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Featured Panama 4 Star Hotels

See all 500 Hotels in Panama
Crowne Plaza Panama Airport

Crowne Plaza Panama Airport

Ave. Domingo Diaz, Tocumen
4.0 out of 5.0
4.3 out of 5 (490 reviews)
Location & staffLocation is ideal !! Staff is fantastic, they even fix disasters created by Expedia !!!
  Nov 20, 2017

$101

$101
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Vía Tocumen, Tocumen
4.0 out of 5.0
4.0 out of 5 (1,810 reviews)
Close to the airport Location close to the airport is great. The down was that it diesnt have elevator, so rooms on second floor when you have heavy luggage are not convenient.
  Nov 20, 2017

$86

$86
Novotel Panama City

Novotel Panama City

Calle Jose I. Fabrega y Thais de Pons, Panama City
4.0 out of 5.0
4.3 out of 5 (696 reviews)
Nice hotel near to everything Nice Hotel with very nice staff , Almost close to everything.Fair price through Expedia ,would love to stay every time !
  Nov 22, 2017

$60

$60
Hard Rock Hotel Panama Megapolis

Hard Rock Hotel Panama Megapolis

Ave. Balboa al lado de Multicentro, Panama City
4.5 out of 5.0
4.3 out of 5 (2,188 reviews)
GREAT VIEW AND POOLI am a Pool Jogger. It is my favorite workout since I had a hip replacement. What a rooftop pool. It overlooked the city and the ambiance at the site was so cool. My martini cost me $16 however. I ended up getting my drinks across the street at the Red Rooster (nice sports bar) My room on the 38th ...
  Nov 20, 2017

$89

$89
RIU Plaza Panama

RIU Plaza Panama

Calle 50, Urb. Marbella, Panama City
4.0 out of 5.0
4.4 out of 5 (1,486 reviews)
Nice hotel, luxuriousThe staff is very kind since you enter the hotel, very big and comfortable. We have an upgrade room thanks to Expedia VIP , then we have a problem with a water filtration and the hotel with no hesitation change us to a suite very very nice, we really appreciate nothing less to expect with so go hotel ...
  Nov 19, 2017

$85

$85
DoubleTree by Hilton Hotel Panama City

DoubleTree by Hilton Hotel Panama City

Via Espana, Federico Boyd & Bella Vista, Panama City
4.0 out of 5.0
4.1 out of 5 (1,500 reviews)
Bad restaurant staffBad Service in restaurant staff. few people attending.
  Nov 20, 2017

$60

$60
Courtyard Panama at Multiplaza Mall

Courtyard Panama at Multiplaza Mall

Via Israel Multiplaza Pacific Mall, Panama City
4.0 out of 5.0
4.2 out of 5 (462 reviews)
Convenient locationA very good hotel right at the entrance of Multiplaza Pacific. Nice mall to visit and eat! The hotel is very clean. Beds are good. Pillows awful. The place is quiet. We enjoyed the stay. Guys at the reception during nights are not polite. However day shift works perfectly well.
  Nov 23, 2017

$84

$84
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

Av. Balboa con Calle 53, Panama City
4.0 out of 5.0
4.4 out of 5 (102 reviews)
Nice rooms with city view and great food at the restaurant!
  Nov 21, 2017

$97

$97
Occidental Panamá City

Occidental Panamá City

Avenida 2da Sur, Obarrio, Bella Vista, Panama City
4.0 out of 5.0
4.1 out of 5 (678 reviews)
Everything fine. I only stayed 1 night. Personel where very friendly
  Nov 21, 2017

$54

$54
Radisson Decapolis Panama City

Radisson Decapolis Panama City

Avenida Balboa Con Multicentro, Panama City
4.0 out of 5.0
4.4 out of 5 (585 reviews)
Great overnight stayStaff is really helpful and provided excellent service. Great breakfast with lots of choices included with the room. The room was nice but the beds were hard and not very comfortable. The hotel restaurant is very nice and had a great dinner. The hotel has a walkway to a 4 story mall if you want to ...
  Nov 16, 2017

$98

$98
Map

The preparation of any much-needed holiday starts with picking a location. Panama has become a popular option with tourists because it offers so much to do. But, "location, location, location" applies to more than just your destination. When you want a trip that is great from beginning to end, you need the ideal hotel.

Accommodations as Scenic as Panama

Panama saw its fair share of visitors in the last year. Expedia's review section boast tips and tricks which may help you decide which lodge is optimal for your vacation. When you book a 4-star suite you can breathe easy knowing that these properties are designed to meet your needs. These hotels aim to make the facilities and grounds welcoming during your vacation. You won't have to search for to keep up with your exercise routine, an invigorating dip, or nice meal. Panama has dozens of fantastic lodgings that provide the perfect escape.

Rooms have been furnished to keep you as cozy as possible, with amenities like ultra-comfortable bedding, specially designed bathroom products, and in-room coffee or tea. So, sit back and relax. Moreover, if you find yourself in need of anything else, you can trust the staff will work their hardest to ensure you stay pleased during your stay. These accommodations are so nice that you'll regret the day you have to check-out.

Book a 4-Star Hotel in Panama Today!

A getaway to Panama should be one where you don't have to be concerned about the little things. With Expedia, you will get great deals on the best accommodations to take your getaway to greater heights.

Recently booked 4 Star Hotels in Panama

Ramada Plaza Panama Punta Pacifica
4.0 out of 5.0
Last booking: 33 minutes ago
Crowne Plaza Panama Airport
4.0 out of 5.0
Last booking: 5 hours ago
RIU Plaza Panama
4.0 out of 5.0
Last booking: 6 hours ago
Wyndham Panama Albrook Mall
4.0 out of 5.0
Last booking: 6 hours ago
DoubleTree by Hilton Hotel Panama City
4.0 out of 5.0
Last booking: 6 hours ago