Find 4 Star Hotels in Serra Mesa, CA from $105

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Compare Serra Mesa 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Serra Mesa.

Pendry San Diego

550 J Street, San Diego, CA

$293

$380 total

includes taxes & fees

Jul 11 - Jul 12

9.2/10 Wonderful! (1,003 reviews)

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 4-star hotels in Serra Mesa?

San Diego Marriott Mission Valley and DoubleTree by Hilton Hotel San Diego - Mission Valley are two top-rated escapes located in or near Serra Mesa. Both have a 4-star rating and offer high-end comfort alongside an unbeatable traveler experience. Book a stay at the first and make use of concierge services and premium bedding. The second has designer toiletries and a swimming pool, among many amenities.

How much does it cost to stay in a 4-star hotel in Serra Mesa?

Expedia can help you quickly track down the ideal 4-star hotel for your stay in Serra Mesa. Use our handy filter tool to tailor your search by things like price, amenities and property star rating and get access to fabulous deals in a few clicks.

Search for the lowest price from $284

What's the difference between 5-star and 4-star hotels in Serra Mesa?

If you choose to book a stay at a 4-star hotel in Serra Mesa, you’ll usually find plenty of amenities to ensure you’re relaxed, such as a pool, gym and restaurant. You can experience excellent service and upmarket surroundings. Go for a 5-star hotel and you’ll get a few extra bells and whistles — think on-site spas, concierge assistance and indulgent turndown services. You’re likely to get extra amenities and first-class services at a 5-star stay, but both are terrific options for luxury guests.

Does Serra Mesa have any 4-star all-inclusive resorts?

Our “All inclusive” filter makes it easy to search for your dream resort. You’ll also find other standard 4-star stays like DoubleTree by Hilton Hotel San Diego - Mission Valley and San Diego Marriott Mission Valley. Offering the same level of luxury and comfort, they are excellent options for your Serra Mesa getaway.

Are there any 4-star casino hotels in Serra Mesa?

Shuffle between your room and the roulette wheel with ease by using our filters to find 4-star casino hotels in and around Serra Mesa. Celebrating with somebody special? Refine your search further by choosing amenities with a wow-factor, like a pool or view.

What are the top 4-star apartments in Serra Mesa?

Expedia guests love stays like Lyric | San Diego Boutique Suites because they typically offer more space and privacy than a standard hotel. Select this or another of our 4-star properties in Serra Mesa and experience that home-away-from-home ambience during your escape.

Recent reviews of Serra Mesa hotels
Expedia verified reviews

5/5 Excellent

"Very nice friendly staff, very clean. "

A verified traveler stayed at Marriott Marquis San Diego Marina

Posted 13 hours ago

5/5 Excellent

great stay, very clean

"We had a fabulous time. The hotel is on the older side, but that did not affect the stay at all. The mattress was great. Multiple options of pillows. Room had fridge, safe, iron, and hair drier. We got a room with balcony bayside, beautiful views. Room was made up every day. Pool clean with towels available. Staff friendly and helpful, my son went up to our room with all keys while we were at the pool and the desk got me an extra one. Coffee cart was great. Wish they had a restaurant, but Claim Jumper shares space with them. Not my favorite restaurant but still good food. Only negative is that the bathrooms don't have vents, but the water was very hot, everything in working order and clean, so it didn't matter too much."

A verified traveler stayed at Wyndham San Diego Bayside

Posted 16 hours ago