Title: Santa Prassede Tours - Book Now | Expedia.com [Santa Prassede Hotels](https://expedia.com/Santa-Prassede-Hotels.0-l6074128-0.Travel-Guide-Filter-Hotels)[Car Rentals in Santa Prassede](https://expedia.com/Car-Rentals-In-Santa-Prassede.d6074128.Car-Rental-Guide)[Rome City Centre Vacations](https://expedia.com/Rome-City-Centre.d553248633938945217.Destination-Travel-Guides) # Santa Prassede Tours ![One of the oldest churches in Rome with wonderful mosaics!](https://images.trvl-media.com/place/3023/25d8f4ab-6317-4fe0-8013-5c9941628331.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![One of the oldest churches in Rome with wonderful mosaics!](https://images.trvl-media.com/place/3023/25d8f4ab-6317-4fe0-8013-5c9941628331.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Great mosaic on the ceiling of the side chapel ](https://images.trvl-media.com/place/3023/8a9cca9a-d218-4b14-b840-08d5f3caa2af.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![View into the backyard ](https://images.trvl-media.com/place/3023/479309ca-8276-4a7a-9ff7-c532e86bdb33.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Another mosaic in a side chapel](https://images.trvl-media.com/place/3023/7ad148c6-bf9e-4e65-a487-fd6c44f03d57.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Santa Prassede Activities --- --- A house of worship for some, Santa Prassede is worth checking out, irrespective of your spiritual beliefs. Find out if this holy sanctuary is open to tourists for the perfect pause from your busy travel itinerary. This house of prayer is often on the itineraries of visitors to [Rome City Centre](https://www.expedia.com/Rome-Rome-City-Centre.dx553248633938945217). But Santa Prassede isn't the only highlight in the area. St. Peter's Basilica, Roman Forum, and Piazza Navona are some other recommended attractions close by. ## Plan a trip to see Santa Prassede Price found within the past 48 hours. Click for updated prices. ![Residenza Piranesi Boutique Hotel](https://images.trvl-media.com/lodging/100000000/99800000/99790400/99790372/c0bf2948_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Residenza Piranesi Boutique Hotel Rome City Centre Save 100% on your flight $1,911 per person Apr 14 - Apr 20 found 1 day ago Roundtrip flight included New York (NYC) to Rome (FCO) 9.4/10 Exceptional! (86 reviews) Good room and staff helpful . Reviewed on Nov 29, 2025 ![U-Visionary Roma Hotel](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/d2a3197d_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### U-Visionary Roma Hotel Rome City Centre Save 100% on your flight $2,345 per person May 10 - May 16 found 1 day ago Roundtrip flight included New York (JFK) to Rome (FCO) 9.6/10 Exceptional! (411 reviews) I was so disappointed with this hotel. It purports to be a 5 star hotel and I was certainly paying a rate commensurate with that but it simply isn’t of a high enough standard to deserve a 5 star rating. From staff arguing with each other in front of us to being denied entry to the bar because it was too busy; there simply isn’t enough room for me to list their faults here, which essentially come down to a lack of attention to detail and care but if the management want to write to me I will give them the full list. Reviewed on Jan 3, 2026 ![Palazzo Dama](https://images.trvl-media.com/lodging/14000000/13190000/13187600/13187549/f5a50c03_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Palazzo Dama Rome City Centre Save 100% on your flight $2,639 per person May 10 - May 16 found 1 day ago Roundtrip flight included New York (JFK) to Rome (FCO) 8.8/10 Excellent! (171 reviews) Wonderful stay at the Palazzo Dama for my husband’s 40th. We had a junior suite which was a good size, very comfortable and immaculate. Great location and friendly, professional staff. Lovely to stay in a boutique hotel with such unique features. Felt very luxe! Reviewed on Feb 15, 2026 ### Browse tours and tickets to explore Santa Prassede ### Tours & day trips [See all 1229 activities](https://expedia.com/things-to-do/search?