Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search over 321,000 hotels worldwide and 400 airlines worldwide.

Secure incredible value with Expedia's Price Guarantee.

No Expedia cancellation fee to change or cancel almost any hotel reservation.

Cheap SFO to DSM Flights

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Cheap SFO to DSM Flights

Question : How many days should you spend in Des Moines?
Answer : The average time spent in Des Moines by passengers from San Francisco is about one week.

Question : Should you take that vacation to Des Moines in the next 30 days?
Answer : As of Jan 15th, the cheapest day to fly from San Francisco to Des Moines is Jan 16th. Tickets are currently being sold for $228, which is 46% below the average price for this route.

Question : Which airline is offering the cheapest flight from SFO to DSM?
Answer : United Airlines is your best bet for finding that coveted low fare. They're offering fares as low as $228, while prices for other flights are as high as $972.

Question : Would you be willing to change your travel days if it saved you money?
Answer : The lowest-cost day to fly in January is Tuesday. Having flexibility in your travel plans means you can save more, so be sure to plan ahead when possible.

Question : What's the likelihood of you being delayed on this route?
Answer : The best measurement of overall promptness combines both on-time percentage and total delay minutes. SFO to DSM currently has 2 stars out of 5, earning it a far below-average performance compared to the rest of the world.

Question : How often is the San Francisco International Airport (SFO) to Des Moines International Airport (DSM) route delayed?
Answer : The San Francisco to Des Moines route has a 50% on-time rate, ranking in the bottom 50% of the world in getting their passengers to their destinations on schedule. If a flight is delayed, expect an average of less than half an hour added to your flight time.

Question : Do prices fluctuate more for this route than others?
Answer : Ranging from $228 to $972, prices for SFO to DSM do change more than most routes in the United States. However, the sooner you book, the more you'll be able to save.

San Francisco to Des Moines Flights

Sometimes you just need to get out of town or maybe you’re looking for a change of scenery. Regardless of the reason, a flight from San Francisco to Des Moines will do just the trick! Go on, plan to see all the famous landmarks and eat your weight in the local cuisine. Your trip is beckoning, so answer the call by packing your suitcase and filling your travel itinerary with exploring Des Moines.

Whether you’re flying for business or jet-setting on your personal time, you’ve come to the right place. Here at Expedia.com, we’ll pair you up with SFO to DSM flights that won’t make your bank account wince. Ready to temporarily leave behind San Francisco for new horizons? Browse through our cheap airfare, and filter by flight times and dates until you find just what you had in mind. From flights without layovers to ones that arrive early in the morning, you’ll come across plane tickets that suit your travel preferences. You can even bundle your flight to DSM with hotels and car rentals to score even bigger savings.

All set to hit the clouds? Book your travel arrangements with us today and have left-over money to put toward your travel outings and adventures.