Mesopotamia Romantic Vacations 2026

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Top Romantic vacation packages in Mesopotamia

Price found within the past 48 hours. Click for updated prices.

Falls Iguazú Hotel & Spa

Save 100% on your flight

$480

per person

Oct 5 - Oct 8

found 1 day ago

Roundtrip flight included

Buenos Aires (BUE) to Iguazu (IGR)

9.2/10 Wonderful! (487 reviews)

The hotel is a standard type with beautiful grounds and pool. The rooms are clean and roomy with all the traditional comforts of contemporary hotel. The stay includes breakfast and dinner but the dinner service is basic. The staff is very professional and helpful- they assisted us with our last minute requests.

Reviewed on Jul 18, 2026

Gran Melia Iguazú

$1,111

per person

Nov 13 - Nov 16

found 1 day ago

Roundtrip flight included

São Paulo (GRU) to Iguazu (IGR)

9.4/10 Exceptional! (1,005 reviews)

Iguazu Grand Resort Spa & Casino

Save 100% on your flight

$688

per person

Nov 13 - Nov 16

found 1 day ago

Roundtrip flight included

São Paulo (GRU) to Iguazu (IGR)

9.2/10 Wonderful! (678 reviews)

Excellent location, lovely friendly staff, beautiful property full of amenities Very spacious room. Great value for money. Would highly recommend it.

Reviewed on Aug 31, 2026

Loi Suites Iguazú Hotel

$745

per person

Nov 13 - Nov 16

found 1 day ago

Roundtrip flight included

São Paulo (GRU) to Iguazu (IGR)

9.2/10 Wonderful! (1,004 reviews)

Hotel Saint George

Comandante Andresito

$523

per person

Nov 13 - Nov 16

found 1 day ago

Roundtrip flight included

São Paulo (GRU) to Iguazu (IGR)

9/10 Wonderful! (1,011 reviews)

Don't see what you're looking for?

See all available trips from Columbus to Mesopotamia

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5* Romantic vacations in Mesopotamia

Price found within the past 48 hours. Click for updated prices.

Iguazu Grand Resort Spa & Casino

Save 100% on your flight

$688

per person

Nov 13 - Nov 16

found 1 day ago

Roundtrip flight included

São Paulo (GRU) to Iguazu (IGR)

9.2/10 Wonderful! (678 reviews)

Excellent location, lovely friendly staff, beautiful property full of amenities Very spacious room. Great value for money. Would highly recommend it.

Reviewed on Aug 31, 2026

Gran Melia Iguazú

$1,111

per person

Nov 13 - Nov 16

found 1 day ago

Roundtrip flight included

São Paulo (GRU) to Iguazu (IGR)

9.4/10 Exceptional! (1,005 reviews)

Loi Suites Iguazú Hotel

$745

per person

Nov 13 - Nov 16

found 1 day ago

Roundtrip flight included

São Paulo (GRU) to Iguazu (IGR)

9.2/10 Wonderful! (1,004 reviews)

Don't see what you're looking for?

See all available trips from Columbus to Mesopotamia

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3 Night Romantic vacations in Mesopotamia

Price found within the past 48 hours. Click for updated prices.

Iguazu Grand Resort Spa & Casino

Save 100% on your flight

$688

per person

Nov 13 - Nov 16

found 1 day ago

Roundtrip flight included

São Paulo (GRU) to Iguazu (IGR)

9.2/10 Wonderful! (678 reviews)

Excellent location, lovely friendly staff, beautiful property full of amenities Very spacious room. Great value for money. Would highly recommend it.

Reviewed on Aug 31, 2026

Gran Melia Iguazú

$1,111

per person

Nov 13 - Nov 16

found 1 day ago

Roundtrip flight included

São Paulo (GRU) to Iguazu (IGR)

9.4/10 Exceptional! (1,005 reviews)

Loi Suites Iguazú Hotel

$745

per person

Nov 13 - Nov 16

found 1 day ago

Roundtrip flight included

São Paulo (GRU) to Iguazu (IGR)

9.2/10 Wonderful! (1,004 reviews)

Don't see what you're looking for?

