Cheap Copa flights Panama City (PTY) to Guatemala City (GUA)

Landing cheap one-way Copa Airlines flights from PTY to GUA on Expedia is a cinch — just filter by "Price (lowest to highest)." Alternatively, check out our budget-friendly return fares for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for Copa Airlines flights from PTY to GUA about one month before you want to leave. The most affordable time to reserve an international flight is generally 18 to 29 days ahead of your travel date when you can save 17% versus booking four to five months in advance. No matter your itinerary and fare class, the best day of the week to book international airfare is usually Sunday. Friday can be the most expensive. Travelers booking on a Sunday can save an average of 17% compared to those who book on a Friday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Setting off from PTY at 7:27AM UTC-5, the first Copa Airlines flight to GUA arrives at 8:52AM UTC-6. Flying early means you're less likely to experience cancellations.* Don't like early starts? The last Copa Airlines flight from PTY to GUA departs at 9:21PM UTC-5 and touches down at 10:48PM UTC-6.*Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.