&rid=6074128&location=Santa+Prassede&filter.categories=ToursDayTrips) ![Vatican Museums, Sistine Chapel, & St. Peter’s Basilica Fully Guided Tour](https://mediaim.expedia.com/localexpert/166597/4f9bb377-01c6-4b8f-980f-7747e7f07a85.jpg?impolicy=resizecrop&rw=500&rh=280) ### Vatican Museums, Sistine Chapel, & St. Peter’s Basilica Fully Guided Tour 2h+ 9/10 6,590 verified reviews Free cancellation available $84 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/vatican-museums-sistine-chapel-st-peters-basilica-fully-guided-tour.a166597.activity-details?&rid=6074128&location=Santa+Prassede&swp=off) ![Colosseum & Ancient Rome Guided Tour with Roman Forum & Palatine Hill](https://mediaim.expedia.com/localexpert/166587/4edbea50-914d-4144-a851-55e98d3e0a1f.jpg?impolicy=resizecrop&rw=500&rh=280) ### Colosseum 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Dinner](https://mediaim.expedia.com/localexpert/47875709/00ed299e-8a03-42a0-be5d-511dea604617.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: Italian Opera Concert and Traditional Dinner 2h 8/10 31 GetYourGuide reviews Free cancellation available $93 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/rome-italian-opera-concert-and-traditional-dinner.a47875709.activity-details?&rid=6074128&location=Santa+Prassede&swp=off) ![Rome: Candlelight Wine tasting in ancient roman Cave](https://mediaim.expedia.com/localexpert/50475009/72cf65bf-2b6e-45cb-8c04-3be2ba9ff764.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: Candlelight Wine tasting in ancient roman Cave 2h 30m Free cancellation available $134 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/rome-candlelight-wine-tasting-in-ancient-roman-cave.a50475009.activity-details?&rid=6074128&location=Santa+Prassede&swp=off) ![Rome: Opera Concert in Palazzo Doria Pamphilj](https://mediaim.expedia.com/localexpert/44531299/c8a5af80-8241-4fd2-a397-e6661435a0c3.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: Opera Concert in Palazzo Doria Pamphilj 1h 30m+ 8.4/10 7 GetYourGuide reviews Free cancellation available $115 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/rome-opera-concert-in-palazzo-doria-pamphilj.a44531299.activity-details?&rid=6074128&location=Santa+Prassede&swp=off) ![Villa d'Este Magic, Enchanting Photoshoot in Tivoli](https://mediaim.expedia.com/localexpert/49090543/2fe912d1-eb4c-46cd-99e8-a2b41fe3abad.jpg?impolicy=resizecrop&rw=500&rh=280) ### Villa d'Este Magic, Enchanting Photoshoot in Tivoli 1h Free cancellation available $232 includes taxes & fees per traveler\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.com/things-to-do/villa-deste-magic-enchanting-photoshoot-in-tivoli.a49090543.activity-details?&rid=6074128&location=Santa+Prassede&swp=off) ![Rome Pre-Post Cruise Transfer 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### Spa & wellness [See all 38 activities](https://expedia.com/things-to-do/search?&rid=6074128&location=Santa+Prassede&filter.categories=SpaWellness) ![Rome: QC Termeroma Spa Admission Ticket](https://mediaim.expedia.com/localexpert/48247399/4c53bbdc-c39a-45bb-946a-5f5b41643966.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: QC Termeroma Spa Admission Ticket 5h+ 10/10 2 GetYourGuide reviews Free cancellation available $81 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/rome-qc-termeroma-spa-admission-ticket.a48247399.activity-details?&rid=6074128&location=Santa+Prassede&swp=off) ![Rome: Fitness and Sightseeing Experience](https://mediaim.expedia.com/localexpert/50545888/c5ea0b0a-bd25-48ba-aeca-16f59e3080eb.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: Fitness and Sightseeing Experience 1h 30m Free cancellation available $34 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/rome-fitness-and-sightseeing-experience.a50545888.activity-details?&rid=6074128&location=Santa+Prassede&swp=off) ![Rome: Christian Landmarks Golf Cart Tour](https://mediaim.expedia.com/localexpert/51784196/38d87411-a3db-41e1-b70d-a8aa79e8ab4a.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: Christian Landmarks Golf Cart Tour 3h Free cancellation available $290 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.com/things-to-do/rome-christian-landmarks-golf-cart-tour.a51784196.activity-details?