See all available trips from Columbus to Mesopotamia

View all trips

4 Night Romantic vacations in Mesopotamia

Price found within the past 48 hours. Click for updated prices.

IGUAZU JUNGLE HOTEL

Villa Catorce

$2,005

per person

Nov 18 - Nov 20

found 1 day ago

Roundtrip flight included

Los Angeles (QLA) to Iguazu (IGR)

9.4/10 Exceptional! (887 reviews)

Gran Melia Iguazú

$2,357

per person

Nov 18 - Nov 20

found 1 day ago

Roundtrip flight included

Los Angeles (QLA) to Iguazu (IGR)

9.4/10 Exceptional! (1,005 reviews)

Loi Suites Iguazú Hotel

$2,120

per person

Nov 18 - Nov 20

found 1 day ago

Roundtrip flight included

Los Angeles (QLA) to Iguazu (IGR)

9.2/10 Wonderful! (1,004 reviews)

Don't see what you're looking for?

See all available trips from Columbus to Mesopotamia

View all trips

How can I find the best Mesopotamia vacation packages for couples?

To win over the love of your life, first choose where and when you want to bring the romance. Now flirt with the filters to add ocean views, spa, pools, and anything else that gets your heart racing.

How can I find cheap Mesopotamia romantic packages for two?

For dollar-friendly delights, sort your search results by price or deals. You can also filter by budget to find romantic retreats at prices you’ll love. For an affordable and alluring adventure, try self-catering.

How can I plan a great romantic trip to Mesopotamia?

Find what fills you with joy and dive right in, whether you thrill in a little adventure or lust for long lazy days by the pool, handcrafted cocktails in hand. Fire cupid’s arrow at our filters and build your dream trip for two.

How much is a trip for two to Mesopotamia?

Put a price on love with stunning deals for duos starting at just $480. Prices and availability are subject to change. Additional terms may apply.

Can I book Mesopotamia spa packages for couples?

Check the filter box for a seductive stay at a spa. Sort your results by price, deals, rating, and more to guarantee the perfect match.

How can I book romantic weekend getaway packages in Mesopotamia?

To book a loved-up break in Mesopotamia, enter your travel dates and sort by price, deals, rating—whatever matters most to you and your partner. Now, you can add some adult-only amenities, like a hot tub or full-service spa for total R, R, & R (that’s romance, rest, and recuperation).

Can I book a romantic trip to Mesopotamia with free cancellation and/or flexible dates?

The course of true love should always run smooth, but we get that there are hiccups. So, filter by payment option to search for romantic stays with free cancellation and buy now, pay later options.

Why should I book my Mesopotamia romantic holiday with Expedia?

If you’ve only got eyes for excellent escapes, book your loved-up break with Expedia. Fling the filters to find accommodation you’ll adore. And what’s more attractive than ATOL protection?

Top Romantic Mesopotamia Hotels

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

Rodovia Br 469 Km 32 Foz do Iguaçu PR

17 hours drive from Termas de Federacion

Fall in love again at this boutique hotel. You and your special someone are sure to love the spa, garden, and 2 restaurants. You'll also appreciate the lobby ...

10/10 Exceptional! (1,005 reviews)

Couples like: full-service spa, couples spa treatments, bar

Travelers say...

"Amazing stay"

Reviewed on Sep 3, 2026

La Aldea de la Selva Lodge

Selva Iriapú S / N Puerto Iguazú Misiones

17 hours drive from Termas de Federacion

For a romantic stay, consider this Art Deco lodge, featuring in-room massages, a garden, and jetted tubs. Couples will appreciate the hot tub and luxury ...

8.8/10 Excellent! (587 reviews)

Couples like: bar, spa tub

Travelers say...

"Really pretty property. Room was nice and clean. Breakfast was good. Staff was very helpful. We had a great stay."

Reviewed on Aug 19, 2026

IGUAZU JUNGLE HOTEL

Avenida Hipolito Irigoyen s/n Puerto Iguazú Misiones

17 hours drive from Termas de Federacion

In-room massages, a garden, and onsite dining await couples visiting this romantic hotel. The property also offers a terrace, an outdoor pool, and a waterfront ...

See all 527 properties in Mesopotamia

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.