$45 Cheap Flights from Tampa (TPA) to St. Louis (STL)

View $45 flight on Sat, Oct 11, 2025Opens in a new window

Popular airlines from Tampa Intl. Airport (TPA) to St. Louis Lambert Intl. Airport (STL)

Cheap Flights from Tampa to St. Louis (TPA-STL)

Prices were available within the past 7 days and start at $45 for one-way flights and $90 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Sat, Oct 18 - Sat, Oct 25
TPA
Tampa
STL
St. Louis
$90 Roundtrip, found 4 hours ago
$90
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Sat, Oct 18 from Tampa to St. Louis, returning Sat, Oct 25, priced at $90 found 4 hours ago
Southwest Airlines
Wed, Oct 15 - Sat, Oct 18
TPA
Tampa
STL
St. Louis
$114 Roundtrip, found 6 hours ago
$114
Roundtrip
found 6 hours ago
Select Southwest Airlines flight, departing Wed, Oct 15 from Tampa to St. Louis, returning Sat, Oct 18, priced at $114 found 6 hours ago
Southwest Airlines
Wed, Nov 12 - Sat, Nov 15
TPA
Tampa
STL
St. Louis
$120 Roundtrip, found 5 days ago
$120
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Wed, Nov 12 from Tampa to St. Louis, returning Sat, Nov 15, priced at $120 found 5 days ago
Southwest Airlines
Wed, Oct 15 - Sat, Oct 18
TPA
Tampa
STL
St. Louis
$124 Roundtrip, found 6 hours ago
$124
Roundtrip
found 6 hours ago
Select Southwest Airlines flight, departing Wed, Oct 15 from Tampa to St. Louis, returning Sat, Oct 18, priced at $124 found 6 hours ago
Southwest Airlines
Mon, Oct 20 - Sat, Oct 25
TPA
Tampa
STL
St. Louis
$130 Roundtrip, found 4 days ago
$130
Roundtrip
found 4 days ago
Select Southwest Airlines flight, departing Mon, Oct 20 from Tampa to St. Louis, returning Sat, Oct 25, priced at $130 found 4 days ago
Southwest Airlines
Fri, Sep 19 - Mon, Sep 22
TPA
Tampa
STL
St. Louis
$137 Roundtrip, found 1 hour ago
$137
Roundtrip
found 1 hour ago
Select Southwest Airlines flight, departing Fri, Sep 19 from Tampa to St. Louis, returning Mon, Sep 22, priced at $137 found 1 hour ago
Frontier Airlines
Sat, Oct 18 - Sat, Oct 25
TPA
Tampa
STL
St. Louis
$138 Roundtrip, found 4 hours ago
$138
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Sat, Oct 18 from Tampa to St. Louis, returning Sat, Oct 25, priced at $138 found 4 hours ago
Delta
Wed, Oct 15 - Sat, Oct 18
TPA
Tampa
STL
St. Louis
$144 Roundtrip, found 6 hours ago
$144
Roundtrip
found 6 hours ago
Select Delta flight, departing Wed, Oct 15 from Tampa to St. Louis, returning Sat, Oct 18, priced at $144 found 6 hours ago
American Airlines
Wed, Nov 12 - Sat, Nov 15
TPA
Tampa
STL
St. Louis
$145 Roundtrip, found 5 days ago
$145
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Nov 12 from Tampa to St. Louis, returning Sat, Nov 15, priced at $145 found 5 days ago
United
Wed, Oct 15 - Sat, Oct 18
TPA
Tampa
STL
St. Louis
$154 Roundtrip, found 6 hours ago
$154
Roundtrip
found 6 hours ago
Select United flight, departing Wed, Oct 15 from Tampa to St. Louis, returning Sat, Oct 18, priced at $154 found 6 hours ago

Find the cheapest month to fly from Tampa (TPA) to St. Louis (STL)

October is typically the cheapest month to fly

From $126 - $337 per traveler.

