A large eye sculpture in a park surrounded by trees.

Northeast Missouri Vacation Rentals

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Check prices for these dates

In two weeks
Oct 23 - Oct 25
In two months
Dec 4 - Dec 6
In three months
Jan 1 - Jan 3
In four months
Jan 29 - Jan 31

Our top choices for Northeast Missouri vacation rentals

A wooden-paneled room with a bed, a nightstand, a wall-mounted mirror, and a small shelf with decorative items.

1. Tiny Cozy Cottage in Edina, MO

Tiny Cozy Cottage in Edina, MO
Edina
10.0 out of 10, Exceptional, (21 reviews)
"Very nice place , clean and easy ."
United States
John
$97 nightly
The price is $103
Oct 12 - Oct 13
Total with taxes and fees
Tiny Cozy Cottage in Edina, MO
A park with a pond, picnic tables, and a gazebo.

2. Cannon Dam Cabins

Cannon Dam Cabins
3.0 star property
Perry
9.4 out of 10, Exceptional, (24 reviews)
"Amazing place to stay! You can’t beat the indoor pool whether it is storming or feels like the fires from hell are raining on earth you can still enjoy a great swim without worrying about lightning or burning to death. The people are incredibly kind and on top of anything you may need and the cabins are a perfect relaxing get away with nice a/c and plenty of sleeping space! Thank you for another amazing stay!"
United States
Erika
$103 nightly
The price is $109
Oct 12 - Oct 13
Total with taxes and fees
Cannon Dam Cabins
Private kitchen

3. The Cottage

The Cottage
2.0 star property
Hermann
10.0 out of 10, Exceptional, (1 review)
"Our host mentioned he does not receive messages from Expedia postings. So if you are not receiving check-in information, you might want to find another way to contact them. The property is lovely. The Treehouse was perfect for my granddaughter and me."
United States
Linda
$217 nightly
The price is $250
Oct 13 - Oct 14
Total with taxes and fees
The Cottage
A covered porch with wooden chairs and a small wooden table, a clock, and a view of a green landscape.

4. Lake Cabin near the Bourbeuse River

Lake Cabin near the Bourbeuse River
Leslie
10.0 out of 10, Exceptional, (59 reviews)
"It was a beautiful location that was quiet and very relaxing. It had all the amenities of a home. The perfect place to recharge for a while."
United States
Lynnette
$143 nightly
The price is $152
Oct 12 - Oct 13
Total with taxes and fees
Lake Cabin near the Bourbeuse River
A modern kitchen with stainless steel appliances, a stone accent wall, and a bar area.

5. Aunt Lele's Cozy Cottage

Aunt Lele's Cozy Cottage
Quincy
9.8 out of 10, Exceptional, (46 reviews)
"Perfect place for our family of 5 to enjoy a weekend visiting my wife’s family."
United States
Matt B.
$138 nightly
The price is $157
Oct 18 - Oct 19
Total with taxes and fees
Aunt Lele's Cozy Cottage
A wooden building with a dark door and a porch area.

6. Teal Nest - at The Lodges of Long Branch

Teal Nest - at The Lodges of Long Branch
Bevier Township
10.0 out of 10, Exceptional, (9 reviews)
"Great place to stay and relax. Great Italian Food close by -Ugo;s. Will stay here again next year"
United States
Vincent H.
$185 nightly
The price is $190
Oct 15 - Oct 16
Total with taxes and fees
Teal Nest - at The Lodges of Long Branch
A compact living space with a sofa, a TV, a kitchen area with a fridge, microwave, and coffee maker, and a dining table.

7. The Mercantile on the Katy Trail

The Mercantile on the Katy Trail
4.5 star property
Hermann
9.8 out of 10, Exceptional, (40 reviews)
"This is just simply a really neat place to stay while biking the Katy. Suites are spacious and very well appointed even to washers and laundry soap to clean your duds after a dusty day on the trail"
United States
James
$195 nightly
The price is $210
Oct 27 - Oct 28
Total with taxes and fees
The Mercantile on the Katy Trail
A building with a glass door marked "108" and a sign for "Web Print Radio Television Public Relations."

8. The Library, 1-queen bed, 1-bedroom apartment in Hannibal awaits your visit.

The Library, 1-queen bed, 1-bedroom apartment in Hannibal awaits your visit.
Hannibal
9.8 out of 10, Exceptional, (17 reviews)
"We had a great stay here. It was much larger than expected with a sitting room, bedroom, bath, kitchen and laundry area. In the heart of all in town and yet very safe."
United States
Dan R.
$125 nightly
The price is $135
Oct 26 - Oct 27
Total with taxes and fees
The Library, 1-queen bed, 1-bedroom apartment in Hannibal awaits your visit.
A modern kitchen with white cabinets, stainless steel appliances, and a wooden floor.

9. Spacious & Modern 2BR Home with Attached Garage

Spacious & Modern 2BR Home with Attached Garage
Quincy
10.0 out of 10, Exceptional, (54 reviews)
"Nicely decorated and very comfortable."
United States
Marsha
$190 nightly
The price is $217
Oct 19 - Oct 20
Total with taxes and fees
Spacious & Modern 2BR Home with Attached Garage
A living room with a brown sofa, a wooden coffee table, a television on a stand, and a bookshelf.

10. Unwind on Vine

Unwind on Vine
Macon
9.6 out of 10, Exceptional, (38 reviews)
"We have stayed twice at Unwind on the Vine and have enjoyed our stays. The owners are very attentive to any needs we have had during our stays."
United States
Nancy E.
$225 nightly
The price is $242
Oct 13 - Oct 14
Total with taxes and fees
Unwind on Vine
A room with a brick wall, shelves with plants, a framed painting, and a patterned bench.

11. Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
Hannibal
9.8 out of 10, Exceptional, (68 reviews)
"Great location for downtown exploring."
United States
Lisa B.
$175 nightly
The price is $189
Oct 20 - Oct 21
Total with taxes and fees
Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
A modern kitchen with white cabinets, a stainless steel refrigerator, and a dining area with a wooden table and white chairs.

12. Peaceful, Country Cottage with Open Floor Plan

Peaceful, Country Cottage with Open Floor Plan
Quincy
9.8 out of 10, Exceptional, (225 reviews)
"Only there for a one night stay, but very beautiful and comfortable!"
United States
Vicki W.
$233 nightly
The price is $247
Oct 13 - Oct 14
Total with taxes and fees
Peaceful, Country Cottage with Open Floor Plan
A rustic bar area with stone walls, wooden chairs, and hanging pendant lights.

13. Studio Condo on the Water @ Innsbrook

Studio Condo on the Water @ Innsbrook
Wright City
10.0 out of 10, Exceptional, (71 reviews)
"everything was clean and really beautiful, we enjoyed the stay "
United States
Vanessa O.
$179 nightly
The price is $191
Oct 13 - Oct 14
Total with taxes and fees
Studio Condo on the Water @ Innsbrook
A spacious living area with a dining table, sofa, and a large window with blinds.

14. Stunning Minimalist Gem | Fenced Backyard + W/D

Stunning Minimalist Gem | Fenced Backyard + W/D
Princeton Heights
9.8 out of 10, Exceptional, (29 reviews)
"Nice area, very well kept house and easy check-in process. Good parking"
United States
Christopher
$151 nightly
The price is $177
Oct 18 - Oct 19
Total with taxes and fees
Stunning Minimalist Gem | Fenced Backyard + W/D
A cozy living room with a brown leather couch, a wooden spiral staircase, and large windows offering a view of the outdoors.

15. The Nest, unplug& reconnect with that special someone in our charming birdhouse!

The Nest, unplug& reconnect with that special someone in our charming birdhouse!
Troy
9.4 out of 10, Exceptional, (55 reviews)
"The property was amazing perfect for a couple or a individual how wants to unplug."
United States
Jess H.
$195 nightly
The price is $208
Oct 13 - Oct 14
Total with taxes and fees
The Nest, unplug& reconnect with that special someone in our charming birdhouse!
A spacious foyer with a grand staircase, a piano, and a large rug.

16. White House at Grand Central

White House at Grand Central
3.5 star property
Grand Center
8.2 out of 10, Very good, (163 reviews)
"Nice find in the city"
United States
Mark
$134 nightly
The price is $151
Oct 13 - Oct 14
Total with taxes and fees
White House at Grand Central
A cozy living room with a wooden staircase, a chessboard on a round table, and a lamp on a side table.

17. The John Sydney House - Family and Pet Friendly Historic Home Downtown

The John Sydney House - Family and Pet Friendly Historic Home Downtown
Hannibal
9.6 out of 10, Exceptional, (27 reviews)
"Rooms were clean and the decor was very well done! We loved our stay here and the hosts were responsive to all our needs."
United States
Brian H.
$237 nightly
The price is $257
Oct 12 - Oct 13
Total with taxes and fees
The John Sydney House - Family and Pet Friendly Historic Home Downtown
A covered patio with string lights, a seating area, and a small table.

18. TJ’s Country Getaway- Dog Friendly

TJ’s Country Getaway- Dog Friendly
Union
10.0 out of 10, Exceptional, (52 reviews)
"Best solo stay VRBO I've experienced. Quaint location; immaculately maintained/clean; bedding and bathroom accommodations excellent; any and everything needed in kitchenette; good wifi and tv; etc... Special place for dog lovers. Nice host!"
United States
Kelly S.
$155 nightly
The price is $165
Oct 26 - Oct 27
Total with taxes and fees
TJ’s Country Getaway- Dog Friendly
Property grounds

19. Charming 2-bedroom house in nice Imperial with AC. Attn! Traveling Contractors

Charming 2-bedroom house in nice Imperial with AC. Attn! Traveling Contractors
Imperial
9.8 out of 10, Exceptional, (8 reviews)
"Thank you we enjoyed the place but we would like to get some more nights if all possible"
United States
Tommy H.
$110 nightly
The price is $116
Oct 13 - Oct 14
Total with taxes and fees
Charming 2-bedroom house in nice Imperial with AC. Attn! Traveling Contractors
A rooftop terrace with a brick wall, a metal railing, and a table with chairs.

20. Deck + River View: Loft in Downtown Hannibal

Deck + River View: Loft in Downtown Hannibal
3.0 star property
Hannibal
$230 nightly
The price is $265
Oct 15 - Oct 16
Total with taxes and fees
Deck + River View: Loft in Downtown Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Northeast Missouri Hotel Reviews

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"The staff was very helpful and nice. The food was very good as well."
Thomas 3-night trip
Posted less than an hour ago
Drury Plaza Hotel St. Louis Union Station

Find out more about Northeast Missouri

Everything you need to know about Northeast Missouri vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Northeast Missouri vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Northeast Missouri vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Northeast Missouri vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Northeast Missouri. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Northeast Missouri in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $70 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Northeast Missouri rentals

At Expedia, we put the best Northeast Missouri vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Northeast Missouri rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Northeast Missouri vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Northeast Missouri. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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