$396 Cheap Flights from Santo Domingo (SDQ) to Cusco (CUZ)

View $396 flight on Thu, Oct 30, 2025Opens in a new window

Popular airlines from Las Americas Intl. Airport (SDQ) to Alejandro Velasco Astete Intl. Airport (CUZ)

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Cheap Flights from Santo Domingo to Cusco (SDQ-CUZ)

Prices were available within the past 7 days and start at $396 for one-way flights and $783 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Thu, Oct 16 - Thu, Oct 23
SDQ
Santo Domingo
CUZ
Cusco
$783 Roundtrip, found 5 days ago
$783
Roundtrip
found 5 days ago
Select avianca flight, departing Thu, Oct 16 from Santo Domingo to Cusco, returning Thu, Oct 23, priced at $783 found 5 days ago
avianca
Mon, Mar 2 - Sat, Mar 14
SDQ
Santo Domingo
CUZ
Cusco
$785 Roundtrip, just found
$785
Roundtrip
just found
Select avianca flight, departing Mon, Mar 2 from Santo Domingo to Cusco, returning Sat, Mar 14, priced at $785 just found
avianca
Thu, Nov 13 - Thu, Nov 20
SDQ
Santo Domingo
CUZ
Cusco
$809 Roundtrip, found 3 days ago
$809
Roundtrip
found 3 days ago
Select avianca flight, departing Thu, Nov 13 from Santo Domingo to Cusco, returning Thu, Nov 20, priced at $809 found 3 days ago
avianca
Tue, Nov 4 - Thu, Nov 20
SDQ
Santo Domingo
CUZ
Cusco
$821 Roundtrip, found 1 day ago
$821
Roundtrip
found 1 day ago
Select avianca flight, departing Tue, Nov 4 from Santo Domingo to Cusco, returning Thu, Nov 20, priced at $821 found 1 day ago
avianca
Mon, Nov 17 - Wed, Nov 26
SDQ
Santo Domingo
CUZ
Cusco
$855 Roundtrip, found 6 days ago
$855
Roundtrip
found 6 days ago
Select avianca flight, departing Mon, Nov 17 from Santo Domingo to Cusco, returning Wed, Nov 26, priced at $855 found 6 days ago
avianca
Fri, Nov 7 - Mon, Nov 10
SDQ
Santo Domingo
CUZ
Cusco
$869 Roundtrip, found 3 days ago
$869
Roundtrip
found 3 days ago
Select avianca flight, departing Fri, Nov 7 from Santo Domingo to Cusco, returning Mon, Nov 10, priced at $869 found 3 days ago
avianca
Fri, Nov 21 - Wed, Nov 26
SDQ
Santo Domingo
CUZ
Cusco
$873 Roundtrip, found 6 days ago
$873
Roundtrip
found 6 days ago
Select avianca flight, departing Fri, Nov 21 from Santo Domingo to Cusco, returning Wed, Nov 26, priced at $873 found 6 days ago
avianca
Thu, Oct 16 - Thu, Oct 30
SDQ
Santo Domingo
CUZ
Cusco
$901 Roundtrip, found 16 hours ago
$901
Roundtrip
found 16 hours ago
Select avianca flight, departing Thu, Oct 16 from Santo Domingo to Cusco, returning Thu, Oct 30, priced at $901 found 16 hours ago
avianca
Tue, Oct 21 - Mon, Nov 10
SDQ
Santo Domingo
CUZ
Cusco
$902 Roundtrip, found 16 hours ago
$902
Roundtrip
found 16 hours ago
Select avianca flight, departing Tue, Oct 21 from Santo Domingo to Cusco, returning Mon, Nov 10, priced at $902 found 16 hours ago
American Airlines
Mon, Mar 2 - Sat, Mar 14
SDQ
Santo Domingo
CUZ
Cusco
$1,424 Roundtrip, just found
$1,424
Roundtrip
just found
Select American Airlines flight, departing Mon, Mar 2 from Santo Domingo to Cusco, returning Sat, Mar 14, priced at $1,424 just found

Find the cheapest month to fly from Santo Domingo (SDQ) to Cusco (CUZ)

February is typically the cheapest month to fly

From $542 - $1,417 per traveler.

Alternative airports near Cusco

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Alejandro Velasco Astete Intl. CUZ. Cheapest and Closest option available. Average driving time to city center is 4 minutes. Flights from $901
CUZ
Alejandro Velasco Astete Intl.
CheapestClosest
Average driving time to city center4 min
Flights from $901

Frequently asked questions

How much does a flight from Las Americas Intl. Airport (SDQ) to Alejandro Velasco Astete Intl. Airport (CUZ) cost?
Get a cheap one-way flight from $396 or cheap return flight from $783 from Las Americas Intl. Airport (SDQ) to Alejandro Velasco Astete Intl. Airport (CUZ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Las Americas Intl. Airport (SDQ) to Alejandro Velasco Astete Intl. Airport (CUZ)?
October is the cheapest month to fly from SDQ to CUZ. Timing your trip outside of the busy season is often the key to scoring lower fares.
What is the cheapest airline that flies from Las Americas Intl. Airport (SDQ) to Alejandro Velasco Astete Intl. Airport (CUZ)?
To find the cheapest airline flying from SDQ to CUZ, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Las Americas Intl. Airport (SDQ) to Alejandro Velasco Astete Intl. Airport (CUZ)?
You'll have to book a flight with a layover when traveling from Las Americas Intl. Airport (SDQ) to Alejandro Velasco Astete Intl. Airport (CUZ). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to find an option that works for you.
What day of the week has the most flights from SDQ to CUZ?
Usually you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can change based on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Las Americas Intl. Airport (SDQ) to Alejandro Velasco Astete Intl. Airport (CUZ)?
Choose a flight from Las Americas Intl. Airport (SDQ) to Alejandro Velasco Astete Intl. Airport (CUZ) that leaves before 3 PM to reduce the likelihood of delays and cancellations. Departures after this time have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Las Americas Intl. Airport (SDQ) to Alejandro Velasco Astete Intl. Airport (CUZ) last-minute?
Booking your plane ticket from SDQ to CUZ just before your getaway is usually more expensive. However, if you're flexible with your departure dates and times, you could snag a cheap last-minute fare.
Is it cheaper to book a SDQ to CUZ flight and hotel package?
You'll generally save money by securing a SDQ to CUZ flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one convenient place. Once you've selected your ideal accommodations and flights, consider adding extras including car rentals, tours and activities.
Can I cancel or change the date of my flight from Las Americas Intl. Airport (SDQ) to Alejandro Velasco Astete Intl. Airport (CUZ)?
Generally, it's possible to cancel or reschedule your SDQ to CUZ flight. However, if it's been more than 24 hours since booking, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Travel information

Origin airport
Las Americas Intl.
Destination airport
Alejandro Velasco Astete Intl.
Airlines serving
American Airlines, avianca
Roundtrip price
$782
Distance
2214 mi

Book with confidence

Book with confidence

Santo Domingo to Cusco Flights

The cheapest times to fly from Santo Domingo to Cusco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santo Domingo to Cusco are during the month of October. You can find some of the cheapest flights from Santo Domingo to Cusco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santo Domingo to Cusco

Sunday is one of the best days to book for cheap flights from Santo Domingo to Cusco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santo Domingo to Cusco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santo Domingo to Cusco in 2025. You can also book with separate airlines for your outbound and return journeys, from $396 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santo Domingo to Cusco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santo Domingo to Cusco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santo Domingo to Cusco Flights

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