Graph displaying average flight prices per month

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $360
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $360
Flights from Tampa (TPA) to St. Louis (STL)
Origin airport
Tampa Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, Spirit Airlines, United
Roundtrip price
$90
Distance
869 mi
Average flight time
1 hour 58 mins

Tampa to St. Louis Flights

The cheapest times to fly from Tampa to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Tampa to St. Louis are during the month of October. You can find some of the cheapest flights from Tampa to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Tampa to St. Louis

Sunday is one of the best days to book for cheap flights from Tampa to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Tampa to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Tampa to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $45 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Tampa to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Tampa to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Tampa Intl. Airport (TPA) to Lambert-St. Louis Intl. Airport (STL) cost?
Snag a cheap one-way flight from $45 or cheap return flight from $90 from Tampa Intl. Airport (TPA) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Tampa Intl. Airport (TPA) to Lambert-St. Louis Intl. Airport (STL)?
The cheapest month to fly from TPA to STL is October, when demand is low. Off-peak months are usually when better flight deals are available between these airports.
Which airlines fly direct from Tampa Intl. Airport (TPA) to Lambert-St. Louis Intl. Airport (STL)?
When jetting out of Tampa Intl. Airport (TPA), you can jump on a direct flight to Lambert-St. Louis Intl. Airport (STL) with Southwest Airlines.
What is the cheapest airline that flies from Tampa Intl. Airport (TPA) to Lambert-St. Louis Intl. Airport (STL)?
To find the cheapest airline flying from TPA to STL, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Tampa Intl. Airport (TPA) to Lambert-St. Louis Intl. Airport (STL)?
Each day, an average of 3 nonstop flights take off from Tampa Intl. Airport (TPA) to Lambert-St. Louis Intl. Airport (STL). Select the departure date that best fits your schedule.
What are the most popular departure times for flights from Tampa Intl. Airport (TPA) to Lambert-St. Louis Intl. Airport (STL)?
More people fly between TPA and STL at 8 AM than at any other time. Looking for a quieter experience? Travel outside of rush hours and you could save on your fare as well.
What day of the week has the most flights from TPA to STL?
Depart on a Friday if you're looking for the largest selection of flights from Tampa Intl. Airport (TPA) to Lambert-St. Louis Intl. Airport (STL).
What is the earliest flight from Tampa Intl. Airport (TPA) to Lambert-St. Louis Intl. Airport (STL)?
Tampa Intl. Airport (TPA)'s earliest flight to Lambert-St. Louis Intl. Airport (STL) leaves at approximately 6:55AM UTC-5. With a travel duration of 2h 35m, you'll arrive at around 8:30AM UTC-6.
How long does it take to fly from Tampa Intl. Airport (TPA) to Lambert-St. Louis Intl. Airport (STL)?
Flights from TPA to STL have an average travel time of 2 hours and 33 minutes. The distance between the two is 870 mi.
What is the best time to fly from Tampa Intl. Airport (TPA) to Lambert-St. Louis Intl. Airport (STL)?
To arrive at Lambert-St. Louis Intl. Airport (STL) without delays, select a flight that leaves Tampa Intl. Airport (TPA) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for St. Louis from Tampa Intl. Airport (TPA)?
Lambert-St. Louis Intl. Airport (STL) is the only airport in St. Louis with direct flights from Tampa Intl. Airport (TPA). Consider the available options and find affordable fares on Expedia.
Is it cheaper to buy a plane ticket from Tampa Intl. Airport (TPA) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Booking your plane ticket from TPA to STL right before your trip is generally more expensive. However, if you're flexible with your travel times and dates, you could grab a cheap last-minute fare.
Is it cheaper to book a TPA to STL flight and hotel package?
Opting for a TPA to STL flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Pick from our impressive range of stays and then add activities, flights and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Tampa Intl. Airport (TPA) to Lambert-St. Louis Intl. Airport (STL)?
Typically, you can cancel or reschedule your TPA to STL flight. However, additional charges may apply, especially if you booked more than 24 hours ago. Check your itinerary for the airline's policies and fees on flight changes, or if you want further information, go to our Customer Service portal.

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*Available to One Key members.