&rid=6074128&location=Santa+Prassede&swp=off) ![Rome: St. Paul Private Tour with Driver](https://mediaim.expedia.com/localexpert/51713187/037e7c3c-ea3e-46de-baf4-48a54e3ee82f.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: St. Paul Private Tour with Driver 3h Free cancellation available $116,102 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/rome-st-paul-private-tour-with-driver.a51713187.activity-details?&rid=6074128&location=Santa+Prassede&swp=off) ![Appian Way Aqueducts Extended E-Bike & Food Adventure -45kms](https://mediaim.expedia.com/localexpert/51948295/885c965f-5086-4f44-aed3-a51fb37a3a82.jpg?impolicy=resizecrop&rw=500&rh=280) ### Appian Way Aqueducts Extended E-Bike & Food Adventure -45kms 6h Free cancellation available $289 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.com/things-to-do/appian-way-aqueducts-extended-e-bike-food-adventure-45kms.a51948295.activity-details?&rid=6074128&location=Santa+Prassede&swp=off) ![Santa Maria Maggiore Basilica and Dome area Guided Tour](https://mediaim.expedia.com/localexpert/51905573/99c49e85-d0e1-4512-b61c-f51978d33bab.jpg?impolicy=resizecrop&rw=500&rh=280) ### Santa Maria Maggiore Basilica and Dome area Guided Tour 2h Free cancellation available $254 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/santa-maria-maggiore-basilica-and-dome-area-guided-tour.a51905573.activity-details?&rid=6074128&location=Santa+Prassede&swp=off) ![Vatican Scavi with St Peter's Tomb and skip line St. Peter's](https://mediaim.expedia.com/localexpert/51949531/6ed9481d-b63c-422a-b95c-51e3ae058a6d.jpg?impolicy=resizecrop&rw=500&rh=280) ### Vatican Scavi with St Peter's Tomb and skip line St. Peter's 2h 10/10 1 GetYourGuide review Free cancellation available $134 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/vatican-scavi-with-st-peters-tomb-and-skip-line-st-peters.a51949531.activity-details?&rid=6074128&location=Santa+Prassede&swp=off) ![Discover St. Peter's Basilica: Dome & Historical Walk](https://mediaim.expedia.com/localexpert/51943865/8827062c-7d4e-4c10-860a-23d757a345a5.jpg?impolicy=resizecrop&rw=500&rh=280) ### Discover St. Peter's Basilica: Dome & Historical Walk 2h Free cancellation available $110 includes taxes & fees per adult [](https://www.expedia.com/things-to-do/discover-st-peters-basilica-dome-historical-walk.a51943865.activity-details?&rid=6074128&location=Santa+Prassede&swp=off) ### Popular places to visit ![Piazza Santa Maria in Trastevere in Rome, Italy](https://images.trvl-media.com/place/6158757/6a9a67b6-ee19-42e4-920e-9802d2659cd2.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Piazza Santa Maria Maggiore Find out about the history of Rome when you take a trip to Piazza Santa Maria Maggiore. Experience the fascinating museums and acclaimed theater scene in this vibrant area. [](https://expedia.com/Piazza-Santa-Maria-Maggiore-Rome-City-Centre.d6158757.Vacation-Attraction) ![Italy, Rome, pigeons flying in front of Santa Maria Maggiore](https://images.trvl-media.com/place/6073994/3e171137-0b57-4432-875d-8acfddbf08f5.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Basilica di Santa Maria Maggiore Learn about the local history of Rome with a stop at Basilica di Santa Maria Maggiore. Visit the notable monuments and churches in this vibrant area. [](https://expedia.com/Basilica-Di-Santa-Maria-Maggiore-Rome-City-Centre.d6073994.Vacation-Attraction) ![Terme di Trajano](https://images.trvl-media.com/place/3023/daeb77c3-4958-4318-8838-fee400ca07df.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Baths of Trajan Find out about the history of Rome when you spend time at Baths of Trajan. Discover the acclaimed theater scene and notable monuments in this vibrant area. [](https://expedia.com/Baths-Of-Trajan-Rome-City-Centre.d6284520.Vacation-Attraction) #### Arch of Gallienus You can find out about the history of Rome with a trip to Arch of Gallienus. Experience the fascinating museums and acclaimed art scene in this vibrant area. [](https://expedia.com/Arch-Of-Gallienus-Rome-City-Centre.d866962935359340544.Vacation-Attraction) #### Villa Giustiniani Massimo Explore the great outdoors at Villa Giustiniani Massimo, a lovely green space in Rome. Discover the fascinating museums