Open breakfast was super as well. Parking was difficult at times due to it being shared with neighbor restaurants.

Reviewed on Apr 20, 2026

Country Inn & Suites by Radisson, St. Charles Historic District
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
$100 nightly
The price is $116 total per night from May 3 to May 4
$116 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (3,161 reviews)
Breakfast was great especially with a toddler. The parking was also very convenient and fair! Room is slightly dated but the bathrooms have been renovated. Good place to rest your head and explore the rest of the city.

Reviewed on Apr 21, 2026

Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
$90 nightly
The price is $106 total per night from May 3 to May 4
$106 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (2,936 reviews)
Great breakfast and easy to get to the airport.

Reviewed on Apr 21, 2026

Pear Tree Inn St. Louis Airport
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
$156 nightly
The price is $183 total per night from May 3 to May 4
$183 total
May 3 - May 4
Total with taxes and fees
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (1,777 reviews)
Loved this hotel. Staff was amazing. Happy hour and food was very good. Only issue is that there is not much to do directly around hnotel...only a short walk to restaurants and hockey arena..so not awful.. Staff was so nice and hotel is very cool.

Reviewed on Apr 21, 2026

21C Museum Hotel St Louis
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $103 total per night from May 17 to May 18
$103 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,228 reviews)
The room was clean and in good shape. The breakfast was pretty good. The indoor pool and jacuzzi was clean and well maintained. Would definitely stay here again in a future visit

Reviewed on Apr 20, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
$159 nightly
The price is $189 total per night from May 10 to May 11
$189 total
May 10 - May 11
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
9.4/10 Exceptional! (1,165 reviews)
Perfectly located

Reviewed on Apr 20, 2026

Live by Loews - St.Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around St. Charles Historic District

St. Louis

Berkeley

Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

Berkeley
Creve Coeur Lake, Saint Louis, Missouri
Fall Season

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Creve Coeur
University City

University City

Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Museum of Transportation and Heman Park Tennis Center are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.

University City
View of St. Louis and the historic Gateway Arch in Missouri, from across the Mississippi River in Malcolm W. Martin Memorial Park, Illinois

Ladue

The restaurants and churches are a few reasons travelers visit Ladue. Though there aren't many top sights in the neighborhood, you can visit Saint Louis Galleria Mall and St. Louis Zoo, a few notable attractions nearby.

Ladue
St. Louis Missouri

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Clayton
The bandstand located in Forest Park, St. Louis, Missouri.

Dogtown

If you're looking for some top things to see and do in Dogtown and surrounding area, you can visit St. Louis Zoo and St. Louis Art Museum.

Dogtown


St. Charles Historic District, MO

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