Name: O2 Hotel Gualeguaychú
Price range: $42 total

Your Mesopotamia Vacation

When you long for adventure, book a Mesopotamia vacation package. Get set to enjoy culture, nature, festivals, and much more in this vibrant destination. A trip to Mesopotamia wouldn't be complete without getting to some of its leading cities, starting with Corrientes. Two of the top attractions here include Museo de Artesanías Tradicionales Folclóricas and Casinos del Litoral. Concordia is another favorite with Mesopotamia travelers. Visitors to this exciting city love Termas Del Ayui and Concordia Speedway. Whether you're traveling on a shoestring or want to splurge, Expedia are here to help you customize your next Mesopotamia vacation.

The Latest Mesopotamia vacation packages

Price found within the past 48 hours. Click for updated prices.

Regente Palace Hotel

El Centro

$908

per person

Nov 27 - Dec 4

found 1 day ago

Roundtrip non-stop flight included

Miami (MIA) to Buenos Aires (EZE)

7.6/10 Good! (425 reviews)

La ubicación del hotel es de lo mejor, cerca de los lugares que todo turista debe conocer. Restaurantes cercanos de buena calidad. Faltan algunos detalles en mantenimiento pero es comprensible de una edificación con muchos años de construcción. Desayuno excelente.

Reviewed on Jul 28, 2026

Regal Pacific Buenos Aires

El Centro

$1,108

per person

Nov 27 - Dec 4

found 1 day ago

Roundtrip non-stop flight included

Miami (MIA) to Buenos Aires (EZE)

8.8/10 Excellent! (1,000 reviews)

Melia Recoleta Plaza

Recoleta

$1,730

per person

Nov 27 - Dec 4

found 7 hours ago

Roundtrip flight included

Miami (MIA) to Buenos Aires (EZE)

9/10 Wonderful! (897 reviews)

The entire staff was excellent. Tobias and Andres went out of their way to be helpful. It's a great boutique hotel within walking distance to restaurants, shopping and enjoying the beauty and charm of Recoleta. The gym is tiny but there are plenty of gyms near-by. The restaurant was very good and provided a nice breakfast.

Reviewed on Oct 21, 2026

Alvear Palace Hotel

Recoleta

Save 100% on your flight

$2,668

per person

Nov 27 - Dec 4

found 1 day ago

Roundtrip non-stop flight included

Miami (MIA) to Buenos Aires (EZE)

9.6/10 Exceptional! (1,001 reviews)

Live Devoto Boutique Apartments

Villa Devoto

$1,361

per person

Nov 27 - Dec 4

found 1 day ago

Roundtrip flight included

Miami (MIA) to Buenos Aires (EZE)

10/10 Exceptional! (2 reviews)

The apartment was more than I was expecting. They have a roof that is a plus. Modern, clean and super confortable place.

Reviewed on Jun 8, 2026

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See all available trips from Columbus to Mesopotamia

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Stay near popular Mesopotamia attractions

A dirt path through a dense palm tree forest.

El Palmar National Park

8.0/10 (2 reviews)

Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay.

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Mesopotamia Hotel Deals

Marriott Corrientes Hotel

Av Costanera Juan Pablo II y Lavalle Corrientes

Fully refundableReserve now, pay when you stay

$161 nightly

$161 total

Nov 4 - Nov 5

Costarenas Hotel & Spa

12 de Abril y Quiros Colon Entre Rios

$122 nightly

$122 total

Oct 29 - Oct 30

8.8/10 Excellent! (65 reviews)

"Estaba todo muy lindo"

Reviewed on Jun 8, 2026

O2 Hotel Gualeguaychú

115 3 de Febrero Gualeguaychú Entre Ríos

Fully refundableReserve now, pay when you stay

$42 nightly

$42 total

Oct 29 - Oct 30

See all 531 properties in Mesopotamia

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.