Northeast Missouri, MO
Travel Guide
Visit Northeast Missouri
Where to stay in Northeast Missouri
Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Soulard
You'll enjoy the bars and churches in Soulard. You might want to make time for a stop at Anheuser-Busch Brewery or Soulard Farmer's Market.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.
Berkeley
Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.
21C Museum Hotel St Louis
We loved this hotel. It is something you expect in much more sophisticated cities but not St. Louis. Our king bed suite was tastefully furnished and very large. Lots of great touches and very clean. The lobby and museum were stylish and exciting. We ate at both Idolwolf and the cafe. Again great ...
Reviewed on Feb 8, 2026
Clayton Plaza Hotel & Extended Stay
Friendly staff. Great breakfast. Location and parking convenient. Would stay again.
Reviewed on Feb 11, 2026
Pear Tree Inn St. Louis Airport
Great experience
Reviewed on Feb 11, 2026
White House at Grand Central
The rooms were FREEZING!!!!! staff is in a different building. they told me to “wait for it to warm up”…so I had to leave for hours…it never warmed past 66 degrees. So the next day they moved us to a different room, which was nice but that room was set at 50°. We saw a heater in the closet so we ...
Reviewed on Jan 26, 2026
Lighthouse Inn & Suites
Nice room. Matched the pictures. Exactly what we were looking for.
Reviewed on Jan 18, 2026
beautiful small house
Stay is accurate for the price. You get what you pay for. My only complaint was the strong odor of marijuana throughout the house when marketed as smoke-free. Would not suggest if you have asthma to stay here. The host communicated and partially refunded with the odor. Couldn’t beat the location ...
Reviewed on Jan 5, 2026
Check Northeast Missouri hotel availability
Popular places to visit
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
Washington University in St. Louis
Enjoy the collegiate vibe at Washington University in St. Louis during your stay in St. Louis. Amble around the area's lush forest or attend a sporting event.
Dome at America’s Center
Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's fascinating museums and great live music.
Things to do
Tom's Town Distillery Tour and Tasting
Small-Group Jewelry Making with Wine Tasting in Kansas City
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- St. Louis Union Station
- Busch Stadium
- Dome at America’s Center
- St. Louis Zoo
- Six Flags St. Louis
- Enterprise Center
- Washington University in St. Louis
- America's Center Convention Complex
- Barnes Jewish Hospital
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- Mississippi River
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- Route 66 State Park
- Historic Main Street
- Hollywood Casino
- Centene Community Ice Center
- Grant's Farm
- St. Louis Aquarium at Union Station
- Hidden Valley Ski Resort