and churches in this vibrant area. [](https://expedia.com/Villa-Giustiniani-Massimo-Rome.d553248621532501679.Vacation-Attraction) #### Chiesa di San Martino ai Monti Chiesa di San Martino ai Monti is just one of the places to see in Rome, so why not enjoy the other things to explore during your travels? Experience the acclaimed art scene and fascinating museums in this vibrant area. [](https://expedia.com/Chiesa-Di-San-Martino-Ai-Monti-Rome-City-Centre.d553248621533001834.Vacation-Attraction) --- ## Best Lodging Options Near Santa Prassede ## Check availability on hotels close to Santa Prassede [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6074128&startDate=2026-03-04&endDate=2026-03-05)[Mar 4 - Mar 5](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6074128&startDate=2026-03-04&endDate=2026-03-05) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6074128&startDate=2026-03-05&endDate=2026-03-06)[Mar 5 - Mar 6](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6074128&startDate=2026-03-05&endDate=2026-03-06) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6074128&startDate=3%2F6%2F2026&endDate=3%2F8%2F2026)[Mar 6 - Mar 8](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6074128&startDate=3%2F6%2F2026&endDate=3%2F8%2F2026) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6074128&startDate=3%2F13%2F2026&endDate=3%2F15%2F2026)[Mar 13 - Mar 15](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6074128&startDate=3%2F13%2F2026&endDate=3%2F15%2F2026) ![Hotel Quirinale](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/df3b5a06_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Quirinale Via Nazionale 7 Rome RM [](https://expedia.com/Rome-Hotels-Hotel-Quirinale.h1058.Hotel-Information) ![UNA Hotels Decò Roma](https://images.trvl-media.com/lodging/3000000/2230000/2222500/2222425/f97ca989_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### UNA Hotels Decò Roma Via Giovanni Amendola, 57 Rome RM [](https://expedia.com/Rome-Hotels-UNAHOTELS-Deco-Roma.h2222425.Hotel-Information) ![Hotel Artemide](https://images.trvl-media.com/lodging/1000000/50000/45900/45856/dccbfa6d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Artemide Via Nazionale 22 Rome RM [](https://expedia.com/Rome-Hotels-Hotel-Artemide.h45856.Hotel-Information) ![The Hive Hotel](https://images.trvl-media.com/lodging/25000000/24470000/24463300/24463268/ec6c185a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Hive Hotel Via Torino 6 Rome RM [](https://expedia.com/Rome-Hotels-The-Hive-Hotel.h24463268.Hotel-Information) ![Best Western Plus Hotel Universo](https://images.trvl-media.com/lodging/1000000/30000/21200/21157/97641de1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Best Western Plus Hotel Universo Via Principe Amedeo 5/B Rome RM [](https://expedia.com/Rome-Hotels-Best-Western-Plus-Hotel-Universo.h21157.Hotel-Information) ![Domus Liberius](https://images.trvl-media.com/lodging/8000000/7520000/7519600/7519559/ec09ac3e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Domus Liberius Via Liberiana, 17 Rome RM [](https://expedia.com/Rome-Hotels-Domus-Liberius.h7519559.Hotel-Information) ![Augusta Lucilla Palace](https://images.trvl-media.com/lodging/3000000/2050000/2046400/2046331/5e7ee858_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Augusta Lucilla Palace Via Massimo d'Azeglio, 24 Rome RM [](https://expedia.com/Rome-Hotels-Augusta-Lucilla-Palace.h2046331.Hotel-Information) ![Gioberti Hotel](https://images.trvl-media.com/lodging/1000000/80000/70700/70681/432a0390_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Gioberti Hotel Via Gioberti, 20 Rome RM [](https://expedia.com/Rome-Hotels-Gioberti-Hotel.h70681.Hotel-Information) ![The Major](https://images.trvl-media.com/lodging/1000000/530000/527500/527479/8c6ffb5e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Major Via di Santa Maria Maggiore 143 Rome RM [](https://expedia.com/Rome-Hotels-The-Major.h527479.Hotel-Information) [See all 15,183 properties in Santa Prassede](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6074128) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. 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